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C3 polymorphism and the antibody titres in pregnancy: use of a non-barbital buffer for C3 typing.
The C3 phenotypes were examined in 391 pregnant women classified according to the level of 'immune', 'natural' and 'irregular' antibody titres. No significant association between the C3 types and antibody levels was found. The sera were also typed for C3 with a non-barbital buffer
Diabetic pregnancy: evidence of selection on the Rh blood group system.
The blood glucose levels of pregnant women with insulin-dependent diabetes mellitus and the blood glucose levels of newborns during the first few hours of life show an association with maternal Rh genotype. Distortions of joint maternal-fetal Rh phenotype distribution have also been observed. Because a cluster of genes involved in glycide metabolism is located on the short arm of chromosome 1, the present observations may reflect the action of these genes
Relationship between human serum placental alkaline phosphatase and the ABo and Rh compatibility status in pregnancy.
Immunologic follow-up of infants treated with granulocyte transfusion for neonatal sepsis.
The immunologic status and the occurrence of alloimmunization against granulocytes, platelets, lymphocytes, and red cells was evaluated in 33 babies who received granulocyte transfusion because of neonatal sepsis. Nine age-matched babies were examined as control. A first group of 19 infants was examined only once between 6 and 23 months of age. Alloantibodies were searched by the following serologic methods: standard techniques for red cell antibodies; lymphocytotoxicity test; agglutination and immunofluorescence tests on granulocytes and platelets. No antibodies were demonstrated. The immunologic profile was investigated by determining the Ig levels, the percentage of E rosette-forming cells, and the lymphocyte blastic response to phytohemagglutinin and concanavalin A. Granulocyte function was studied by phagocytosis and killing of Candida. No significant differences were observed between treated and control babies. In a second group of 14 infants the occurrence of early immunization within 3 to 9 weeks after the last transfusion was investigated. No evidence of early immunization was found. The present data suggest that following neonatal granulocyte transfusion the risk of adverse immune reactions should be low
Genetic polymorphisms of the A and B subunits of human coagulation factor XIII in mainland Italy and Sardinia: Description of a new FXIIIA variant allele
[No abstract available
Distribution of ORM1, C6, C7 and APO C-II allele frequencies in populations from mainland Italy and Sardinia.
Is there a role of erythrocyte acid phosphatase polymorphism in intrauterine development?
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