1,721,028 research outputs found

    From congenital to idiopathic adult hydrocephalus: A historical research

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    Reports of idiopathic adult hydrocephalus prior to the 1965 description of idiopathic normal pressure hydrocephalus by Salomón Hakim and Raymond Adams are lacking in the literature. Congenital paediatric and congenital adult hydrocephalus were considered to trace the early descriptions of idiopathic adult hydrocephalus. Through traditional or digital libraries and internet search engines, the historical sources dealing with idiopathic adult hydrocephalus were explored. The research shows that many distinguished physicians through the centuries have contributed to the discovery of idiopathic adult hydrocephalus. Early descriptions of the disorder were related to autopsy studies in the 18th and 19th centuries. From the second half of the 1800s, idiopathic adult hydrocephalus appeared to have been forgotten in the medical literature. © The Author (2010)

    Disturbi del circolo liquorale

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    Il liquido cerebrospinale o “ liquor” permea tutto lo spazio subaracnoideo, colmando il vuoto esistente tra il nevrasse e le meningi. La funzione principale del liquor è quella di dissipare energia e fornire protezione alle strutture intracraniche in occasione di brusche accelerazioni, come ad esempio nei traumi cranici. Oltre a funzioni meccaniche, il liquor svolge funzioni trofiche e immunologiche (vedi anche capitolo sulla Diagnostica liquorale). Il liquor è prodotto incessantemente (tra 400 e 500 ml ogni 24 ore) dai plessi corioidei contenuti all’interno dei ventricoli. Considerando che il contenuto totale di liquor è, tra spazio intracranico e spazio spinale, di circa 140 ml, appare evidente che questo volume può essere mantenuto solo grazie a un processo di continuo riassorbimento liquorale. Quest’ultimo si realizza a livello della convessità cranica, in corrispondenza di alcune strutture specializzate incluse nello spessore della dura madre e note come granulazioni o villi aracnoidali. Attraverso un processo di filtrazione complesso e non ancora del tutto chiaro, i villi aracnoidali convogliano il liquor assorbito nelle vene proprie della dura madre e, in ultima analisi, nel seno longitudinale superiore. Esiste, pertanto, una correlazione tra pressione venosa centrale, volume liquorale e pressione intracranica. Il “circolo liquorale” è il percorso che il liquor compie dalla sede di produzione a quella di riassorbimento. Schematizzando, il liquor prodotto a livello di un ventricolo laterale raggiunge il 3° ventricolo attraversando il rispettivo forame di Monro, quindi il 4° ventricolo attraverso l’acquedotto di Silvio, gli spazi subaracnoidei basali attraversando i forami di Luschka e Magendie; percorre diffusamente gli spazi subaracnoidei della convessità e raggiunge le granulazioni aracnoidali. Parte del liquor è dislocato nel canale spinale a livello perimidollare; il travaso di liquor dal compartimento intracranico a quello spinale è uno dei primi e più efficaci sistemi messi in atto dall’organismo per contenere aumenti della pressione intracranica

    Intraspinous postlaminectomy pseudomeningocele

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    Pseudomeningoceles are uncommon complications of lumbar surgery. They are encapsulated cerebrospinal fluid collections developing extradurally as a consequence of incidental dural tears. They are typically located in the paraspinal compartment and occasionally reach the subcutaneous space. We describe the case of a patient in whom a postlaminectomy pseudomeningocele developed over a 10-year period within the L5 spinous process and remained completely encircled within its bony boundaries. The surgical implications of this finding are discussed

    Resection of a left insular cavernoma aided by a simple navigational tool. Technical note

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    Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is viewed by many as the ultimate therapy targeting severe advanced stages of Parkinson's disease (PD). A fundamental constituent of the mechanisms underlying the therapeutic effects of DBS is clearly the functional organization of the STN; however, there is limited understanding of the organization of this structure in humans. Data from primates suggest that different domains can be identified in the STN, including a sensorimotor area with a segregated body map, as well as nonmotor areas. Recent clinical studies have used microelectrode recording to investigate the presence of a body map in the sensorimotor STN of PD patients. This paper will review and compare experimental and clinical data regarding the functional organization of the STN and discuss the clinical implications for PD patients undergoing STN DBS

    Combined intra-extracanal approach to lumbosacral disc herniations with bi-radicular involvement. Technical considerations from a surgical series of 15 cases.

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    Large lumbosacral disc herniations effacing both the paramedian and the foraminal area often cause double radicular compression. Surgical management of these lesions may be difficult. A traditional interlaminar approach usually brings into view only the paramedian portion of the intervertebral disc, unless the lateral bone removal is considerably increased. Conversely, the numerous far-lateral approaches proposed for removing foraminal or extraforaminal disc herniations would decompress the exiting nerve root only. Overall, these approaches share the drawback of controlling the neuroforamen on one side alone. A combined intra-extraforaminal exposure is a useful yet rarely reported approach. Over a 3-year period, 15 patients with bi-radicular symptoms due to large disc herniations of the lumbar spine underwent surgery through a combined intra-extracanal approach. A standard medial exposure with an almost complete hemilaminectomy of the upper vertebra was combined with an extraforaminal exposure, achieved by minimal drilling of the inferior facet joint, the lateral border of the pars interarticularis and the inferior margin of the superior transverse process. The herniated discs were removed using key maneuvers made feasible by working simultaneously on both operative windows. In all cases the disc herniation could be completely removed, thus decompressing both nerve roots. Radicular pain was fully relieved without procedure-related morbidity. The intra-extraforaminal exposure was particularly useful in identifying the extraforaminal nerve root early. Early identification was especially advantageous when periradicular scar tissue hid the nerve root from view, as it did in patients who had undergone previous surgery at the same site or had long-standing radicular symptoms. Controlling the foramen on both sides also reduced the risk of leaving residual disc fragments. A curved probe was used to push the disc material outside the foramen. In conclusion, specific surgical maneuvers made feasible by a simultaneous extraspinal and intraspinal exposure allow quick, safe and complete removal of lumbosacral disc herniations with paramedian and foraminal extension

    Intraparenchymal haemorrhage after a cerebrospinal fluid tap-test for secondary normal pressure hydrocephalus

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    The lumbar tap test as a diagnostic and therapeutic procedure in idiopathic normal pressure hydrocephalus is used widely. Complications from lumbar punctures are rare. We report a man who underwent a tap-test for secondary normal pressure hydrocephalus, and after clinical improvement, suffered a fatal intraparenchymal brain haemorrhage three days later. © 2012 Elsevier Ltd. All rights reserved
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