1,355,133 research outputs found

    Josie Montoya Montano with Palladini kids in front of beauty shop sign

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    Josie Montoya Montano and Palladini children in front of Palladini house with beauty shop sign, plus a snow ma

    Adelaida Palladini Perea

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    Adelaida Palladini Perea standing by a plant; wife of Abenecio Perea, great aunt of Pietro Palladin

    Lexicon for an Affective Archive

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    To study an archive or archival materials is to encounter an affective and critical practice involved in the construction of memory. Lexicon for an Affective Archive, edited by Giulia Palladini and Marco Pustianaz, is an international collection of these encounters, offering glimpses into the intimate relations inherent in finding, remembering (or imagining), and creating an archive. Bringing together voices from a variety of fields across the humanities, performance studies, and contemporary art, and engaging in a multidisciplinary analysis, this beautifully designed and fully illustrated volume advances the idea of an “affective archive” as a useful conceptual tool—a tool which contributes to an understanding of an expanded notion of an archive and its central role in contemporary visual and performing arts

    Detection of a virus related to betacoronaviruses in Italian greater horseshoe bats

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    The association between coronaviruses and bats is a worldwide phenomenon and bats belonging to genus Rhinolophus are the reservoir host for several coronaviruses, including a large number of viruses closely related genetically to severe acute respiratory syndrome-coronavirus (SARS-CoV). We carried out a survey in colonies of Italian bats (Rhinolophus ferrumequinum) for the presence of coronaviruses. Two of 52 R. ferrumequinum captured from different Italian areas tested positive by reverse transcription-PCR for a fragment of RNA-dependent RNA polymerase (RdRp) gene of viruses related to Coronavirus. Phylogenetic analysis revealed close correlations between one of the positive samples and SARS-related CoV belonging to the genus Betacoronavirus

    Monoclonal Antibody Therapies in Systemic Light-Chain Amyloidosis

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    In systemic light-chain amyloidosis, monoclonal antibodies target antigens that are either membrane-bound or circulating or deposited in the organs. CD38 holds high promise as a target against clonal plasma cells. Multiple anti-CD38 antibodies are either approved for use or being investigated in clinical trials. Daratumumab has been investigated and has clinical efficacy in upfront or refractory settings. High rates of hematologic response are seen with daratumumab, which translates to high organ response rates. Rituximab is usually integrated into the treatment regimen for IgM amyloidosis. Anti-amyloid therapies have shown preclinical proof of principle, but lack confirmation of improvement
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