1,721,124 research outputs found
Roflumilast is safe and effective in improving symptoms and lung function in severe COPD
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Pulmonary gas exchange and ventilatory efficiency during exercise in health and diseases.
No full textCardiopulmonary exercise testing (CPET) is nowadays used to study the exercise response in healthy subjects and in disease. Ventilatory efficiency is one of the main determinants in exercise tolerance, and its main variables are a useful tool to guide pathophysiologists toward specific diagnostic pathways, providing prognostic information and improving disease management, treatment, and outcome
Standardized PaO2/FiO2 ratio in COVID-19: Added value or risky assumption. Author's reply
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Supplemental oxygen and heliox: 'new' tools for exercise training in chronic obstructive pulmonary disease.
No full textExercise and airway physiology: interactions with immune and allergic responses
No full textIn this chapter, the relationships between exercise and lung function are analysed. The
presence of airflow obstruction may impede an efficient ventilatory response to
exercise because of the occurrence of dynamic hyperinflation. In normal subjects,
bronchodilation may occur during exercise and this may also be true in asthmatics that
are bronchoconstricted at rest. However, in a number of asthmatics with normal lung
function at rest, bronchoconstriction may occur after a short submaximal exercise or
even during it if the bout is prolonged. The mechanisms by which exercise-induced
bronchoconstriction develop are triggered by thermodynamic events and involve
inflammatory cells present in the airways at the time of exercise. Furthermore, recent
data suggest that exercise may prime airway inflammation, thus leading to airway
hyperresponsiveness in elite athletes
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