150,368 research outputs found
sj-docx-2-pal-10.1177_08258597221086767 - Supplemental material for Virtual Reality Exposure Therapy in Palliative Care: A Case Series
No full textSupplemental material, sj-docx-2-pal-10.1177_08258597221086767 for Virtual Reality Exposure Therapy in Palliative Care: A Case Series by A. Seiler, M. Schettle, M. Amann, Sophie Gaertner, Stefan Wicki, S.M. Christ, G. Theile, M. Feuz, C. Hertler, and D. Blum in Journal of Palliative Care</p
PAL-CRID3 binding requires an intact (d)ATP-binding pocket and fails to bind CAPS-associated NLRP3 mutants.
No full text(A) Schematic diagram of NLRP3 depicting the different domains used in this study. (B) HEK293T cells transfected with the indicated plasmids were incubated with PAL-CRID3 in the absence or presence of free MCC950/CRID3 and subsequently irradiated. After cells are lysed, click chemistry is performed, and lysates are assayed by TAMRA imaging and by immunoblot analysis with the indicated antibodies. (C–F) HEK293T cells were transfected with the indicated plasmids and incubated with 1 μM PAL-CRID3, unless indicated otherwise, and subsequently irradiated. After cell lysis, click chemistry was performed, and lysates were assayed by TAMRA imaging and by immunoblot analysis with the indicated antibodies. CAPS, cryopryin-associated periodic syndrome; CRID, Cytokine Release Inhibitory Drug; HD, helical domain; HEK, human embryonic kidney; LRR, leucine-rich repeat; NBD, nucleotide-binding domain; NLR, NBD- and LRR-containing; NLRP3, NLR family, pyrin-domain–containing 3; NOD, nucleotide-binding oligomerization domain; PAL, photoaffinity labeling; PYD, Pyrin domain; TAMRA, 5-carboxytetramethylrhodamine; WB, western blot; WHD, winged helix domain.</p
sj-docx-1-pal-10.1177_08258597221086767 - Supplemental material for Virtual Reality Exposure Therapy in Palliative Care: A Case Series
No full textSupplemental material, sj-docx-1-pal-10.1177_08258597221086767 for Virtual Reality Exposure Therapy in Palliative Care: A Case Series by A. Seiler, M. Schettle, M. Amann, Sophie Gaertner, Stefan Wicki, S.M. Christ, G. Theile, M. Feuz, C. Hertler, and D. Blum in Journal of Palliative Care</p
sj-docx-1-pal-10.1177_08258597221131658 - Supplemental material for Do Socioeconomic Factors Influence Knowledge, Attitudes, and Representations of End-of-Life Practices? A Cross-Sectional Study
No full textSupplemental material, sj-docx-1-pal-10.1177_08258597221131658 for Do Socioeconomic Factors Influence Knowledge, Attitudes, and Representations of End-of-Life Practices? A Cross-Sectional Study by A. Bérubé, D. Tapp, S. Dupéré, A. Plaisance, G. Bravo, J. Downar and V. Couture in Journal of Palliative Care</p
Vitamin D and endocrine disorders: routine laboratory diagnostic implications
No full text: The role of vitamin D in calcium-phosphorus metabolism regulation is the most highlighted, nonetheless there is enormous literature on the extra-skeletal effects of vitamin D, and lately new insight into the role of vitamin D in endocrine disease mechanisms has seen light of day. The present narrative review gives an overview of the proposed roles of vitamin D in the etiology of Hashimoto's thyroiditis, Grave's disease, Addison's disease and primary hyperthyroidism. The implications as pertaining to the routine laboratory practice are readily applicable to this patient group as well, and do not pose any additional challenge
sj-docx-1-pal-10.1177_08258597231170836 - Supplemental material for Cancer Decedents’ Hospital End-of-Life Care Documentation: A Retrospective Review of Patient Records
No full textSupplemental material, sj-docx-1-pal-10.1177_08258597231170836 for Cancer Decedents’ Hospital End-of-Life Care Documentation: A Retrospective Review of Patient Records by L. Russell, R. Howard, M. Street, C. E. Johnson, D. Berry, E. Flemming-Judge, S. Brean, L. William and J. Considine in Journal of Palliative Care</p
SEM images of (A) magnetite nanoparticles magnified 70,000×; (B) PAL-CLEAs magnified 50,000×; (C) HM-PAL-CLEAs magnified 50,000×; as well as LCSM images of (D) magnetite nanoparticles with fluorescamine treatment and (E) HM-PAL-CLEAs with fluorescamine treatment.
No full text<p>SEM images of (A) magnetite nanoparticles magnified 70,000×; (B) PAL-CLEAs magnified 50,000×; (C) HM-PAL-CLEAs magnified 50,000×; as well as LCSM images of (D) magnetite nanoparticles with fluorescamine treatment and (E) HM-PAL-CLEAs with fluorescamine treatment.</p
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
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