1,721,067 research outputs found
Celiac Disease and HLA Molecular Typing
Full text linkThis article is focused on the genetic characteristics (HLA-DQ2 and HLA-DQ8) that predispose to a risk for celiac disease. The diagnosis of celiac disease is based on the
search for specific serum antibodies and on histological analysis of intestinal biopsies. The genetic test for the detection of HLA-DQ2 and HLA-DQ8 proteins could be used as a preliminary investigation for subjects for which celiac disease is suspected. This would allow to extend the serological and endoscopic analyzes only to genetically
predisposed subjects
PLANT COPPER-AMINE OXIDASES
No full textIn this review, the widely distributed plant copper-amine oxidases are described. The purification procedures, molecular features, substrate specificities, inhibitors, the stoichiometry of the catalysed reaction, spectroscopic features, the prosthetic groups and reaction mechanisms, are all reviewed
Molecular Analysis of a Copper- and Zinc-Containing Superoxide Dismutase Gene Isolated From the Latex of Euphorbia Characias: Another Piece in the Molecular Puzzle of Euphorbiaceae Latex Proteins
No full textOxidation of spermine by an amine oxidase from lentil seedlings
No full textSpermine is a substrate of lentil (Lens culinaris) seedling amine oxidase and the oxidation products are reversible inactivators of the enzyme. The spermine is oxidized at the terminal amino groups to a dialdehyde: 2 moles of hydrogen peroxide and 2 moles of ammonia per mole of spermine are formed. The pH optimum of the enzyme with spermine is 7.9 in Tl-HCl buffer; the K(m) value is 4.4. 10(-4) molar, similar to that found with other substrates (putrescine and spermidine)
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