1,721,124 research outputs found

    [Diet manipulations and nickel sulphate-induced contact dermatitis evaluated in 24 cases]

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    The wide distribution of nickel in the environment as well as in animal and vegetable foods has led a large number of authors to investigate the oral absorption of nickel. The aim of this study was to evaluate the effect of a free-nickel diet in 24 patients affected by nickel sulphate-induced contract dermatitis. The diagnosis was made on the basis of their past history and of Patch test. A complete remission of symptoms was obtained with a nickel-free diet for two months; Patch test became partial negative in 50% of patients and completely negative in 33%. In conclusion our results confirm the relationship between nickel-induced dermatitis and oral nickel absorption and suggest that diet manipulations can be useful in cases of refractory skin manifestations

    The folate binding proteins

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    Folates are essential molecules for cell life and, not surprisingly, their transport in biological fluids and their transfer to cells are finely regulated. Folate binding proteins play a major role in this regulation. This paper will review our knowledge on these proteins and examine the most recent advances in this field

    [The efficacy of nedocromil sodium in light or moderate allergic bronchial asthma]

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    Inhaled nedocromil sodium was administered 4 times a day for 8 weeks to 34 patients (20 males and 14 females) with mild to moderate allergic asthma to grass pollen. The study was conducted during the pollen season and patients were allowed extra medication only with beta 2 adrenergic drugs. On a diary card patients had to report daily variation of peak expiratory flow rate, severity and number of asthma attacks, severity of cough and use of bronchodilators. At the end of the study we observed a statistically significant improvement of all the parameters considered. No side effects were reported. Nedocromil sodium is therefore a useful and safe drug for the treatment of mild and moderate allergic asthma

    [Safety of azithromycin in patients allergic to penicillin and cephalosporin]

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    We have evaluated the safety of a new antibiotic, azithromicin, in 48 patients with allergy to penicillin and/or to cephalosporin. Diagnosis of allergy was based on clinical history, skin test and detection of serum specific IgE. The most common symptoms were urticaria, oedema, pruritus, oral aphthosis. Azithromicin was administered at the increasing dosage of 100-200-300 and 400 mg every 2 days. Our patients did not show any reaction to azithromicin. This antibiotic is therefore a valid alternative to penicillin and/or cephalosporin in patients allergic to these two drugs
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