1,187 research outputs found
Handwritten note by Judge Michael J. Roche
No full textNote by United States District Judge Michael J. Roche: "Filed July 2, 1943 In the above-entitled cause it appearing upon the face of the petition that petitioner is not entitled to a writ of habeas corpus, and it further appearing that she has not exhausted her administrative remedies under the provisions of Executive Order No. 9102 (7 Fed. Reg. 2165) and the regulations promulgated thereunder, IT IS THEREFORE ordered that the petition for a write of habeas corpus be, and the same is, hereby denied, dated: July 2, 1943." Note is written on the back of a document titled "Statement of Oswald Garrison Villard on Chinese Exclusion before the H. R. Committee on Immigration and Naturalization on May 20, 1943."The ACLU-Northern California case file records contain legal documents and correspondence pertaining to the case Ex parte Mitsuye Endo (1944), in which the United States Supreme court unanimously ruled that the federal government could not indefinitely detain United States citizens who were loyal to the government. Files include documents related to the Gordon Hirabayashi Supreme Court case Hirabayashi v. United States
Visit from Peter Roche
No full textThe Department of Sociology would like to apply for a grant to bring to our campus Professor Peter Roche de Coppens for two full days. Professor Roche de Coppens is a Professor of Sociology, Anthropology, and Psychotherapy atEast Stroudsburg University and Adjunct Professor of Education at McGill University in Montreal. He is the author of many books in English, French, and ltalian. Dr. Roche de Coppens has lectured at many universities and research centers around the world. He has trained under Pitirim Sorokin, founder of the sociology department at Harvard University, and Roberto Assagioli of Florence, Italy. In addition to his University work Dr. Roche de Coppens has developed his own radio program, Tools for Living and TV program, Soul Sculpture in Pennsylvania. Since 1987 he has acted as a lecturer and consultant for the United Nations. Professor Roche de Coppens during the last 45 years has tried to integrate the finding and insights of social science with spirituality and holistic health\u2
Bronchial mucosal manifestations of atopy: a comparison of markers of inflammation between atopic asthmatics, atopic nonasthmatics and healthy controls
No full textWe studied the role of atopy, as defined by positive skin tests to common inhalant allergens, in allergic bronchial inflammation. Endobronchial biopsies were taken via the fibreoptic bronchoscope in 13 symptomatic atopic asthmatics, 10 atopic nonasthmatics, and 7 normals. The numbers of mast cells, identified in the submucosa by immunohistochemistry using the AA1 monoclonal antibody against tryptase, were no different between the three groups, but electron microscopy showed that mast cell degranulation, although less marked in atopic nonasthmatics, was a feature of atopy in general. The numbers of eosinophils, identified by immunohistochemical staining using the monoclonal anti-eosinophil cationic protein antibody, EG2, were greatest in the asthmatics, low or absent in the normals and intermediate in the atopic nonasthmatics. In both atopic groups eosinophils showed ultrastructural features of degranulation. Measurements of subepithelial basement membrane thickness on electron micrographs showed that the collagen layer was thickest in the asthmatics, intermediate in the atopic nonasthmatics and thinnest in the normals. The results suggest that airways eosinophilia and degranulation of eosinophils and mast cells, as well as increased subepithelial collagen deposition, are a feature of atopy in general and suggest that the degree of change may determine the clinical expression of this immune disorder
Airway inflammation and atopic asthma: a comparative bronchoscopic investigation
No full textFlexible fibre-optic bronchoscopy under local anaesthesia has been used to investigate the cellular airway events in atopic asthma. The findings have been compared to those from atopic individuals without asthma and non-atopic healthy controls, in an attempt to discern those changes relevant to clinical disease expression. Immunohistochemical and electron-microscopic analyses of airway biopsies identified that an atopic diathesis is associated with tissue eosinophil infiltration and mast cell degranulation. The eosinophilia was greatest in those atopic individuals with asthma. Flow-cytometric analysis of airway lavage revealed significantly enhanced T lymphocyte activation in clinical asthma. These findings are consistent with the hypothesis that T lymphocyte activation, through cytokine release, amplifies the tissue eosinophilia in asthma and that this combination is associated with clinical disease expression
Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry
No full textWe have used fiberoptic bronchoscopy to obtain endobronchial biopsies in which mast cells and eosinophils were enumerated using monoclonal antibodies directed against mast cell tryptase (AA1) and the eosinophil cationic protein (EG2). Eleven symptomatic atopic asthmatics treated with beta 2-agonists alone and six normal subjects were studied. Over a period of 2 wk prior to bronchoscopy, patients recorded asthma symptom scores, bronchodilator usage, and twice-daily peak expiratory flow. Five days before bronchoscopy, methacholine responsiveness was assessed. Two biopsies were taken from the subcarinae, one of which was processed into araldite for immunostaining by the streptavidin biotin immunoperoxidase method and the other into Spurr resin for electron microscopy. The number of AA1 staining mast cells present in the bronchial mucosa was not significantly different in the epithelium or submucosa between the asthmatic and the normal subjects. However, in the biopsies from asthmatics, there were significantly greater numbers of EG2-staining eosinophils in the epithelium (median, 1.2/mm versus zero; p less than 0.005) and in the submucosa (median, 50/mm2 versus 1/mm2; p less than 0.001). Electron microscopy showed morphologic features of mast cell and eosinophil degranulation in the asthmatics. No correlation could be established between mast cell or eosinophil numbers and indices of disease activity of PC20 methacholine, which points to the complexity of mechanisms responsible for the symptoms and the airway hyperresponsiveness of asthma
Multiple iterations : mapping the trace
No full textThis paper explores the concept that individual dancers leave traces in a choreographer’s body of work and similarly, that dancers carry forward residue of embodied choreographies into other working processes. This presentation will be grounded in a study of the multiple iterations of a programme of solo works commissioned in 2008 from choreographers John Jasperse, Jodi Melnick, Liz Roche and Rosemary Butcher and danced by the author. This includes an exploration of the development by John Jasperse of themes from his solo into the pieces PURE (2008) and Truth, Revised Histories, Wishful Thinking and Flat Out Lies (2009); an adaptation of the solo Business of the Bloom by Jodi Melnick in 2008 and a further adaptation of Business of the Bloom by this author in 2012. It will map some of the developments that occurred through a number of further performances over five years of the solo Shared Material on Dying by Liz Roche and the working process of the (uncompleted) solo Episodes of Flight by Rosemary Butcher. The purpose is to reflect back on authorship in dance, an art form in which lineages of influence can often be clearly observed. Normally, once a choreographic work is created and performed, it is archived through video recording, notation and/or reviews. The dancer is no longer called upon to represent the dance piece within the archive and thus her/his lived presence and experiential perspective disappears. The author will draw on the different traces still inhabiting her body as pathways towards understanding how choreographic movement circulates beyond this moment of performance. This will include the interrogation of ownership of choreographic movement, as once it becomes integrated in the body of the dancer, who owns the dance? Furthermore, certain dancers, through their individual physical characteristics and moving identities, can deeply influence the formation of choreographic signatures, a proposition that challenges the sole authorship role of the choreographer in dance production. This paper will be delivered in a presentation format that will bleed into movement demonstrations alongside video footage of the works and auto-ethnographic accounts of dancing experience. A further source of knowledge will be drawn from extracts of interviews with other dancers including Sara Rudner, Rebecca Hilton and Catherine Bennett
Die Schreibweisen der Sophie von La Roche
No full textInternational audienceDer Beitrag führt exemplarisch die Verwendung von drei unterschiedlichen Schreibweisen durch Sophie von La Roche (1730–1807) vor. Während das Komisch‐Parodistische vor allem zu Beginn ihrer Karriere greifbar ist, ist das lebenslange Festhalten am Moralisch‐Didaktischen und am Hybriden als typisches Kennzeichen ihres Schreibens, aber auch als eine Ursache für ihre immer stärkere Marginalisierung im literarischen Betrieb des ausgehenden 18. Jahrhunderts zu begreifen.The article analyses the use of three different modes of writing (‘Schreibweisen’) by Sophie von La Roche (1730–1807). It is argued that at the beginning of her literary career La Roche wrote in a comic‐parodistic style, while moral‐didactic and hybrid writing are typical characteristics of her entire œuvre. La Roche's use of moral‐didactic and hybrid modes needs to be seen as one of the reasons for the growing marginalisation of the author at the end of the eighteenth century
Slow Dynamics in turbulent Helium flows
No full textThe presence of slow dynamics is a recurrent feature of many turbulent flows. This behaviour can be created by instabilities of the mean flow or by other mechanisms. In this work we analyze the behavior of a highly turbulent Helium flow (maximum Reynolds number Re=10^8, with a Reynolds based on the Taylor microscale Re_\lambda=2000). We have performed velocity measurements using home-made Pitot tubes. The analysis of the data series reveals that below the injection frequencies there are different dynamical regimes with time scales two orders of magnitude below the injection scale
A Short Proof of a Near-Optimal Cardinality Estimate for the Product of a Sum Set
No full textIn this note it is established that, for any finite set A of real numbers, there exist two elements a, b from A such that |(a + A)(b + A)| > c|A|^2 / log |A|, where c is some positive constant. In particular, it follows that |(A + A)(A + A)| > c|A|^2 / log |A|. The latter inequality had in fact already been established in an earlier work of the author and Rudnev, which built upon the recent developments of Guth and Katz in their work on the Erdös distinct distance problem. Here, we do not use those relatively deep methods, and instead we need just a single application of the Szemerédi-Trotter Theorem. The result is also qualitatively stronger than the corresponding sum-product estimate from the paper of the author and Rudnev, since the set (a + A)(b + A) is defined by only two variables, rather than four. One can view this as a solution for the pinned distance problem, under an alternative notion of distance, in the special case when the point set is a direct product A x A. Another advantage of this more elementary approach is that these results can now be extended for the first time to the case when A is a set of complex numbers
Invited lecture: activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma
No full textBackground: A recent NIH Workshop and an ERS Task Force concluded that more work was needed to understand mechanisms of severe and chronic asthma. This report describes a series of studies that identify aberrant epithelial mesenchymal signalling in the airways as an important event in maintaining inflammation and driving remodelling in response to environmental injury. Methods: Immunohistochemistry, genotyping and functional studies conducted on cultured asthmatic cells and mucosal biopsies were used to identify biochemical pathways involved in epithelial injury and repair in asthma and their relationship to disease severity. Results: Our findings suggest that the asthmatic state results from an interaction between a susceptible epithelium and Th-2-mediated inflammation to alter the communication between the epithelium and the underlying mesenchyme - the epithelial mesenchymal trophic unit - leading to disease persistence, airway remodelling and refractoriness to corticosteroid treatment. Conclusions: Asthma is more than an inflammatory disorder, but requires engagement of important signalling pathways involved in epithelial repair and tissue remodelling. These pathways involving EGFRs and TGF-Rs provide targets against which to develop novel therapies for chronic asthma
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