1,720,999 research outputs found
Urine retention due to intra-spinal cord injection of colchicine: Therapeutic effect of bremazocine, Nerve Growth Factor and Monosialoganglioside.
No full textBremazocine prevents urine retention due to intra-spinal cord injection of colchicine: role of K and sigma receptors.
No full textRole of sigma, phencyclidine and NMDA receptors in urine retention due to intra-spinal cord injection of colchicine in rats.
No full textNerve Growth Factor and monosialoganglioside (GM1) administration improves the recovery of bladder function in a rat model of colchicine-induced urine retention.
No full textEffects of the cannabinoid antagonist SR 141716 on sexual and motor behaviour in receptive female rats
No full textThe aim of the present study was to investigate the effect of the cannabinoid antagonist/inverse agonist SR 141716 (SR) on the receptive behaviour and sexual motivation of female rats. Partner preference, receptivity and proceptivity were evaluated in ovariectomized female rats primed with oestrogen and progesterone and administered SR (1 or 2.5 mg/kg, i.p.) 20 min prior to testing. In the partner preference test, a reduced interest in both stimulus animals (a sexually active male and an ovariectomized hormone-primed female) was detected in rats treated with SR at both doses, but no effect on preference score was observed. In the receptivity test, pronounced reductions in lordosis quotient, lordosis rating and in the percentage of receptive females were found in SR-treated rats compared with control rats. Proceptive behaviours were not significantly affected by either dose of SR. In addition, we explored the behavioural effects induced by SR in female rats using the open field test. Only at the higher dose (i.e. 2.5 mg/kg) did SR markedly increased grooming and scratching behaviour. The results demonstrate the ability of SR to reduce female sexual receptivity, but not sexual motivation. The reduction does not seem strictly related to the motor alterations induced by the cannabinoid antagonist
Effects of pre and postnatal exposure to methylmercury on the rat brain development and functions.
No full textPrenatal exposure to methylmercury during late gestation affects cerebral opiatergic system in rat offspring.
No full textEvidence that chronic treatment with flunitrazepam increases cerebral NMDA-glutamate receptors.
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