150 research outputs found
A new way to look at mesoscale zooplankton distributions: an application at the Antarctic Polar Front
No full textDuring the austral summer of 1996 an intensive multidisciplinary survey was carried out in the Antarctic Polar Front. In this paper, we examine the relationship between hydrographic features and the acoustic backscatter signal from a vessel-mounted acoustic Doppler current profiler. We introduce two new analysis methods: mapping of depth-integrated scattering cross section and a model of the vertical zooplankton distribution through idealised population dynamics. Three distinct layers are characterised by a different balance between diel migration behaviour and direct/indirect forcing by mesoscale physical processes in the ocean
Silvia Strass, Le funzioni degli ύπηρέται nell'Egitto greco e romano
No full textMelaerts Henri. Silvia Strass, Le funzioni degli ύπηρέται nell'Egitto greco e romano. In: L'antiquité classique, Tome 68, 1999. p. 504
Preoperative radiotherapy in patients with primary retroperitoneal sarcoma: EORTC-62092 trial (STRASS) versus off-trial (STREXIT) results
No full textObjective: The aim of the present study was to compare the effect of radiotherapy (RT) on abdominal recurrence-free survival (ARFS) in patients with primary retroperitoneal sarcoma treated in the EORTC-STBSG-62092 (STRASS) phase 3 randomized controlled trial (STRASS cohort) and off-trial (STREXIT cohort) and to pool STRASS and STREXIT data to test the hypothesis that RT improves ARFS in patients with liposarcoma.Background: The STRASS trial did not show any difference in ARFS between patients treated with preoperative radiotherapy+surgery (RT+S) versus surgery alone (S).Methods: All consecutive adult patients not enrolled in STRASS and underwent curative-intent surgery for a primary retroperitoneal sarcoma with or without preoperative RT between 2012 and 2017 (STRASS recruiting period) among ten STRASS-recruiting centres formed the STREXIT cohort. The effect of RT in STREXIT was explored with a propensity score (PS)-matching analysis. Primary endpoint was ARFS defined as macroscopically incomplete resection or abdominal recurrence or death of any cause, whichever occurred first.Results: STRASS included 266 patients, STREXIT included 831 patients (727 after excluding patients who received preoperative chemotherapy, 202 after 1:1 PS-matching). The effect of RT on ARFS in STRASS and 1:1 PS-matched STREXIT cohorts, overall and in patients with liposarcoma, was similar. In the pooled cohort analysis, RT administration was associated with better ARFS in patients with liposarcoma [N=321, hazard ratio (HR), 0.61; 95% confidence interval (CI), 0.42–0.89]. In particular, patients with well-differentiated liposarcoma and G1-2 dedifferentiated liposarcoma (G1-2 DDLPS, n=266) treated with RT+S had better ARFS (HR, 0.63; 95% CI, 0.40–0.97) while patients with G3 DDLPS and leiomyosarcoma had not. At the current follow-up, there was no association between RT and overall survival or distant metastases-free survival.Conclusions: In this study, preoperative RT was associated with better ARFS in patients with primary well-differentiated liposarcoma and G1-2 DDLPS.Experimentele farmacotherapi
Das Wallfahrtsbuch des Hermannus Künig von Vach und die Pilgerreisen der Deutschen nach Santiago de Compostela /
No full textFacsimile reproduction of the 1495 ed. of Künig's poem Die walfart und Strass zu sant Jacob: [24] p. at end.Includes bibliographical references.Mode of access: Internet
Process challenges of the STRASS technique to increase the electron mobility in advanced FD-SOI nMOSFETs
No full textInternational audienceTo improve the I/I performance of transistors, it is crucial to significantly increase the charge carrier mobility in the channels of field-effect transistors. Tensile stress/strain is known to improve the electron mobility in the channels of nMOS-FETs. This paper focuses on the STRASS (Strained Silicon by Top Recrystallization of Amorphized SiGe on SOI) process for introducing tensile stress into the silicon channel of the next-generation n-type Fully Depleted Silicon-On-Insulator (FD-SOI) devices. This technique is challenging, especially for very thin silicon film channels (e.g., less than 10 nm), where the controlled creation of a buried amorphous layer by ion implantation is difficult. By carefully optimizing the individual process steps of the STRASS technique, we have achieved the transfer of up to 1.6 GPa of tensile stress into the silicon of blanket SOI wafers
Summary Report of The First International Competition on Computational Models of Argumentation
No full textComputational models of argumentation are an active research discipline within Artificial Intelligence that has grown since the beginning of the 1990s (Dung 1995).
While still a young field when compared to areas such as SAT solving and Logic Programming, the argumentation community is very active, with a conference series (COMMA, which began in 2006) and a variety of workshops and special issues of journals. Argumentation has also worked its way into a variety of applications. For example, Williams et al. (2015) described how argumentation techniques are used for recommending cancer treatments, while Toniolo et
al. (2015) detail how argumentation-based techniques can support critical thinking and collaborative scientific inquiry or intelligence analysis.
Many of the problems that argumentation deals with are computationally difficult, and applications utilising argumentation therefore require efficient solvers. To encourage this line of research, we organised the First International
Competition on Computational Models of Argumentation (ICCMA), with the intention of assessing and promoting state of the art solvers for abstract argumentation problems, and to identify families of challenging benchmarks for
such solvers.
The objective of ICCMA’15 is to allow researchers to compare the performance of different solvers systematically on common benchmarks and rules. Moreover, as witnessed by competitions in other AI disciplines such as planning and SAT solving, we see ICCMA as a new pillar of the community which provides information and insights on the current state of the art, and highlights future
challenges and developments.
This article summarises the first ICCMA held in 2015 (ICCMA’15). In this competition, solvers were invited to address standard decision and enumeration problems of abstract argumentation frameworks (Dunne and Wooldridge 2009).
Solvers’ performance is evaluated based on their time taken to provide a correct solution for a problem; incorrect results were discarded. More information about the competition, including complete results and benchmarks, can be found on the ICCMA website
India Orientalis [cartographic material] : cuius nobilior pars sunt duo ista quasi ingentia totius Asiæ promontaria in Oceanum versus Meridiem projecta, cum suis insulis /
No full textMap of Southeast Asia, India, China, Japan and small part of Continentis Australis with relief shown pictorially.; Plate from: Geographisch Handtbuch / M. Quad. Coln am Rein : bey Johan Buxemacher kunstdrucker vff. s. Maximini strass daselbst, 1600.; Latin text on verso: India (p. 6).; Phillips, 411.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.map-rm306
New research strategies in retroperitoneal sarcoma. The case of TARPSWG, STRASS and RESAR: making progress through collaboration
No full textPurpose of reviewRetroperitoneal sarcoma (RPS) is a rare disease, and until recently, its natural history and outcome were poorly understood. Recently, collaborations between individual centers have led to an unprecedented collection of retrospective and prospective data and successful recruitment to the first randomized trial as described here.Recent findingsA debate about the beneficial role of extended surgery in RPS triggered an initial collaboration between Europe and North America, the TransAtlantic RetroPeritoneal Sarcoma Working Group (TARPSWG). This collaboration has been instrumental in harmonizing the surgical approach among expert centers, characterizing the pattern of postresection failure of the different histological subtypes, identifying new ways to stage RPS and testing the role of preoperative radiotherapy in a randomized fashion (STRASS-1 study). The collaboration has now expanded to include centers from Asia, Australia and South America. A prospective registry has been started and a new randomized trial, STRASS-2, is in preparation to analyze the role of neoadjuvant chemotherapy for high-grade liposarcoma and leiomyosarcoma of the retroperitoneum.SummaryCollaboration is critical to study a rare disease like RPS. Both retrospective and prospective data are useful to improve knowledge, generate hypotheses and build evidence to test, whenever possible, in clinical trials.Biological, physical and clinical aspects of cancer treatment with ionising radiatio
Évaluation de la calprotectine comme facteur prédictif de rechute dans la polyarthrite rhumatoïde, lors de la décroissance des anti-TNF-alpha : une analyse post-hoc de l’étude STRASS
No full textThe search for prognostic tools for the biological treatment tapering in patients with rheumatoid arthritis (RA), is a major challenge to decide their management. Our objective was to determine whether serum calprotectin concentration at baseline was associated with relapse within 18 months, in patients with rheumatoid arthritis in sustained remission during TNF-blocker tapering. We included patients presenting rheumatoid arthritis in sustained DAS28 remission, treated with Etanercept or Adalimumab, from the spacing randomization arm of STRASS study. Serum calprotectin concentration was assessed in patients by enzyme-linked immunosorbent assay at baseline. Disease activity was assessed every 3 months in each center by a rheumatologist. We assessed calprotectin concentration in 61 serums from patients of STRASS spacing arm, and 54 were included in per protocol analysis. No significant association was found in the per protocol analysis between the occurrence of at least one relapse within 18 months and baseline calprotectin concentration in spacing arm, (1309 ng/mL [879;2273] vs 1011 ng/mL [605;2112] in patients without relapse, p=0,1396). There was neither significant association between calprotectin concentration and at least one relapse in 18 months with multivariable model, (OR 0.99 (95% IC 0.99 to 1.00), p=0.929). Serum calprotectin concentration in patient with RA in remission with TNF-blocker does not predict relapse during Etanercept and Adalimumab tapering.La recherche d’outils pronostiques de la décroissance des biothérapies chez les patients atteints de polyarthrite rhumatoïde (PR), est un enjeu majeur pour guider leur prise en charge. Notre objectif était de déterminer si la concentration sérique initiale en calprotectine était associée à un risque de rechute dans les 18 mois, chez les patients atteints de PR en rémission prolongée, débutant une décroissance de leur anti-TNFα. Nous avons inclus dans cette étude, les patients présentant une PR en rémission prolongée selon le DAS28, traités par Etanercept ou Adalimumab, issus du bras de randomisation «espacement thérapeutique» de l'étude STRASS. La concentration sérique de calprotectine était évaluée chez les patients par un test Enzyme-linked immunosorbent assay (ELISA) avant de débuter la décroissance. L'activité de la maladie était évaluée tous les 3 mois dans chaque centre par un rhumatologue. Le taux de calprotectine initial a été dosé dans le sérum de 61 patients du bras «espacement thérapeutique» de l’étude STRASS, et 54 ont été inclus dans l'analyse per protocole. Cet analyse n'a révélé aucune association significative entre la survenue d'au moins une rechute dans les 18 mois et la concentration de calprotectine initiale dans le bras «espacement thérapeutique», (1309 ng/mL [879; 2273] versus 1011 ng/mL [605; 2112] chez les patients n’ayant pas présenté de rechute, p = 0,1396). Il n'y avait pas non plus d'association significative entre la concentration de calprotectine et la survenue d’au moins une rechute en 18 mois en utilisant un modèle multivarié, (OR 0,99 (95% IC 0,99 à 1,00), p = 0,929). Le taux de calprotectine sérique initial chez un patient atteint de PR en rémission prolongée sous anti-TNFα ne permet pas de prédire son risque de rechute lors de la décroissance progressive de l’Etanercept ou de l'Adalimumab
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