276 research outputs found

    Le mani di Jacek Woszczerowicz, attore “di composizione” [An actor of composition. Jacek Woszczerowicz's hands]

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    "The article aims to draw attention back to the art of Jacek Woszczerowicz, once a well-known and beloved Polish actor. It focuses on his peculiar acting style by analyzing two adaptations of stage dramas and a documentary of a theatrical masterpiece Richard III (1960). In particular, the author highlights Woszczerowicz’s work on gesture and the role played by hands in building characters. This brief survey will lead us to re-discover the deep process of cognition and experience realized dramatically by the artist and to understand why Jan Kott considered him “the first contemporary Shakespeare”, while Jerzy Grotowski praised him as the greatest “actor of composition”.

    Dual role of VEGF in pretreated experimental ePTFE arterial grafts

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    Background. Lack of endothelialization and abnormal smooth muscle cell (SMC) growth adversely affect the outcome of vascular synthetic grafts. The aims of our study were to investigate how a coating of extracellular matrix (ECM) and vascular endothelial growth factor (VEGF) might affect the endothelialization rate, smooth muscle cells (SMC) proliferation, and myointimal hyperplasia in experimental arterial ePTFE grafts. Methods. In each of 30 male Lewis rats, a 1-cm-long ePTFE graft was inserted at the level of the abdominal aorta. Animals were randomized in five groups (six animals each): groups A and A1 received ePTFE grafts coated with a synthetic extracellular matrix (growth factor-reduced matrigel) containing VEGF; groups B and B1 received ePTFE grafts coated with synthetic ECM; and group C received ePTFE grafts alone. The grafts were explanted at 30 days from surgery for immunohistochemical analysis. Results. Both endothelialization rate and myointimal hyperplasia were augmented in group A versus groups B and C, and these findings were statistically significant. SMC density resulted significantly higher in group A versus groups B and C, and this was associated with an altered expression of bFGF and TGF beta. Conclusions. Pretreating ePTFE grafts with synthetic ECM and VEGF results in better endothelialization, but also in undesired higher SMC density and myointimal hyperplasia. (c) 2005 Elsevier Inc. All rights reserved
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