239 research outputs found
Supplementary_data_(1) - Top cited articles on ameloblastoma: A bibliometric analysis
No full textSupplementary_data_(1) for Top cited articles on ameloblastoma: A bibliometric analysis by Shailesh M Gondivkar, Sachin C Sarode, Amol R Gadbail, Rima S Gondivkar, Gargi S Sarode, Nilookumari Choudhary, and Shankargouda Patil in Translational Research in Oral Oncology</p
Dental caries and Dental Anomalies in children with cleft Lip and cleft Palate in Bengaluru city, India
No full textABSTRACT
Aim
The aim of this study was to assess the association of dental caries and dental anomalies among 5- to 15-year-old children with cleft lip and cleft palate.
Materials and methods
A cross-sectional study was conducted among 500 children with cleft lip and/or cleft palate and 500 children without cleft of the age group 5 to 15 years. The clinical examination was carried out using decayed, missing, and filled teeth (DMFT) by Klein Plamer and Knutson, and dmft by Grubbel and 1997 World Health Organization (WHO) pro forma.
Results
The results showed a statistically significant increase in the prevalence of dental caries in children with cleft lip and/or cleft palate. The mean DMFT was found to be significantly higher in operated children than in the children who were not operated. Other dental abnormalities included an increased frequency of enamel hypoplasia (p < 0.001), hyperdontia (p < 0.014), anterior, unilateral and bilateral cross-bite (p < 0.001), and open bite (p < 0.001).
Conclusion
The results of this study show that children with cleft have higher prevalence of dental anomalies than the normal children. With increased occurrence of hypoplasia in children with cleft, reduced access for cleaning upper anterior teeth after surgical repair leads to poor oral hygiene status, leading to increased risk to dental caries.
Clinical significance
Given the high caries experience among the children with cleft lip and cleft palate, it is necessary to advocate a more rigorous approach to the prevention of dental disease in these high-risk children. They should therefore, be subjected to regular checkups, oral hygiene advice, diet advice, appropriate fluoride supplementation, and, when required, appropriate referral for secondary care.
How to cite this article
Kamble S, Hiremath SS, Puranik MP, Gaikwad R, Biradar A, Gadbail AR, Sarode SC, Sarode GS, Patil S. Dental Caries and Dental Anomalies in Children with Cleft Lip and Cleft Palate in Bengaluru City, India. World J Dent 2017;8(4):304-308.
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Molecular heterogeneity in adjacent cells in triple-negative breast cancer
No full textMichael L Huebschman,1 Nancy L Lane,1 Huaying Liu,1 Venetia R Sarode,2 Judith L Devlin,1 Eugene P Frenkel1,3 1Harold C Simmons Comprehensive Cancer Center, 2Department of Pathology, 3Division of Hematology-Medical Oncology, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA Purpose: This study interrogates the molecular status of individual cells in patients with triple-negative breast cancers and explores the molecular identification and characterization of these tumors to consider the exploitation of a potential-targeted therapeutic approach. Patients and methods: Hyperspectral immunologic cell by cell analysis was applied to touch imprint smears obtained from fresh tumors of breast cancer patients. Results: Cell by cell analysis confirms significant intratumoral molecular heterogeneity in cancer markers with differences from polymerase chain reaction marker reporting. The individual cell heterogeneity was recognized in adjacent cells examined with panels of ten molecular markers in each single cell and included some markers that are considered to express “stem-cell” character. In addition, heterogeneity did not relate either to the size or stage of the primary tumor or to the site from within the cancer. Conclusion: There is a very significant molecular heterogeneity when “adjacent cells” are examined in triple-negative breast cancer, thereby making a successful targeted approach unlikely. In addition, it is not reasonable to consider that these changes will provide an answer to tumor dormancy. Keywords: hyperspectral, cancer stem cells, CSC, CD44, CD24, ALDH1, uPAR, CD133, Her-
Interplay between water uptake, ion interactions, and conductivity in an e-beam grafted poly(ethylene-co-tetrafluoroethylene) anion exchange membrane
No full textWe demonstrate that the true hydroxide conductivity in an e-beam grafted poly(ethylene-co-tetrafluoroethylene) [ETFE] anion exchange membrane (AEM) is as high as 132 mS cm(-1) at 80 °C and 95% RH, comparable to a proton exchange membrane, but with very much less water present in the film. To understand this behaviour we studied ion transport of hydroxide, carbonate, bicarbonate and chloride, as well as water uptake and distribution. Water uptake of the AEM in water vapor is an order of magnitude lower than when submerged in liquid water. In addition (19)F pulse field gradient spin echo NMR indicates that there is little tortuosity in the ionic pathways through the film. A complete analysis of the IR spectrum of the AEM and the analyses of water absorption using FT-IR led to conclusion that the fluorinated backbone chains do not interact with water and that two types of water domains exist within the membrane. The reduction in conductivity was measured during exposure of the OH(-) form of the AEM to air at 95% RH and was seen to be much slower than the reaction of CO2 with OH(-) as the amount of water in the film determines its ionic conductivity and at relative wet RHs its re-organization is slow
Potential Predictor of Tobacco Cessation among Factory Workers: A Baseline Data of Worksite Tobacco Cessation Programs in the Central Part of India
No full textABSTRACT
Aim
Our study aimed to evaluate the prevalence of tobacco use among factory workers and identify the predicting factors for quitting tobacco use.
Materials and methods
In this cross-sectional study, a total of 640 factory workers were included and divided into the quitter group and who had never quit the tobacco habit in the past. Data were collected by standardized and validated questionnaire pro forma, which comprised the demographic profile, smoking history, and Fagerström scale to check the nicotine dependence. Data were analyzed using descriptive analysis and Chi-squares test, whereas logistic regression was used to predict the factor for quitting the tobacco habit. All tests were applied using Statistical Package for the Social Sciences (SPSS) version 17.0.
Results
The mean age among the quitters was comparatively low than the never-quit group. Out of 640 participants, the majority of quitters and those who never quit were found to consume smokeless tobacco (232 [93.5]; 288 [73.5]). As per logistic regression analysis, gender of participants, age of starting tobacco use, and frequency of tobacco use can be considered as good predictors to quit smoking/chewing tobacco.
Conclusion
The present study found that participants in the quitter group were less dependent on tobacco, and these participants were more likely to quit smoking if behavioral support was provided at the early days of the quitting attempt.
Clinical significance
This study's result provides valuable insight into the current tobacco usage and potential predicting factors for quitting tobacco use among factory workers in India. These data can help in developing a policy for the implementation of tobacco cessation programs at the worksite.
How to cite this article
Gaikwad R, Bhowate R, Bajad P, Gadbail AR, Gondivkar S, Sarode SC, Sarode GS, Patil S. Potential Predictor of Tobacco Cessation among Factory Workers: A Baseline Data of Worksite Tobacco Cessation Programs in the Central Part of India. J Contemp Dent Pract 2017;18(11):1071-1077.
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Significance of cytologically normal endometrial cells in cervical smears from postmenopausal women
No full textOBJECTIVE: To determine the significance of cytologically normal endometrial cells in cervicovaginal (CV) smears from postmenopausal women over age 55 years. STUDY DESIGN: From January 1995 to January 1998, 220 women had CV smears demonstrating cytologically normal endometrial cells. The menopausal status, hormone replacement therapy (HRT) and information related to subsequent CV smears and endometrial sampling within 12 months of the initial diagnosis was recorded. RESULTS: Eighty-one of the 220 cases (36.8%) had histologic sampling of the endometrium. Thirty-four of 81 (42%) showed no endometrial pathology. Endometrial pathology was identified in 28 of 81 (34%), of which 19 were endometrial polyps (23.4%), 4 were endometrial hyperplasia (4.9%), 4 were endometrial carcinoma (4.9%) and 1 was a leiomyoma (1.2%). Nineteen (23.4%) were insufficient for diagnosis. Ninety-one of 220 women were on HRT, and 129 were not. In the group without HRT, endometrial disease was identified in 22/51 (43%) cases as compared to 6/30 (20%) in the group with HRT (P<.001). Endometrial carcinoma was identified in three (5.8%) cases and one (3.3%) case without and with HRT, respectively. CONCLUSION: Although the finding of normal endometrial cells in Pap smears from postmenopausal women was without any clinical significance in the majority of women in this study, in a small number it was associated with endometrial hyperplasia and carcinoma. Women who were not on HRT had a higher incidence of endometrial pathology
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