125 research outputs found
Li Fioretti di Sancto Francesco
No full textIl grande pannello, realizzato nel 1940 dal Laboratorio Artigiano Triestino su disegno di Anita Pittoni, venne esposto per la prima volta alla VII Triennale Internazionale d’Arte decorativa e fu il frutto del concorso indetto dall’Ente Triennale di Milano e dall’Enapi di Roma (il cui scopo era quello di indurre gli artisti a fornire disegni moderni d’arte applicata alle scuole e ai laboratori femminili di ricamo e merletto). Il concorso prevedeva che vi partecipassero 19 tende da esporre alle finestre dell’emiciclo del Palazzo delle Arti. Il tema risultava libero, uniche direttive da seguire: misure e tecniche. Anita Pittoni decise di illustrare in 8 riquadri la vita di San Francesco. Il manufatto reca iscrizioni in volgare umbro accompagnate da raffigurazioni dal carattere primitivo. Il risultato fu ottimale tant’è che il lavoro si aggiudicò la medaglia d’oro per il disegno e una menzione d’onore per il suo contributo all’Enapi. Alla Pittoni si deve l’invenzione di una nuova interpretazione delle tecniche della maglia e dell’uncinetto, usate sino ad allora per realizzare principalmente pizzi e merletti. Furono da lei adoperate per realizzare sofisticati tessuti d’arredamento. Alla mostra degli artisti triestini alla Permanente di Milano la Pittoni presentò, oltre al grande pannello, anche vari oggetti di moda femminile quali costumi per la spiaggia, mantelli, un abito estivo di rete gialla, una giacca di canapa, un costume da sera in rame, borsette, bandoliere, bottoni, tappeti ed altri accessori. Ciò che colpì delle creazioni di Anita fu la constatazione che era un’artista capace di creare forme e ritmi tessendo filati come altri usavano parole e suoni. Le parti figurative sono accompagnate da scritte ricamate che riportano alcuni passi tratti dai Fioretti di San Francesco. Nel primo riquadro si legge una parte tratta dal Capitolo 9 in cui San Francesco, essendo con fra Lione in un luogo dove non avevano libri e breviario col quale recitare le preghiere del mattutino, i due si accordarono affinché Fra Lione ripetesse quanto San Francesco diceva. San Francesco iniziò così: “O Signore mio del cielo e della terra, io ho commesso contro a te tante iniquità e tanti peccati, che al tutto son degno d’esser da te maledetto”. E frate Lione anziché rispondere come Francesco gli aveva indicato rispose con la frase ricamata sul pannello: “O frate Francesco, Iddio ti farà tale, che tra li benedetti tu sarai singolarmente benedetto”. Accanto a questa frase si può ammirare il ricamo decorato in cui San Francesco viene elevato da due figure angeliche. La grande tenda presenta una decorazione “a scacchiera”: alla parte scritta corrisponde una formella decorata e viceversa per quattro fasce orizzontali. Il ritmo delle due colonne è ulteriormente scandito dalla realizzazione, in senso verticale, di una sorta di rima incrociata (ABAB). La seconda formella illustra un passo tratto dal 16° Capitolo dei Fioretti in cui San Francesco, accogliendo gli inviti di Santa Chiara e San Silvestro di predicare a quante più genti possibili, iniziò a predicare anche agli uccelli. La terza formella scritta riprende nuovamente parte del Capitolo 9 caratterizzata dallo scambio di battute tra San Francesco e San Lione. Nella parte iconografica invece ritroviamo San Francesco circondato da fiori. Gli ultimi due riquadri, trattano un passo del 15° capitolo dei Fioretti. Quello illustrato a sinistra, si vede San Francesco in saio con di fronte Santa Chiara. La formella è impreziosita da un decoro, nella parte superiore, a motivo a stella, mentre nella parte inferiore, vi è un motivo decorativo floreale con degli uccellini. La parte scritta chiude invece il pannello decorativo nel quale sono riportate le parole di santa Chiara: “ed ella come figliuola di santa obbidienza avea risposto: “Padre, io sono sempre apparecchiata ad andare dovunque voi mi manderete”. Acquistato dall’Università degli Studi di Trieste nel 1951 è attualmente visibile nell’aula Magna della sede principale dell’Università.Pannello a velo, ricamo su tulleFirmato in basso a destra “Anita Pittoni”Edificio Centrale, Aula Magn
Constitutiones pontificiae et romanarum congregationum decisiones ad matrimonium tum constans tum etiam solutum canonice [et] civiliter spectantes : in tres tomos distributae /
No full textMode of access: Internet.Marca tip. en port.Error de pag., de p. 256 pasa a 259
Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors.
No full textc-Kit tyrosine kinase receptor and its ligand stem cell factor have multiple functions during development, whereas in adulthood they are mostly needed for stem cell (SC) maintenance and mast cell (MC) biology. c-Kit plays an essential tumor-cell-intrinsic role in many types of cancer, either providing the tumorigenic force when aberrantly activated or conferring stem-like features characterizing the most aggressive variants. A tumor-cell-extrinsic role occurs through c-Kit-dependent accessory cells (such as MCs) that infiltrate tumors and deeply influence their progression. c-Kit-targeted therapy with tyrosine kinase inhibitors (TKIs) may ideally work against both tumor and stromal cells. Here, we summarize the tumor-intrinsic and -extrinsic roles of c-Kit in cancer and discuss TKIs with their on- and off-targets, with a special emphasis on MCs as paradigmatic c-Kit-dependent accomplices for tumor progression
Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate
No full textIL-18, an immunoregulatory and proinflammatory cytokine, has been shown to play an important pathogenic role in Th1-driven autoimmune disorders. In this study, we evaluated the circulating levels and salivary-gland expression of IL-18 in patients with Sjögren's syndrome (SS), a mainly Th1-mediated disease. IL-18 serum levels were measured by ELISA in 37 patients with primary SS, 42 with rheumatoid arthritis, and 21 normal controls. We demonstrated high IL-18 serum levels in SS, similar to those in rheumatoid arthritis patients and significantly higher than in controls (P < 0.01). In addition, IL-18 serum concentrations were significantly higher in anti-SSA/Ro+ and anti-SSB/La+ than in anti-SSA/Ro- and anti-SSB/La- SS patients (respectively, P = 0.01, P < 0.01). Serum IL-18 correlated strongly with anti-SSA/Ro (P = 0.004) and anti-SSB/La (P = 0.01) titers. Salivary gland IL-18 expression was investigated by single/double immunohistochemistry in 13 patients with primary SS and in 10 with chronic sialoadenitis, used as controls. The expression of IL-18 was also examined in periductal inflammatory foci in relation to the acquisition of features of secondary lymphoid organs such as T–B compartmentalization, formation of follicular dendritic cell networks, and presence of germinal-center-like structures. IL-18 expression in SS salivary glands was detected in 28 of 32 periductal foci of mononuclear cells (87.5%), while no IL-18 production by infiltrating cells was detected in patients with chronic sialoadenitis. Within the inflammatory foci, IL-18 immunoreactivity co-localized almost exclusively with CD68+ macrophages. In addition, IL-18 was found in 15 of 19 foci (78.9%) with no evidence of T–B cell compartmentalization (nonsegregated) but in 100% of the segregated aggregates, both in T- and B-cell-rich areas. Strikingly, IL-18 was strongly expressed by CD68+ tingible body macrophages in germinal-centre-like structures both in SS salivary glands and in normal lymph nodes. IL-18 expression was observed in the ducts of all SS biopsies but in only 4 of 10 patients with nonspecific chronic sialoadenitis (P < 0.01). This study provides the first evidence of increased circulating levels and salivary gland expression of IL-18 in SS, suggesting an important contribution of this cytokine to the modulation of immune inflammatory pathways in this condition
Di Battista Pittoni pittore vicentino Imprese di diversi prencipi, dvchi, signori, e d'altri personaggi et hvomini letterati et illvstri : con alcune stanze del Dolce che dichiarano i motti di esse imprese.
No full textThe etched emblems appear within elaborate borders of strapwork, architectural elements, figures, masks, swags, fruit, etc. They include Latin mottos. Dolce's explanatory verses appear on the leaf following each emblem. These are printed letterpress, within one of two woodcut borders, and are numbered 1-52 at the upper right (mistakes, omissions). Plates [38] and [45] each contain two emblems.Place of publication taken from Venetian privilege on t.p. Date from that of dedication to Alfonso II, Duke of Ferrara (6 ottobre 1562).Landwehr, J. French, Italian, Spanish and Portuguese emblem books,Mode of access: Internet.At foot of many of Dolce's verses is a reference in brown ink to Paolo Giovio's Dialogo dell'imprese militari et amorose.Binding: later vellum. Author and brief title in gilt on red leather spine label. Page edges sprinkled red. Green silk place marker.Library's copy lacks dedicatory leaf ([2])
Experimental results on flow boiling and convective condensation of R134A in microfin tubes
No full textSaturated flow boiling and convective condensation experiments for oil-free Refrigerant-134a have been carried out with two microfin tubes with a new cross-section profile, as well as with a smooth one. All tubes have the same outer diameter of 9.52 mm; they are horizontally operated and are heated/cooled by a water stream. Both microfin tubes are characterized by sharp fins (apex angle of 40°) alternating with two different heights whereas the fin number is different, namely, 54 and 82. Evaporation tests are carried out at a nominal temperature of 5°C, for a mass flux ranging from about 90 to 340 kg/(m2s), inlet quality between 0.10 and 0.70, and quality change varying from 0.10 to 0.70, whereas for the condensation tests the nominal temperature is 35°C, the mass flux varies between 100 and 440 kg/(m2s), the inlet quality ranges from 0.75 to 0.10 and the quality change from 0.10 to 0.70. Finally, the paper presents comparisons between experimental data and estimates obtained by recent correlations specifically proposed for these tubes
Anestesia generale nella pratica odontostomatologica ambulatoriale Esperienza personale di 183 casi
No full textDecreased immunoreactive beta-endorphin in mononuclear leucocytes from patients with chronic fatigue syndrome
No full textOBJECTIVE: To investigate beta-endorphin concentrations in the peripheral blood mononuclear cells (PBMC) of patients with chronic fatigue syndrome (CFS). METHODS: Sixteen patients with CFS were enrolled in this study. Ten healthy subjects were studied as controls. Beta-endorphin concentrations were measured in PBMC by radioimmunoassay performed with antibodies specific for the C-terminal portion of human beta-endorphin. RESULTS: Beta-endorphin concentrations in the PBMC of chronic fatigue patients were significantly lower (p < 0.001) than in healthy subjects (mean +/- SD: 8.5 +/- 7.0 vs. 42.6 +/- 22.6). CONCLUSION: Patients with CFS were found to have low levels of PBMC beta-endorphin. This finding may reflect the condition of chronic immune activation in CFS that has been reported in previous investigations. Beta-endorphin concentrations in PBMC seem to mirror the central nervous system homeostasis of the opioid. Therefore, we would postulate that the fatigue and weakness typical of CFS could be related to low beta-endorphin concentrations at the central nervous system level
Thirty day post discharge BNP levels predict outcomes better than discharge levels - Italian RED study
No full textIntroduction: Heart failure (HF) patients often relapse into acute decompensation and consequent rehospitalization resulting in social and economic burdens. BNP has been previously shown to be prognostic at hospital discharge, but it has not been well characterized at time points after discharge from the emergency department (ED). Hypothesis: To determine the prognostic utility of BNP levels and changes in the emergency department (ED) and follow-up time-points. Methods: 276 HF patients were enrolled from 8 centers in Italy. The primary endpoints were cardiac associated rehospitalizations and deaths. Results: The Mean/Median BNP concentration at ED presentation was (mean±SE) 707.94±23.44pg/ml. Changes in BNP levels from presentation to 24h: –549.54±26.91pg/ml (p<0.001); to 72h: –426.57±26.91pg/ml (p<0.001); and at discharge: –323.59±29.51pg/ml (p<0.001). The mean/median BNP levels at follow-up time-points were 407.38±24.54 at 30 days, 363.07±29.51 at 60 days and 281.83±26.91pg/ml at 180 days. The BNP level at the 30 day follow-up was found to be highly predictive for events up to 180 days with an Area Under Curve (AUC) of 0.716 (p< 0.008) with a cut-point of 355pg/ml BNP and a hazard ratio of 8.56 (p = .014). The other considered BNP measurements did not significantly contribute to the prediction of the outcome. The discharge BNP level failed to significantly predict short term (within 30 days) outcomes (AUC: 0.647; p=0.054), and shows similar prognostic ability for long term (180 days) (AUC: 0.605; p<0.039).Conclusions: Tracking BNP levels post-discharge from the hospital may be equally important as the discharge BNP. Our results suggest that an increase in BNP at 30 days from the discharge BNP can be highly prognostic and may be a useful tool to discriminate between patients at higher risk for future events. This time period may be a crucial window to monitor BNP stability in the outpatient setting
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