2,683 research outputs found
Editorial IPRD06
No full textEditorial dei Proceedings del 10th Topical Seminar on Innovative Particle and Radiation Detectors (IPRD06) 1 - 5 October 2006 Siena, Ital
Editorial
No full textEditoriale dei Proceedings del 9th Topical Seminar on Innovative Particle and Radiation Detectors 23 - 26 May 2004 Siena, Ital
Overall and disease-free survival greater than 12 years in metastatic non-small cell lung cancer after linear accelerator-based stereotactic radiosurgery for solitary brain metastasis
No full textThe best treatment approach for solitary brain metastasis is not well defined and there is no consensus on this issue. It is still being debated whether patients with isolated brain metastasis should undergo surgical resection or stereotactic radiosurgery, and which patients should receive adjuvant whole brain radiotherapy. The median survival in patients with single or multiple metastatic lesions who underwent only stereotactic radiosurgery improved from two-three months to nine months. To the best of our knowledge this is the first report on patients treated with linear accelerator-based stereotactic radiosurgery alone where an overall survival of more than 12 years was obtained, maintaining good quality of life in three cases of solitary brain metastasis from non-small cell lung cancer. In addition to the case reports, we present a brief literature review on this topic. © Il Pensiero Scientifico Editore
Cerebral Proliferative Angiopathy (CPA) Imaging Findings and Response to Therapy
No full textWe report the case of a 55-year-old woman with cerebral proliferative angiopathy (CPA). Her medical history included brain surgery for small vascular lesions and suspicion of cerebral malignancy. C-11 methionine PET (C-11-METH PET) demonstrated a diffusely increased uptake on the right hemisphere. Contrast-enhanced MRI documented a massive lesion with a diffuse "nidus" appearance, involving the right cerebral hemisphere (sparing the inferior frontal gyrus and the anterior frontal lobe), the brainstem, and the middle cerebellar peduncle. Pathology confirmed the diagnosis of CPA and, after radiation treatment, the patient presented with clinical and radiological response
Innovative Particle and Radiation Detectors. Proceedings of the 10th Topical Seminar on Innovative Particle and Radiation Detectors
No full textCurrent status and recent advances in reirradiation of glioblastoma
No full textDespite aggressive management consisting of maximal safe surgical resection followed by external beam radiation therapy (60 Gy/30 fractions) with concomitant and adjuvant temozolomide, approximately 90% of WHO grade IV gliomas (glioblastomas, GBM) will recur locally within 2 years. For patients with recurrent GBM, no standard of care exists. Thanks to the continuous improvement in radiation science and technology, reirradiation has emerged as feasible approach for patients with brain tumors. Using stereotactic radiosurgery (SRS) or stereotactic radiotherapy (SRT), either hypofractionated or conventionally fractionated schedules, several studies have suggested survival benefits following reirradiation of patients with recurrent GBM; however, there are still questions to be answered about the efficacy and toxicity associated with a second course of radiation. We provide a clinical overview on current status and recent advances in reirradiation of GBM, addressing relevant clinical questions such as the appropriate patient selection and radiation technique, optimal dose fractionation, reirradiation tolerance of the brain and the risk of radiation necrosis
Stereotactic radiosurgery for patients with brain metastases
No full textWe read with interest the Article by Masaaki Yamamoto and colleagues1 about the use of stereotactic radiosurgery in patients with one to ten brain metastases. Their prospective, observational study was well designed and they enrolled many patients (n=1194); nevertheless, their findings raise several relevant questions about stereotactic radiosurgery and whole-brain radiotherapy. We have several concerns about the study. First, overall survival is not an appropriate primary endpoint to assess the effectiveness of a local therapy such as brain stereotactic radiosurgery
Proceedings of the 9th Topical Seminar on Innovative Particle and Radiation Detectors - Siena, Italy 23-26 May 2004
No full text11th Topical Seminar on Innovative Particle and Radiation Detectors (IPRD08) 1 - 4 October 2008 Siena, Italy
No full textThe Seminar is the eleventh in a series devoted since more than 20 years to experimental apparatus for high-energy particle physics and astrophysics. The previous ones were held in San Miniato (1984, 1986, 1988, 1990, 1993, 1996, 1998) and in Siena (2002, 2004, 2006). The 2008 Seminar will again focus on advanced technologies in particle physics at collider experiments, and in cosmic ray and astrophysics experiments, including balloon-borne and space based experiments. Special attention will be devoted to the application of these detectors in other fields, such as detectors for medicine and biology, security control, and environmental monitoring. The participation of representatives from industry will make it possible to discuss future applications of basic research. The Seminar will be based on review talks summarizing the progress of complex R&D projects and major facilities. Shorter talks will cover contributions on specific items. The presentation of posters is also foreseen.
MAIN TOPICS
* Tracking detectors
* Calorimeters
* Detectors for X and gamma ray astrophysics
* Cosmic ray experiments in space, on the earth's surface, and underground
* Neutrino experiments
* Radiation-hard detectors and electronics
* Detectors for medicine and biology
* Large X-ray systems for security control
* Simulations and new computing methods
* Detectors for environmental control
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