1,068 research outputs found
Signal sequence trap to clone cDNAs encoding secreted or membrane-associated plant proteins
No full textKristoffersen P, Teichmann T, Stracke R, Palme K. Signal sequence trap to clone cDNAs encoding secreted or membrane-associated plant proteins. Analytical Biochemistry. 1996;243(1):127-132
Supplemental material for Neurology residents’ knowledge of the management of headache
No full textSupplemental Material for Neurology residents’ knowledge of the management of headache by Espen Saxhaug Kristoffersen, Kashif Waqar Faiz and Bendik Slagsvold Winsvold in Cephalalgia</p
sj-docx-2-ict-10.1177_15347354231192959 – Supplemental material for A Qualitative Study Among Healthcare Providers on Risks Associated With the Use of Supportive Care for Cancer Treatment-Related Symptoms in Children and Adolescents
No full textSupplemental material, sj-docx-2-ict-10.1177_15347354231192959 for A Qualitative Study Among Healthcare Providers on Risks Associated With the Use of Supportive Care for Cancer Treatment-Related Symptoms in Children and Adolescents by Dana C. Mora, Agnete E. Kristoffersen, Miek C. Jong, Jill A. Hervik and Trine Stub in Integrative Cancer Therapies</p
sj-docx-1-ict-10.1177_15347354231192959 – Supplemental material for A Qualitative Study Among Healthcare Providers on Risks Associated With the Use of Supportive Care for Cancer Treatment-Related Symptoms in Children and Adolescents
No full textSupplemental material, sj-docx-1-ict-10.1177_15347354231192959 for A Qualitative Study Among Healthcare Providers on Risks Associated With the Use of Supportive Care for Cancer Treatment-Related Symptoms in Children and Adolescents by Dana C. Mora, Agnete E. Kristoffersen, Miek C. Jong, Jill A. Hervik and Trine Stub in Integrative Cancer Therapies</p
sj-xlsx-3-ict-10.1177_15347354231192959 – Supplemental material for A Qualitative Study Among Healthcare Providers on Risks Associated With the Use of Supportive Care for Cancer Treatment-Related Symptoms in Children and Adolescents
No full textSupplemental material, sj-xlsx-3-ict-10.1177_15347354231192959 for A Qualitative Study Among Healthcare Providers on Risks Associated With the Use of Supportive Care for Cancer Treatment-Related Symptoms in Children and Adolescents by Dana C. Mora, Agnete E. Kristoffersen, Miek C. Jong, Jill A. Hervik and Trine Stub in Integrative Cancer Therapies</p
ARR902402 Supplemental material - Supplemental material for Short tau inversion recovery MRI of Modic changes: a reliability study
No full textSupplemental material, ARR902402 Supplemental material for Short tau inversion recovery MRI of Modic changes: a reliability study by Per Martin Kristoffersen, Nils Vetti, Kjersti Storheim, Lars Christian Bråten, Mads Peder Rolfsen, Jörg Assmus and Ansgar Espeland in Acta Radiologica Open</p
sj-pdf-1-ict-10.1177_15347354221105563 – Supplemental material for Safety of Complementary and Alternative Medicine (CAM) treatment among children and young adults who suffer from adverse effects of conventional cancer treatment: A systematic review
No full textSupplemental material, sj-pdf-1-ict-10.1177_15347354221105563 for Safety of Complementary and Alternative Medicine (CAM) treatment among children and young adults who suffer from adverse effects of conventional cancer treatment: A systematic review by Dana C. Mora, Agnete E. Kristoffersen, Grete Overvåg, Miek C. Jong, Marit Mentink, Jianping Liu and Trine Stub in Integrative Cancer Therapies</p
Magnetic resonance imaging in breast diagnosis
No full textMRI of the breast has, since the introduction of gadolinium contrast agents, been increasingly used in breast investigations. MRI has been found to have a high sensitivity but a low specificity in cancer detection. The aim of this thesis was to study and establish the role of MRI in the clinical diagnosis of breast lesions. Which kind of lesions and which patients would benefit the most from MRI of the breast as an adjunct to other breast imaging modalities, and how should MRI be used in a clinical setting?In study I a comparison of the appearance of 27 lesions in two different T1-weighted 3D sequences regarding the contrast inherent in the sequences and following contrast enhancement was performed. Due to strong and widespread enhancement on the routine FLASH-sequence these lesions were examined with another T1-weighted sequence. The FLASH-sequence was found to have a high sensitivity, revealing contrast-enhancing areas, and therefore remains the first choice for routine examinations. The MPRAGE-sequence was found to increase the specificity by downgrading false positive lesions to true negatives.In study II the histological changes caused by fine needle aspiration biopsy (FNAB) that theoretically might affect the evaluation of breast lesions on semidynamic MRI was evaluated in 17 lesions. According to our result MRI can be performed irrespective of the time interval to a performed FNAB, as the evaluations were not impaired.In study III dynamic contrast enhanced MRI (CE-MRI) was found to be a valuable adjunctive method to clinical examination, mammography and FNAB (triple diagnosis,TD) due to high sensitivity, but at the cost of a decreased specificity. This decrease was less pronounced in mammographically dense breasts, and hence these patients might benefit most from CE-MRI as an adjunctive investigation.In study IV lesion size at CE-MRI and mammography were compared to histopathological size. The size of a breast cancer is of importance in the choice of treatment, in particular when breast-conserving surgery is considered. CE-MRI and mammography were both good at measuring the size of detected invasive breast malignancies. The total sizes of malignant lesions were frequently underestimated by both methods.In study V the diagnostic accuracy of CE-MRI and scinti-mammography was compared, and the clinical value as an adjunct to mammography was evaluated. Dynamic CE-MRI and 99mTc-sestamibi scinti-mammography showed comparable diagnostic accuracy, but a better accuracy was found for the combination of CE-MRI and mammography when using ROC curves for evaluation. In lesions smaller than 10 mm in size 99mTc-sestamibi scinti-mammography was found to be less reliable due to the low spatial resolution.In conclusion, MRI is a useful tool in breast diagnosis, in particular due to its high sensitivity, the ability to exclude multifocality/multicentricity and accuracy in determining size and extent of a lesion. Due to the low specificity MRI is not to be recommended as a general screening tool, but as an adjunctive method in selected cases.List of scientific papersI. Wiberg MK, Bone B, Bronge L, Aspelin P (1998). Comparison of the contrast enhancement pattern in two different T1-weighted 3-D sequences in MR imaging of the breast. Acta Radiol. 39(6): 680-5. https://pubmed.ncbi.nlm.nih.gov/9817041II. Kristoffersen Wiberg M, Bone B, Aspelin P (2000). The potential influence of fine-needle aspiration on MR imaging of the breast. Acta Radiol. 41(3): 222-6. https://pubmed.ncbi.nlm.nih.gov/10866075III. Kristoffersen Wiberg M, Aspelin P, Perbeck L, Bone B (2002). Value of MR imaging in clinical evaluation of breast lesions. Acta Radiol. 43(3): 275-81. https://pubmed.ncbi.nlm.nih.gov/12100324IV. KristoffersenWiberg M, Aspelin P, Sylvan M, Bone B (2002). Comparison of lesion size estimated by dynamic MR imaging, mammography and histopathology in breast neoplasms. European Radiology. [Accepted]V. Bone B, KristoffersenWiberg M, Szabo BK, Szakos A, Danielsson R (2002). Comparison of 99m Tc-sestamibi scintimammography and dynamic MR imaging as adjuncts to mammography in the diagnosis of breast cancer. Acta Radiologica. [Accepted]</p
sj-docx-1-msj-10.1177_13524585241231665 – Supplemental material for Autologous hematopoietic stem cell transplantation for multiple sclerosis: Long-term follow-up data from Norway
No full textSupplemental material, sj-docx-1-msj-10.1177_13524585241231665 for Autologous hematopoietic stem cell transplantation for multiple sclerosis: Long-term follow-up data from Norway by Christopher Elnan Kvistad, Anne Kristine Lehmann, Silje Agnethe Stokke Kvistad, Trygve Holmøy, Åslaug Rudjord Lorentzen, Linn Hereide Trovik, Einar Klæboe Kristoffersen, Lars Bø and Øivind Torkildsen in Multiple Sclerosis Journal</p
sj-docx-1-sjp-10.1177_14034948221108548 – Supplemental material for Milder disease trajectory among COVID-19 patients hospitalised with the SARS-CoV-2 Omicron variant compared with the Delta variant in Norway
No full textSupplemental material, sj-docx-1-sjp-10.1177_14034948221108548 for Milder disease trajectory among COVID-19 patients hospitalised with the SARS-CoV-2 Omicron variant compared with the Delta variant in Norway by Jeanette Stålcrantz, Anja Bråthen Kristoffersen, Håkon Bøås, Lamprini Veneti, Elina Seppälä, Nina Aasand, Olav Hungnes, Reidar Kvåle, Karoline Bragstad, Eirik Alnes Buanes and Robert Whittaker in Scandinavian Journal of Public Health</p
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