8,644 research outputs found
Table1_Bu-Fei-Huo-Xue capsule alleviates bleomycin-induced pulmonary fibrosis in mice through modulating gut microbiota.DOCX
Introduction: Bu-Fei-Huo-Xue capsule (BFHX) has been used to treat pulmonary fibrosis (PF) in clinic. However, the mechanism of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis remains unclear. Recent studies have shown that the changes in gut microbiota were closely related to the progression of pulmonary fibrosis. Modulating gut microbiota provides new thoughts in the treatment of pulmonary fibrosis.Methods: In this study,a mouse model of pulmonary fibrosis was induced using bleomycin (BLM) and treated with Bu-Fei-Huo-Xue capsule. We firstly evaluated the therapeutic effects of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis model mice. Besides,the anti-inflammatory and anti- oxidative effects of Bu-Fei-Huo-Xue capsule were evaluated. Furthermore, 16S rRNA sequencing was used to observe the changes in gut microbiota in pulmonary fibrosis model mice after Bu-Fei-Huo-Xue capsule treatment.Results: Our results showed that Bu-Fei-Huo-Xue capsule significantly reduced the collagen deposition in pulmonary fibrosis model mice. Bu-Fei-Huo-Xue capsule treatment also reduced the levels and mRNA expression of pro-inflammatory cytokines and inhibited the oxidative stress in lung. 16S rRNA sequencing showed that Bu-Fei-Huo-Xue capsule affected the diversity of gut microbiota and the relative abundances of gut microbiota such as Lactobacillus, Lachnospiraceae_NK4A136_group, and Romboutsia.Conclusion: Our study demonstrated the therapeutic effects of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis. The mechanisms of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis may be associated with regulating gut microbiota.</p
Tibetisoperla Huo & Du 2021, gen. nov.
<i>Tibetisoperla</i> Huo & Du, gen. nov. <p> <b>Diagnosis:</b> Small size, body length ca. 10 mm; macropterous, wing length 10–15 mm, general color dark brown or black. Triocellate, anterior ocellus smaller than posterior ones. Pronotum dark-colored medially with rugosities, with a smooth longitudinal band along the centerline. Wings hyaline. Terga 8–9 of male sclerotized posteriorly, bearing paired patches of sensilla; posterior half of tergum 10 bilobate, tip curved upwards with several large setae; vesicle on sternum 8 reduced; paraprocts developed and sclerotized, with a spiny apical sclerite. Aedeagus membranous, short columnar, without any sclerites, covered by fine spines.</p> <p> <b>Type species:</b> <i>Tibetisoperla wangluyui</i> Huo & Du, <b>sp. nov.</b> Monotypic.</p> <p> <b>Etymology:</b> This name combines “ Tibet ” and “ <i>Isoperla</i> ”, meaning “distributed in Tibet, similar to <i>Isoperla</i> ”.</p>Published as part of <i>Huo, Qing-Bo & Du, Yu-Zhou, 2021, A new genus of Isoperlinae (Plecoptera: Perlodidae) from Tibet, China, pp. 343-352 in Zootaxa 4996 (2)</i> on pages 343-344, DOI: 10.11646/zootaxa.4996.2.8, <a href="http://zenodo.org/record/5070043">http://zenodo.org/record/5070043</a>
Replication Package for: International Comovement in the Global Production Network
<p>This package contains the data and code necessary to reproduce the figures and tables in Huo, Levchenko and Pandalai-Nayar (forthcoming). "International Comovement in the Global Production Network," Review of Economic Studies. Detailed instructions are given about accessing the raw data, and running the code to generate output.</p>
Parisoperla oncocauda Huo & Du 2020, comb. nov.
Parisoperla oncocauda (Huo & Du, 2018), comb. nov. Isoperla oncocauda Huo & Du, 2018. Type locality: Tianmu Mountain, Zhejiang Province. Distribution: China (Zhejiang). Mature nymph: Body length c.a. 16 mm. Gills absent. Body covered with dark hair. Maculation of head and thorax typical of other Isoperlinae; M line and ecdysial line obvious. Mouthpart as shown in Fig. 3. Ventral tibial fringe absent. Wing pads subtriangular. Abdomen with a longitudinal pale band; paraprocts short; cerci long with setal fringe (Fig. 2). Material examined: 1 nymph, China, Zhejiang Province, Lin’an City, Tianmu Mountain Nature Reserve, Wuliting, 861m, 30°20.228′N, 119°26.136′E, 2018-IV-22, leg. Gao Peng. The same locality and data as holotype and paratypes of this species (ICYZU). Remarks: Only a single nymph available of the new genus from Tianmu Mountain was available for study. In the new genus, the Y-arms of the mesosternum and mandibles appear to be most similar to nymphs of Calliperla and Isoperla (Szczytko & Stewart 1984, Stewart & Stark 1993). The lacinia of P. oncocauda is similar to C. luctuosa (Banks, 1906) with the apex curved and inner margin straight (Szczytko & Stewart 1984), but the inner lacinial setal row of P. oncocauda is only present on the anterior apex angle, not reaching the base and sparser than C. luctuosa (about 8 thick setae and 20 fine hairs). No additional seta or setal patches occur on the surface of the lacinia.Published as part of Huo, Qing-Bo & Du, Yu-Zhou, 2020, A new genus and two new species of stoneflies (Plecoptera: Perlodidae) from Guizhou Province, China, pp. 470-480 in Zootaxa 4718 (4) on page 471, DOI: 10.11646/zootaxa.4718.4.2, http://zenodo.org/record/360263
Styloperla starki Zhao, Huo & Du 2019
<i>Styloperla starki</i> Zhao, Huo & Du, 2019 <p> <i>Styloperla starki</i>: Zhao <i>et al.</i>, 2019: 555.</p> <p> <b>Materials examined:</b> The specimens re-studied from Zhejiang and Jiangsu were recorded by Huo (2019), Zhao (2019), and Zhao <i>et al.</i> (2019).</p> <p> <b>Distribution:</b> Jiangsu and Zhejiang.</p> <p> <b>Remarks:</b> The number of ventral and subapical spines along the long process of the basal cercal segment varies between four and five (Figs. 7A–B); the apical spines are usually arranged side by side but may also be tandemed vertically (Figs. 7C–D); one apical and two of the subapical spines are occasionally aligned along the same plane (Fig. 8A–D).</p>Published as part of <i>Huo, Qing-Bo, Zhao, Meng-Yuan, Du, Yu-Zhou, Murányi, Dávid, Zhu, Bin-Qing & Yu, Lei, 2023, The intraspecific morphological variability of Styloperla Wu, 1935 (Plecoptera: Styloperlidae), pp. 125-137 in Zootaxa 5249 (1)</i> on page 129, DOI: 10.11646/zootaxa.5249.1.7, <a href="http://zenodo.org/record/7685409">http://zenodo.org/record/7685409</a>
Parisoperla leigongshana Huo & Du 2020, sp. nov.
Parisoperla leigongshana Huo & Du, sp. nov. Male: Forewing length ca. 11.2 mm, hindwing length 10.2 mm, body length 9.8 mm; general color brown (Fig. 11). Head brown, ocellar and frontoclypeal area dark brown. Antennae and palpi brown. Pronotum disc brown, rugosities present medially (Fig. 12A). Legs brown; wings hyaline, veins dark brown. Abdomen dark brownish and slightly sclerotized. Posterior margin of tergum 10 darkly sclerotized, recessed medially and rearward, extending as a process, with wide lateral grooves on surface, and perpendicular to tergum 10 posteriorly (Fig. 12B, Fig. 13). Vesicle reduced as a patch of bristles on posterior margin of sternum 8 (Fig. 12C). Paraprocts slender and lightly sclerotized. Female: Unknown. Egg: Unknown. Nymph: Unknown. Type material: Holotype: ♂, China, Guizhou Province, Leigongshan Nature Reserve, beside an unnamed road, 1198m, 26.3616N, 108.1650E, 2018-IV-22, leg. Du Yu-Zhou, Chen Zhi-Teng. Etymology: The scientific name refers to the type locality. Diagnosis: This species can be distinguished by the slender paraprocts and the shape of posteromedial margin of male tergum 10. Remarks: This species is similar to P. kuankuoshuiensis, except for the longer process on male terminalia and smaller paraprocts (Fig. 14). It is also similar to P. oncocauda, but the sclerotized areas on terminalia are different in shape. The posteromedial margin of tergum 10 of the male of P. leigongshana is narrowed in dorsal view. Parisoperla oncocauda bears a process which is wider at posteromedial tergal margin and tapers distally.Published as part of Huo, Qing-Bo & Du, Yu-Zhou, 2020, A new genus and two new species of stoneflies (Plecoptera: Perlodidae) from Guizhou Province, China, pp. 470-480 in Zootaxa 4718 (4) on pages 477-478, DOI: 10.11646/zootaxa.4718.4.2, http://zenodo.org/record/360263
Tibetisoperla Huo & Du 2021
Genus <i>Tibetisoperla</i> Huo & Du, 2021 <p> <i>Tibetisoperla</i> Huo & Du, 2021: 343.</p> Type species <p> <i>T. wangluyui</i> Huo & Du, 2021.</p> Diagnosis <p>Small sized. Macropterous. General color brown or black. Triocellate, anterior ocellus smaller. Tergum 10 with bilobate tip, covered with several large apical setae; paraprocts with spiny apical sclerite. Aedeagus membranous, covered by fine spines.</p>Published as part of <i>Yan, Yan-Hua, Chen, Zhen-Ning, Bozdoğan, Hakan & Li, Wei-Hai, 2022, The species of Tibetisoperla (Plecoptera: Perlodidae), pp. 125-140 in European Journal of Taxonomy 823</i> on page 126, DOI: 10.5852/ejt.2022.823.1821, <a href="http://zenodo.org/record/6658611">http://zenodo.org/record/6658611</a>
Parisoperla Huo & Du 2020, gen. nov.
Parisoperla Huo & Du, gen. nov. Diagnosis: Small size, body length 10~ 15 mm; macropterous, wing length 10~ 15 mm, general color dark brown; triocellus, area between posterior ocelli to compound eyes yellow brown. Pronotum width twice its length, darkcolored medially with rugosities, with a smooth longitudinal band present among the centerline. Terga 9–10 of male heavily sclerotized posteriorly, posteromedial margin of tergum 10 undivided, with a developed sclerotized process (Fig. 1 A–B) with wide lateral grooves on surface. Vesicle on sternum 8 reduced. Aedeagus membranous, short columnar, without any sclerites but covered ventrally by patches of fine spines. Female coloration similar to male, posterior margin of tergum 10 usually sclerotized and extending as a process like the male (Fig. 1 C–D). Subgenital plate rounded or short triangle, often with a median notch apically. Type species: Parisoperla oncocauda (Huo & Du, 2018). Etymology: This name indicates “ Para -” and “ Isoperla ”, means that “similar to Isoperla ”. Remarks: We previously treated P. oncocauda as a species of Isoperla Banks, 1906 based on the wing venation (Banks 1906) and aedeagal morphology (Sandberg & Kondratieff 2013, Szczytko & Kondratieff 2015). The wing venation and the paraprocts of Parisoperla are most similar to Isoperla, indicating a placement in the subfamily Isoperlinae. Within the Isoperlinae, several genera such as Calliperla Banks, 1948, Cascadoperla Szczytko & Stewart, 1979, Clioperla Needham & Claassen, 1925, Cosumnoperla Szczytko & Bottorff, 1987, Kaszabia Raušer, 1968 and Mesoperlina Klapálek, 1921 are also similar to the new genus. However, the male tergum 10 of Clioperla and Mesoperlina is cleft. The male of Kaszabia can be distinguished by a pair of tergal processes of the abdomen (although these processes are not a unique character of this subfamily, present also I. distincta Nelson, 1976 a Nearctic species of Isoperla) (Teslenko & Zhiltzova 2009, Judson & Nelson 2012, Szczytko & Kondratieff 2015); The monotypic Calliperla from western North America has the male tergum 10 short and broad, crescent-shaped, with a terminal process as well, but the process curving forward and upward, just as similar as Cosumnoperla. The aedeagus of Calliperla and Cosumnoperla are more complex in structure than the new genus (Bottorff 2007, Szczytko & Stewart 1984). Discussion: Geographically, the 15 known Chinese Isoperla species are mainly distributed in Palaearctic Region of China. Whereas Parisoperla is apparently restricted to Guizhou and Zhejiang provinces, which are considered the northern portion of the Oriental Region (Ma 1959, Zhang 2011). Therefore, we speculate that the genus may be an Oriental group of stoneflies.Published as part of Huo, Qing-Bo & Du, Yu-Zhou, 2020, A new genus and two new species of stoneflies (Plecoptera: Perlodidae) from Guizhou Province, China, pp. 470-480 in Zootaxa 4718 (4) on page 471, DOI: 10.11646/zootaxa.4718.4.2, http://zenodo.org/record/360263
Neowuia wuyishana Huo & Du 2023, sp. nov.
<i>Neowuia wuyishana</i> Huo & Du, sp. nov. <p>Figs. 1–5</p> <p> <b>Adult habitus.</b> General color dark brown (Fig. 1A). Head mostly pale brown except the frontocylpeus area and ocellar triangle with dark pattern (Fig. 1B–C). Triocellate, anterior ocellus smaller than posterior ones. Antennae and palpi dark brown. Pronotum disc rectangular (length:width ratio approximately 1:1.4), black laterally and dark brown medially; rugosities present laterally (Fig. 1B–C). Legs dark brown (Fig. 1A). Wings hyaline, veins dark brown, typical of this genus (Fig. 1D–E).</p> <p> <b>Male.</b> Forewing length 10.7 mm, hindwing length 9.1 mm, body length 10.0 mm. Abdomen brown (Figs. 2–3). Terga 1–6 with paired dark round dots laterally (Fig. 2A). Terga 8–9 bearing paired patches of sensilla on the posterior margin; terga 7–10 more sclerotized; tergum 8 with a large semicircular extension covered by long fine hairs at the median posterior margin; tergum 9 slightly sclerotized except the posterior margin (Figs. 2A, 3A). Tergum 10 with paired dense sensilla basiconica patches on anterior margin, without hemiterga but with a slim basal anchor medially; the anchor pointed in front and becomes larger “X” shaped extending in terminal (Figs. 3C–D plus inset). The vesicle of sternum 7 developed, large, and semicircular (Figs. 2B, 3B). Epiproct connected to tergum 10 only by membranous tissue; epiproct sclerite (Fig. 4A–B) consists of an oval closed ring with an upper, longitudinally bridge-jointed arm, and its tip ends of a strong beak-like extending. The paragenital plate is as triangular lobe, medially more sclerotized in dorsal view, inner lobes membranous and bearing large scales on the surface. Aedeagus membranous, without visible sclerite or spines.</p> <p> <b>Female.</b> Forewing length 10–11 mm, hindwing length 9.0– 9.5 mm, body length 10–11 mm. Body coloration similar to male (Fig. 1A, C). Subgenital plate broadly triangular (length:width ratio approximately 1:2.8), slightly sclerotized (Fig. 5A–B).</p> <p> <b>Egg.</b> 303.9 µm wide, 449.8 µm long. Turtle shaped, with one longitudinal dorsal ridge. Surface smooth and without visible micropyle or papillae. Collar 131.6 µm wide, present on the ventral position, with obscure papillae covered (Fig. 5C–D). Anchor semicircular, without massive stem, sparsely covered with several small globular bodies (Fig. 5D).</p> <p> <b>Nymph.</b> Unknown.</p> <p> <b>Type material:</b> Holotype: 1♁, China: Fujian Province, Wuyishan City, Mount Wuyi, Sangang, 2009-VI-1, leg. Xue Hai-Yang. Paratypes: 3♀♀, same locality and data as the holotype; 4 ♀♀, Wuyishan City, Mount Wuyi, from Tongmu Bridge to Yiliping (approximately 1 km from Sangang), 690m, 27.73512°N, 117.68541°E, 2021-V-14, leg. Huo Qing-Bo, Zhao Meng-Yuan, Zheng Wu.</p> <p> <b>Distribution.</b> China (Fujian).</p> <p> <b>Etymology.</b> The scientific name refers to Mount Wuyi (=Wuyishan), the type locality.</p> <p> <b>Diagnosis.</b> The new species can be distinguished from <i>N. qinlinga</i> by a combination of the large semicircular extension covered by hairs on tergum 8 (Fig. 2A), the large anchor with “X” shaped terminal on tergum 10 (Fig. 3C), the sclerite of epiproct consisting of a closed ring with longitudinally bridge-jointed arm and a beak-like extension, and the inner lobes of paragenital plate with large scales (Fig. 4).</p> <p> <b>Remarks.</b> This species lives on the vegetation adjacent to large rivers in Mount Wuyi (Fig. 6A). Adults exhibit phototaxis at night, since they were collected only on the light trap (Fig. 6B). The type locality of this species is more than 1100 km away (Fig. 6C) from the Qinling Mountains/ Sichuan Province, while they are mainly separated by Dabie Mountains and Wushan Mountains.</p>Published as part of <i>Huo, Qing-Bo & Du, Yu-Zhou, 2023, The second species of Neowuia Li & Murányi, 2017 (Plecoptera: Perlodidae) from Fujian, China, pp. 594-600 in Zootaxa 5339 (6)</i> on page 595, DOI: 10.11646/zootaxa.5339.6.8, <a href="http://zenodo.org/record/8313809">http://zenodo.org/record/8313809</a>
Isoperla oncocauda Huo & Du 2018, sp. nov.
<i>Isoperla oncocauda</i> Huo & Du, sp. nov. <p> <b>Male:</b> Forewing length ca. 11.0 mm, hindwing length 10.5 mm, body length 10.0 mm. Head mostly dark brown, anterior ocellus slightly smaller, posterior ocelli closer to compound eyes than to each other; area between posterior ocelli to compound eyes yellow brown (Figs. 1–2). Antennae and palpi dark brown. Pronotum disc wider than long, black, lateral margins yellowbrown, rugosities present medially (Figs. 1–2). Legs yellow brown; wings hyaline, veins dark brown (Figs. 3–4). Abdomen dark brown and slightly sclerotized. Posterior margin of tergum 10 darkly sclerotized, recessed medially and rearward, extending as a process, with wide lateral grooves on surface, and perpendicular to tergum 10 posteriorly. Paraprocts sclerotized, blunt apically (Figs. 5). Vesicle reduced, slightly projecting beyond anterior margin of sternum 9 (Fig. 6). Anteromedially, sternum 9 yellowish-brown, membranous; posterior margin truncate (Figs. 6–10). Aedeagus membranous without conspicuous sclerites (Figs. 11–12) [partially everted]. In lateral view with one large dorsal lobe bearing few rows of spinules, one anterolateral lobe and three posteroapical lobes. Ventral surface covered with dense scale-like spines increasing in size toward base. A triangular membranous notch near the middle of anterior margin; nail-shaped spines before the notch increasing in size posteriorly.</p> <p> <b>Female:</b> Forewing length 13.0 mm, hindwing length 11.5mm, body length 10.5 mm. Body coloration similar to male (Figs. 13–14). Abdomen brown, weakly sclerotized. Posterior margin of tergum 10 darkly sclerotized and extending as a process similar to male. Subgenital plate with basal sclerites laterally, broadly triangular, covering almost all of sternum 9, truncate apically with an obscure median notch (Figs. 15–18).</p> <p> <b>Egg:</b> Unknown.</p> <p> <b>Nymph:</b> Unknown.</p> <p> <b>Type material:</b> Holotype: ♂, China, Zhejiang Province, Lin’an City, Tianmu Mountain Nature Reserve, Wuliting, 861m, 30°20.228′N, 119°26.136′E, 2018-IV-22, leg. Huo Qing-Bo, Gao Peng. Paratypes: 1♂, 2♀♀, similar coloration with the holotype; the same locality and data as holotype.</p> <p> <b>Etymology:</b> The scientific name indicates the sclerotized developed process on the tergum 10 of the adult.</p> <p> <b>Discussion:</b> Of the 14 known Chinese <i>Isoperla</i> species, the new species is apparently most similar to <i>I. yangi</i> Wu, 1935 described from Jiangxi Province of southeastern China. Currently, the male of new species can be distinguished by the shape of the vesicle. In <i>I. yangi</i>, the vesicle is well-developed and ovoid in shape (Wu 1938), where as in <i>I. oncocauda</i> the vesicle is reduced and only slightly projecting beyond anterior margin of 9 th sternum. The female apparently can be distinguished from all known Chinese <i>Isoperla</i> females by the posterior margin of tergum 10 extending as a process. Of 14 Chinese species, the male aedeagi of only two northern Chinese species, <i>I. eximia</i> Zapekina-Dulkeit, 1975 and <i>I. lunigera</i> (Klapálek, 1923) have been illustrated in part (Teslenko & Zhiltzova 2009). In both of these species, the aedeagus possess distinctive aedeagal sclerites.</p> <p>The shallow stream of the type locality flows among the large rocks (Fig. 19). Adults were collected sitting on the rocks and from a nearby bridge.</p>Published as part of <i>Huo, Qing-Bo & Du, Yu-Zhou, 2018, A new species of the genus Isoperla (Plecoptera: Perlodidae) from TIANMU MOUNTAIN NATURE RESERVE, China, pp. 276-284 in Zootaxa 4504 (2)</i> on pages 277-282, DOI: 10.11646/zootaxa.4504.2.8, <a href="http://zenodo.org/record/2606285">http://zenodo.org/record/2606285</a>
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