594 research outputs found

    Syndrome specific modules to enhance the Stepping Stones Triple P public health intervention (Corrigendum)

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    Bezzina, L. A., Rice, L. J., Howlin, P., Tonge, B. J., and Einfeld, S. L. (2017) Syndrome specific modules to enhance the Stepping Stones Triple P public health intervention. Journal of Intellectual Disability Research, 61: 836–842. doi: 10.1111/jir.12405. In the article detailed above, the authors would like to advise readers that the MHYPEDD study group should appear in the author list and Acknowledgement section as below. L. A. Bezzina, L. J. Rice, P. Howlin, B. J. Tonge, S. L. Einfeld & MHYPEDD Study Group* *Authors' contributions: LB, LR, PH, BT, SE participated in manuscript preparation. All authors have read and approved the content of the manuscript. The Mental Health of Young People with Developmental Disabilities ‘MHYPEDD’ study group provided assistance in developing the study protocols and the syndrome specific modules. Acknowledgements: The ‘MHYPEDD’ study group comprises of Matt Sanders, Kate Sofronoff, Kylie Gray, Caroline Keating, Sian Horstead, Rebecca Wilson, and Kristina Clarke.No Full Tex

    Directive N° 96/82/ce Du Conseil Du 9 Décembre 1996 concernant la maîtrise des dangers liés aux accidents majeurs impliquant des substances dangereuses. (JOCE n°L 10, 14 janvier 1997, p. 13.)

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    Howlin B. Directive N° 96/82/ce Du Conseil Du 9 Décembre 1996 concernant la maîtrise des dangers liés aux accidents majeurs impliquant des substances dangereuses. (JOCE n°L 10, 14 janvier 1997, p. 13.) . In: Revue Européenne de Droit de l'Environnement, n°2, 1997. pp. 255-271

    Decontamination of prions, prion-associated amyloid and inefectivity from surgical stainless steel - implications for the risk of iatrogenic transmission of CJD

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    The physicochemical nature of the infectious agent in prion diseases creates asignificant challenge for decontamination services. It has been shown to be both resistant tostandard methods of decontamination, used to inactivate viruses and bacteria, and to associateavidly with surgical stainless steel. Moreover, the pathophysiology of the variant, iatrogenicand sporadic forms of Creutzfeldt-Jakob Disease (CJD) suggests deposition of the infectiousagent across a wide range of extraneural, lymphoid tissues, as well as in the skeletal muscleand blood. Coupled with the potential for asymptomatic carriers, there is a significant risk ofiatrogenic transmission of CJD through both neurosurgical procedures and standard surgery.This PhD study was undertaken in order to improve methods of instrumentdecontamination and to evaluate prion detection techniques and their applicability for theassessment of prion inactivation and removal. The project has provided relevant, criticalassessment of hospital decontamination procedures, in addition to guidance on how workingprotocols should be improved to provide a cleaner and safer end product for the patient.Moreover, laboratory studies have been performed to evaluate current methods of priondecontamination in the context of hospital procedures for instrument reprocessing. Challengesfaced by sterile service departments, such as soil drying and surface degradation, have beenaddressed and their impact on the risk of iatrogenic transmission of prions has beeninvestigated. Critically, the use of a fluorescent amyloid fluorophore for the detection of prionassociatedamyloid as a marker for disease permitted the investigation of the role of amyloidin infectious disease under denaturing conditions. Correlation of this detection technique withthe identification of PrPres by Western blot and infectious disease suggested that, whilstfluorescent detection of prion-associated amyloid was more sensitive than Western blot, PrPresdetection was more specific relative to infectivity. Improved fluorophores, with greatersensitivity, have been evaluated which will enhance in situ detection of prions in the future

    Does teaching a theory of mind have an effect on social communication in children with autism?

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    The present research examined whether teaching children with autism to pass tasks that assess mental state understanding had any positive effects on communication. Two aspects of communication previously shown to be deficient in children with autism were considered. These are conversational ability, in particular the ability to expand on conversation, and the use of mental state terms in speech. Results showed that no discernible improvement was seen on either measure of communication following mental state teaching. Discussion centers on real versus superficial changes in understanding mental states as a result of teaching

    Supplemental material for Audiovisual Aesthetics of Sound and Movement in Contemporary Dance

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    Supplemental Material for Audiovisual Aesthetics of Sound and Movement in Contemporary Dance by Claire Howlin, Staci Vicary and Guido Orgs in Empirical Studies of the Arts</p

    Interventions for Autism: Evidence for Educational and Clinical Practice (Book review)

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    Although there has been a number of recent reviews/meta-analyses on the effects of various treatment for autism these have generally focused on specific types of interventions (e.g. behavioural, social, sensory etc.). In this book, however, the author has attempted to bring together research on many different approaches to treatment and to assess the effectiveness of each of these.No Full Tex

    Adults with Autism: Changes in Understanding Since DSM-111

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    Over the past four decades there have been significant advances in our understanding of autism, yet services for autistic adults continue to lag far behind those for children, and prospects for employment and independent living remain poor. Adult outcomes also vary widely and while cognitive and language abilities are important prognostic indicators, the influence of social, emotional, familial and many other factors remains uncertain. For this special issue marking the 40th anniversary of DSM-III, the present paper describes the changing perspectives of autism in adulthood that have occurred over this period, explores individual and wider environmental factors related to outcome, and suggests ways in which services need to be changed to improve the future for adults living with autism.Full Tex
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