1,721,079 research outputs found
Vinblastine-treated primary cultures of rat liver: An experimental model for the detection of a specific enzyme-inducing action of phenobarbital on in vitro hepatocytes
No full textVinblastine-treated primary cultures of rat liver make up an experimental model to detect a specific enzyme-inducing action of phenobarbital on in vitro primary neonatal rat hepatocyte
La stimolazione dell’attività proliferativa degli epatociti di Ratto neonato in coltura primaria da parte dell’EGF e degli ormoni pancreatici è condizionata dalla concentrazione extracellulare di ioni calcio
No full textLa concentrazione extracellulare di calcio controlla l'entrata in DNA sintesi da parte degli epatociti stimolati da EGF, glucagone ed insulina
The growth-promoting effects of glucagon and insulin in primary neonatal rat hepatocytes are likely to be mediated via cyclic AMP and GMP
No full textThe growth-promoting effects of glucagon and insulin in primary neonatal rat hepatocytes are likely to be mediated via cyclic AMP and GM
The primary tissue culture of rat adult decapsulated adrenal glands: Problems of methodology and application.
No full textThe methodological problems related to the primary tissue culture of adult rat adrenocortical cells are thoroughly examined for the first time
L’ acido arachidonico e le prostaglandine A1, E1 ed E2 stimolano l’attività proliferativa degli epatociti di Ratto neonato in coltura.
No full textUn prodotto metabolico dell'acido arachidonico spettante alla via dell'endoperossido-sintetasi è capace di attivare mitoticamente gli epatociti quiescenti da un punto di vista proliferativo, in coltura in vitro
The primary tissue culture of rat adult decapsulated adrenal glands: Radioautographic studies on the metabolic effects of 322-1322-1322-1
No full textThis is a first report about the metabolic effects and proliferogenic actions of ACTH in normal rat adult decapsulated adrenal cortical cell
L’azione mitogena del glucagone e dell’insulina sugli epatociti di Ratto neonato in coltura primaria è mediata dai nucleotidi ciclici purinici.
No full textL'effetto mitogeno intraciclico esercitato dal glucagone e dall'insulina sugli epatociti di ratto neonato prevede l'intervento di meccanismi operativi coinvolgenti sia l'AMP che il GMP ciclici e, ovviamente, le chinasi proteiche specifiche la cui attività dipende da tali nucleotidi
Prostaglandins of the F series are extremely powerful growth factors for primary neonatal rat hepatocytes.
No full textAt low concentrations (i.e., 10(-12)-10(-9) mol/1), PGF1 alpha and PGF2 alpha very intensely stimulated both the DNA-synthetic and mitotic activities of hepatocytes in 4-day-old primary cultures of neonatal rat liver. DNA replication was more intensely enhanced by PGF2 alpha than by PGF1 alpha, whereas mitotic activity was nearly equally affected by the two prostaglandins. On the whole, the growth-promoting activity of PGF1 alpha used by itself or in equimolar mixtures with other prostaglandins (e.g., A1, E1, etc.) mimicked that of arachidonic acid we previously reported (1). On a molar basis, PGF2 alpha by itself stimulated hepatocytes' DNA synthesis more powerfully than arachidonate did, and when used in equimolar mixtures with other prostaglandins was at least as potent as arachidonic acid. These observations establish prostaglandins of the F series as quite powerful commitment factors and, though by a lesser degree, also intracycle regulators for neonatal rat hepatocytes in primary culture. However, the understanding of the role(s) of prostaglandins of F and other series in the physiological control of hepatocytes' proliferative activation must await the clarification of their interaction(s) with other arachidonate derivative(s) and polypeptide growth factor(s) which also may be involved in the process
Effetti dell’adenosinmono-fosfato 3’,5’- ciclico (cAMP) e guanosin-monofosfato 3’,5’-ciclico (cGMP) sulla sintesi di DNA in epatociti di Ratto in coltura primaria.
No full textEffetti dell’adenosinmono-fosfato 3’,5’- ciclico (cAMP) e guanosin-monofosfato 3’,5’-ciclico (cGMP) sulla sintesi di DNA in epatociti di Ratto in coltura primaria.ARCH.ITAL.ANAT
I nucleotidi ciclici purinici potrebbero regolare in modo positivo e sinergico la proliferazione epatocellulare nel Ratto neonato
No full textI nucleotidi ciclici purinici potrebbero regolare in modo positivo e sinergico la proliferazione epatocellulare nel Ratto neonat
- …
