1,721,008 research outputs found
Www.laureaonline.it: the Online Bachelor Programme in Computer Engineering at Politecnico di Milano, International Conference on Simulation and Multimedia in Engineering Education, San Antonio, Texas, 2002.
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Coagulation Disorders in Patients with Cancer: Nontunneled Central Venous Catheter Placement with US Guidance—A Single-Institution Retrospective Analysis
No full textPurpose: To assess the feasibility and safety of ultrasonographic (US) guidance in the placement of nontunneled central venous catheters (CVCs) in patients with cancer who had altered coagulation profiles. Materials and Methods: The study was approved by the institutional review board; informed consent was obtained. Medical charts of all patients with cancer who underwent nontunneled CVC placement at the European Institute of Oncology, Milan, from September 2001 to August 2008 were retrospectively reviewed. Patients were considered to have coagulation disorders or risk of bleeding when they had the following: prothrombin time more than 1.2 times normal or activated partial thromboplastin time more than 1.2 times normal and/or platelet count less than 150 × 10 9/L. Patients with a prothrombin time and partial thromboplastin time more than 2.2 times normal and/or a platelet count less than 50 000/mm 3 were considered to be at high risk for bleeding. Two hundred thirty-nine nontunneled CVCs were placed with US guidance in 157 patients. Results: One hundred twenty-two (51%) of 239 nontunneled CVCs were inserted in patients with cancer who had hemostasic disorders. Forty-five (37%) of 122 nontunneled CVCs were implanted in patients considered to be at high risk for bleeding. All catheters were successfully placed at the first needle pass with no major complications such as bleeding or pneumothorax. Two hundred thirty-three (97%) nontunneled CVCs were placed in the subclavian vein, and six (3%) were placed in the internal jugular vein. No patient underwent any correction for an abnormal coagulation profile. Conclusion: In patients with cancer who had coagulation disorders, nontunneled CVC placement with US guidance was feasible and safe and did not require correction of coagulation parameters
Contrast-enhanced ultrasonography in the follow-up of patients with hepatic metastases from breast carcinoma
No full textPurpose: To evaluate the use of contrast-enhanced ultrasound (CEUS) to obtain a precise measurement of hepatic metastases in breast cancer patients with fatty-liver.
Materials and methods: Twelve consecutive patients with 25 liver metastases from breast cancer and fatty liver defined by ultrasound criteria were enrolled in this prospective study. All patients underwent conventional ultrasound (US), contrast enhanced ultrasound (CEUS) and Multidetector Computed Tomography (MDCT), used as gold standard for measuring the maximum diameter of lesions. Agreement between measures performed by US and CEUS with reference MDCT was analysed by Altman-Bland plots method. The 95% agreement limits were calculated for the mean difference.
Results: Mean diameter measured by MDCT was 26.2 mm (range 11-83). US allowed to measure 20/25 lesions: 5 metastases were impossible to define. In 15 lesions the measure obtained by CEUS was more accurate than the one obtained by US. The mean difference to MDCT by CEUS is lower than by US and the differences between the means were 1.1 mm with 95% C.I. (-9.2, 11.4) for the measures by US and 0.6 mm with 95% C.I. (-2.0, 3.1) for the measures by CEUS.
Conclusion: Our preliminary data show that CEUS should be used to obtain more accurate parameters than conventional US for follow-up of patients with metastases in fatty-liver
Percutaneous placement of peritoneal port-catheter in oncologic patients
No full textThe aim of this paper is to describe the technique of percutaneous ultrasound (US)-guided placement of a peritoneal port-catheter in an interventional radiological setting. Nineteen patients with peritoneal carcinomatosis were selected for intraperitoneal port-catheter placement in order to perform intracavitary receptor-immuno- or radio-immunotherapy with Ytrium-90. All the procedures were performed percutaneously under US and fluoro guidance; the insertion site for catheters was chosen according to abdominal conditions and US findings: all devices were implanted at the lower abdominal quadrants. All patients were followed up with CT and US according to the therapy protocol. The procedure was successfully completed in 15/19 patients, in 4 being contraindicated by peritoneal adhesions. No procedure-related complications and device occlusions during therapy were observed; one catheter displaced 7 months later the placement. In our experience, this procedure was feasible, reliable and easy to perform, allowing the correct administration of the planned intracavitary therapy. Peritoneal adhesions are the main limitation of peritoneal port placement
SIMPLE: A program development system
No full textA program development system (PDS) should support a smooth transition between design, development, debugging, testing and final production of a software system. Man-machine interaction, though necessary, should not allow the user to modify the program or its execution state in an unstructured way; rather, disciplined interaction should be enforced by the PDS. After a review of the most desirable features of a PDS, the underlying philosophy of SIMPLE, a PDS which supports the development of Pascal programs, is introduced. The general structure of the SIMPLE system and the basic implementation choices are also discussed
Compiler testing using a sentence generator
No full textA system for assisting in the testing phase of compilers is described. The definition of the language to be compiled drives an automatic sentence generator. The language is described by an extended BNF grammar which can be augmented by actions to ensure contextual congruence, e.g. between definition and use of identifiers. For deep control of the structure of the produced sample the grammar can be described by step-wise refinements: the generator is iteratively applied to each level of refinement, producing at last compilable, complete programs. The implementation is described and some experimental results are reported concerning PLZ, MINIPL and some other languages
INTRAOPERATIVE ULTRASOUNDGUIDED LIVER RESECTION FOR INVISIBLE, NON-PALPABLE METASTATIC COLORECTAL CANCER: 144
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