1,731 research outputs found
La provincia delle Amazzoni : secondo la relazione del p. illuminato Giuseppe Coppi /
No full textIncludes Italian translations of excerpts from an article by Giuseppe Coppi."Estratto dal Bollettino della Società geografica italiana, marzo, 1885"--T.p. verso.Mode of access: Internet
Publisher correction: Human mid-trimester amniotic fluid (stem) cells lack expression of the pluripotency marker OCT4A
No full textIn the original version of this Article, the author Paolo De Coppi was incorrectly indexed. This error has now been corrected
Endogeneous magnetic reconnection and associated processes of relevance to fusion burning plasmas
No full textThe main characteristic of an endogenous magnetic reconnection process is that its driving
factor lays within the layer where a drastic change of magnetic field topology occurs. This
kind of process is shown to take place when a significant electron temperature gradient
is present in a magnetically confined plasma and when the evolving electron temperature
fluctuations are anisotropic r1s. Then r2s two classes of reconnecting modes are identified.
The localized class of mode involve a reconnected field B̃x of odd parity (as a function of
the radial variable), characteristic phase velocities and growth rates differently from the
commonly considered reconnecting modes associated with a finite effective resistivity. The
width of the reconnection layer remains significant even when large macroscopic distances
are considered. In view of the fact that there are plasmas in the Universe with considerable
electron thermal energy contents, the features of the considered modes can be relied upon
in order to produce generation or conversion of magnetic energy and high energy particle
populations through a sequence of mode-particle resonances r3s. With their excitation,
these modes acquire momentum in the direction of the main magnetic field component and
H
Tthe main body of the plasma column should recoil in the opposite direction r4s.
Endogenous modes associated with a finite electron temperature gradient are shown to be
sustained by the electron temperature heating rate due to the charged reaction products in
a fusion burning plasma r5s. In this case, the longitudinal thermal conductivity on selected
rational magnetic surfaces r5s is decreased, relative to its collisional value, by the effects of
reconnection.
The best agreement between theory and experiments concerning the onset of magnetic recon-
nection is (probably) represented by the theory of the resistive internal kink mode r6s. This
is reconsidered for regimes where the effects of local temperature gradients are important.
r1s B. Coppi and B. Basu, Phys. Lett. A, 382, 400 (2018).
r2s B. Coppi, Phys. Fluids, 8, 2273 (1965).
r3s B. Coppi et al., Nucl. Fus., 57, 7 (2017).
r4s B. Coppi, Nucl. Fus., 42, 1 (2002).
r5s B. Coppi et al., Nucl. Fus., 55, 053011 (2015).
r6s B. Coppi et al., Fiz. Plazmy, 2, 961 (1976)
Fausto Coppi, una icona dels temps moderns en l'Europa de postguerra
No full textRecensió de 'Coppi e il diavolo', 'El Giro de Italia', 'La pasión de Fausto Coppi', 'El Tour de Francia. Fausto Coppi hacia la gloria', i 'Arriva Italia. Gloria y miseria de la nación que soñó ciclismo'
Decellularized Tissue for Muscle Regeneration
No full textSeveral acquired or congenital pathological conditions can affect skeletal muscle leading to volumetric muscle loss (VML), i.e., an irreversible loss of muscle mass and function. Decellularized tissues are natural scaffolds derived from tissues or organs, in which the cellular and nuclear contents are eliminated, but the tridimensional (3D) structure and composition of the extracellular matrix (ECM) are preserved. Such scaffolds retain biological activity, are biocompatible and do not show immune rejection upon allogeneic or xenogeneic transplantation. An increase number of reports suggest that decellularized tissues/organs are promising candidates for clinical application in patients affected by VML. Here we explore the different strategies used to generate decellularized matrix and their therapeutic outcome when applied to treat VML conditions, both in patients and in animal models. The wide variety of VML models, source of tissue and methods of decellularization have led to discrepant results. Our review study evaluates the biological and clinical significance of reported studies, with the final aim to clarify the main aspects that should be taken into consideration for the future application of decellularized tissues in the treatment of VML conditions
Decellularized tissue for muscle regeneration
No full textSeveral acquired or congenital pathological conditions can affect skeletal muscle leading to volumetric muscle loss (VML), i.e., an irreversible loss of muscle mass and function. Decellularized tissues are natural scaffolds derived from tissues or organs, in which the cellular and nuclear contents are eliminated, but the tridimensional (3D) structure and composition of the extracellular matrix (ECM) are preserved. Such scaffolds retain biological activity, are biocompatible and do not show immune rejection upon allogeneic or xenogeneic transplantation. An increase number of reports suggest that decellularized tissues/organs are promising candidates for clinical application in patients affected by VML. Here we explore the different strategies used to generate decellularized matrix and their therapeutic outcome when applied to treat VML conditions, both in patients and in animal models. The wide variety of VML models, source of tissue and methods of decellularization have led to discrepant results. Our review study evaluates the biological and clinical significance of reported studies, with the final aim to clarify the main aspects that should be taken into consideration for the future application of decellularized tissues in the treatment of VML conditions
Stem cells from fetal membranes and amniotic fluid: Markers for cell isolation and therapy
No full textStem cell therapy is in constant need of new cell sources to conceive regenerative medicine approaches for diseases that are still without therapy. Scientists drew the attention toward amniotic membrane and amniotic fluid stem cells, since these sources possess many advantages: first of all as cells can be extracted from discarded foetal material it is inexpensive, secondly abundant stem cells can be obtained and finally, these stem cell sources are free from ethical considerations. Many studies have demonstrated the differentiation potential in vitro and in vivo toward mesenchymal and non-mesenchymal cell types; in addition the immune-modulatory properties make these cells a good candidate for allo- and xenotransplantation. This review offers an overview on markers characterisation and on the latest findings in pre-clinical or clinical setting of the stem cell populations isolated from these sources. © 2014 Springer Science+Business Media Dordrecht
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