676 research outputs found
Pediculus cameli Linnaeus, 1758, spec. nov.
No full textPediculus cameli [spec. nov.] P. Cameli. � Red. exp. t. 22. Habitat in Camelo Dromedario, Bactriano.Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 611, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/392220
Safe performance of echocardiography during the COVID-19 pandemic: A practical guide
No full textCoronavirus disease-2019 (COVID-19) outbreak has become a worldwide healthcare emergency, with continuously growing number of infected subjects. Considering the easy virus spread through respiratory droplets produced with cough, sneezes or spit or through close contact with infected people or surfaces, healthcare workers are further exposed to COVID-19. Particularly, echocardiography remains an essential diagnostic service which, due to the close contact with patients during the exam, provides echocardiographers high-risk of contagion. Therefore, the common modalities of performing echocardiography should be improved in this scenario, avoiding performing unnecessary exams, using the appropriate personal protective equipment depending on patients' status and location, optimizing time-effectiveness of the echocardiographic study and accurately sanitizing the environment and devices after each exam. This paper aims to provide a simple guide for the clinicians to balance between providing the best care to each patient and protecting themselves and other patients from the spread of the virus. It also proposes the use of the mnemonic PREVENT to resume the crucial indications to be followed for the execution of appropriate echocardiographic examination during the COVID-19 pandemic. © 2020 Cameli et al. Published by IMR press
Prevalence and pathologic study of Eimeria cameli in slaughtered camels
No full textAmaç: Araştırmanın amacı mezbahada kesime tabi tutulan develerde Eimeria enfeksiyonunun varlığını araştırmak ve gastrointestinal kanalda histopatalojik lezyonlarını tanımlamaktır. Gereç ve Yöntem: Kesilen 100 adet (68 erkek, 32 dişi, 6 ay - 8 yıl) deveye ait barsaklar Eimeria varlığı için mikroskopik olarak incelendi. Develer yaş (<2 yıl, 2-4 yıl, >4 yıl) ve cinsiyet (erkek, dişi) olarak 3 gruba ayrıldı. Eimeria spp. prevalansı ve gaitada ookist varlığı flotasyon ve sporulasyon teknikleri ile belirlendi. İntestinal kanaldan alınan doku örnekleri %10 formalinde sabitlendi. Örnekler parafine gömüldükten sonra 5 µm kalınlıkta kesilerek HematoxylinEosin ile boyandı. Bulgular: Araştırılan 100 devenin 29 (%29)’unda Eimeria cameli tespit. Develerde cinsiyet ve yaş grupları arasında hastalığın prevalansı açısından fark belirlenmedi (p>0.05). Mikroskopik incelemede eozinofilik enterit ve Lieberkuhn bezinin epiteli ile lamina propriada giant sizont, mikrogamet, makrogamet ve ookistler belirlendi. Öneri: Eimeria cameli enfeksiyonlarının İran’ın güney doğusunda yaygın olduğu ve kontrol programları düşünüldüğünde enfeksiyon varlığının değerlendirilmesinin faydalı olacağı ifade edilebilir.Aim: This study was carried out to determine Eimeria infection in slaughtered camel and describe the gross and histopathologic lesions caused by Eimeria species in the intestinal tract. Materials and Methods: Slaughtered 100 camels (68 males, 32 females, 6 months to 8 years, Kerman) were investigated for the presence of Eimeria parasites microscopically in intestinal tracts. Camels were classified into 3 groups according to the age (<2 years, 2-4 years, >4 years) and sex (male, female). The prevalence of Eimeria spp. infection and the intensity of faecal oocysts were determined using floatation and sporulation techniques. Tissue samples were taken from the intestinal tracts and then fixed in 10% buffered formalin. They were processed and embedded in paraffin. Sections of 5 µm thickness were cut and stained with Hematoxylin and Eosin. Results: Eimeria cameli were found in 29 (29%) of the 100 camels. Sex and age of camels did not have significant (p>0.05) effect on prevalence. Microscopic examination revealed eosinophilic enteritis and existence of developmental stages of the parasite such as giant schizonts, microgamont, macrogametocytes, and oocysts in the lacteals of lamina propria and in the epithelium of Lieberkuhn glands. Conclusion: Eimeria cameli infection is prevalent in camels in the south-eastern part of Iran and the evaluation of infection potential can be useful when considering control programs
Biopsy evidence of atrial myocarditis in an athlete developing transient sinoatrial disease.
No full textAtrial myocarditis causing transient sinoatrial disease (incessant atrial tachycardia alternating with sinoatrial pauses of up to 6 s in duration) in an athlete is reported. Diagnosis was undertaken by endomyocardial biopsy; biventricular and right atrial specimens were obtained. After a 6-month rest period, the atrial arrhythmias disappeared, and the athlete was able to resume his professional sporting activities
Exhaled nitric oxide is not increased in pulmonary sarcoidosis
No full textFractional exhaled nitric oxide (FeNO) is a non-invasive biomarker of airway inflammation and nitrosative stress. Previous studies have suggested a possible role of FeNO in the management of patients with pulmonary sarcoidosis, but published data are discordant
COVID-19 and the burning issue of drug interaction: Never forget the ECG
No full textThe coronavirus disease of 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), has been rapidly escalating, becoming a relevant threat to global health. Being a recent virus outbreak, there are still no available therapeutic regimens that have been approved in large randomised trials and so patients are currently being treated with multiple drugs. This raises concerns regarding drug interaction and their implication in arrhythmic burden. In fact, two of the actually used drugs against SARS-CoV2, such as chloroquine and the combination lopinavir/ritonavir, might determine a QT (the time from the start of the Q wave to the end of the T wave) interval prolongation and they show several interactions with antiarrhythmic drugs and antipsychotic medications, making them prone to an increased risk of developing arrhythmias. This brief review focuses the attention on the most relevant drug interactions involving the currently used COVID-19 medications and their possible association with cardiac rhythm disorders, taking into account also pre-existing condition and precipitating factors that might additionally increase this risk. Furthermore, based on the available evidence and based on the knowledge of drug interaction, we propose a quick and simple algorithm that might help both cardiologists and non-cardiologists in the management of the arrhythmic risk before and during the treatment with the specific drugs used against SARS-CoV2. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ
Serum amyloid A in patients with idiopathic pulmonary fibrosis
No full textBackground: Serum amyloid A (SAA) is an apo-lipoprotein (12–14 kDa) produced by the liver in response to proinflammatory cytokines from activated monocytes. The precursor of SAA is an acute-phase protein involved in the pathogenesis of sarcoidosis and has been found to be increased during exacerbation of chronic obstructive pulmonary disease and lung cancer. However, no data are available on SAA levels in patients with idiopathic pulmonary fibrosis (IPF), the most common and severe idiopathic form of interstitial pneumonitis associated with a usual interstitial histological and radiological pattern. The aim of this preliminary study was to evaluate SAA concentration in patients with IPF and to explore its potential use as a clinical biomarker. Methods: SAA levels were determined by enzyme-linked immunosorbent assay in a population of 21 patients with IPF (14 male, aged 64.8 ± 8.1 years) and compared with those in 11 healthy controls (3 male, aged 55 ± 11.3 years). Clinical, functional, and immunological data were collected in a database. Results: SAA levels were significantly higher in patients with IPF than in controls (p = 0.03). In patients with IPF, statistically significant correlations were found between SAA and HDL cholesterol levels (r = −0.62, p = 0.05) and FVC % predicted value (r = −0.52, p = 0.01). Conclusions: SAA is a promising marker of disease severity in patients with IPF. Our preliminary data suggest a potential pathogenetic role of alteration in lipid metabolism in this rare disease
Prognostic evaluation of alveolar concentration of nitric oxide, serum periostin and CD59 in patients with idiopathic pulmonary fibrosis
No full textPrevalence and pathologic study of eimeria cameli in slaughtered camels
No full textAim: This study was carried out to determine Eimeria infection
in slaughtered camel and describe the gross and histopathologic
lesions caused by Eimeria species in the intestinal
tract.
Materials and Methods: Slaughtered 100 camels (68
males, 32 females, 6 months to 8 years, Kerman) were investigated
for the presence of Eimeria parasites microscopically
in intestinal tracts. Camels were classified into 3
groups according to the age (4 years)
and sex (male, female). The prevalence of Eimeria spp. infection
and the intensity of faecal oocysts were determined
using floatation and sporulation techniques. Tissue samples
were taken from the intestinal tracts and then fixed in 10%
buffered formalin. They were processed and embedded in
paraffin. Sections of 5 μm thickness were cut and stained
with Hematoxylin and Eosin.
Results: Eimeria cameli were found in 29 (29%) of the
100 camels. Sex and age of camels did not have significant
(p>0.05) effect on prevalence. Microscopic examination
revealed eosinophilic enteritis and existence of developmental
stages of the parasite such as giant schizonts, microgamont,
macrogametocytes, and oocysts in the lacteals of
lamina propria and in the epithelium of Lieberkuhn glands.
Conclusion: Eimeria cameli infection is prevalent in camels
in the south-eastern part of Iran and the evaluation of
infection potential can be useful when considering control
programs
Exhaled nitric oxide in interstitial lung diseases
No full textNitric oxide (NO) is a biomarker of nitrosative stress, which is involved in the pathogenesis of idiopathic interstitial pneumonias (IIP). This study evaluates exhaled NO levels in IIP patients and relates alveolar concentrations of NO (CalvNO) to pulmonary function test (PFT) and 6-minute walking test (6MWT) parameters. We measured fractional exhaled nitric oxide (FeNO), CalvNO and maximum conducting airway wall flux (J'awNO) in 30 healthy subjects and 30 patients with IIP (22 idiopathic pulmonary fibrosis and 8 idiopathic non-specific interstitial pneumonias). IIP patients had higher FeNO at flow rates of 50-100-150 ml/s and higher CalvNO levels than healthy controls (p<0.0001). CalvNO was significantly correlated with 6-minute walking distance (p<0.0001), recovery time (p<0.0005), TLC (p<0.001), FVC (p=0.01) and TLCO (p<0.01). IIP patients showed abnormal nitric oxide production, probably due to lung fibrosis and oxidative-mediated lung injury. CalvNO was correlated with PFT and 6MWT parameters and is proposed as a potential biomarker of lung fibrosis and exercise tolerance
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