8,314 research outputs found
De Bonis Angelis Dei Filiis Commentatio : Programma S. Archangeli Michaelis Festo A. R. S. MDCCLXIV. In Academia Ivlia Carolina P. P. / [Christoph August Bode]
No full textHelmstedt, Univ., Programm, 1764Vermutl. Verf. ermittelt nach: WBIS, DBA, I 113,147. Lt. Einträgen in WBIS veröffentlichte Christoph August Bode 1760 "De Bonis Angelis Dei Filiis"Vorlageform des Erscheinungsvermerks: Helmstadii Typis Vid. P. D. Schnorrii Acad. Typogr
Carl Bode papers
No full textCarl Bode (1911-1993) was an author, professor of English at the University of Maryland, and officer of several literary and cultural organizations. His scholarly interests included Emerson, Thoreau, and H. L. Mencken. His books included Mencken, the first full biography to be published after Mencken's death; Maryland, a 350-year history of the state; The Man Behind You, a volume of poetry; and The Anatomy of American Popular Culture. He received a Ford Fellowship in 1952-1953 and a Guggenheim award in 1954-1955. Bode also founded the national American Studies Association. His papers consist of correspondence, drafts of publications, documentation from editing projects, and records of participation in political campaigns. Correspondence relates to Joseph Tydings, Walter R. Harding, and Wilson Follett. There is an unprocessed addendum to the collection, consisting of books on American literature and Maryland; correspondence; course materials; financial records; personnel-related materials; photographs; tapes; publications; and work papers
Reassessing the BODE score as a criterion for listing COPD patients for lung transplantation.
No full textBACKGROUND: The BODE score (incorporating body mass index, airflow obstruction, dyspnea and exercise capacity) is used for the timing of listing for lung transplantation (LTx) in COPD, based on survival data from the original BODE cohort. This has limitations, because the original BODE cohort differs from COPD patients who are candidates for LTx and the BODE does not include parameters that may influence survival. Our goal was to assess whether parameters such as age, smoking status and diffusion indices significantly influence survival in the absence of LTx, independently of the BODE.
METHODS: In the present cohort study, the BODE was prospectively assessed in COPD patients followed in a tertiary care hospital with an LTx program. The files of 469 consecutive patients were reviewed for parameters of interest (age, gender, smoking status and diffusing capacity of the lungs for carbon monoxide [DL,CO]) at the time of BODE assessment, as well as for survival status. Their influence on survival independent of the BODE score was assessed, as well as their ability to predict survival in patients aged less than 65 years.
RESULTS: A Cox regression model showed that the BODE score, age and DL,CO were independently related to survival (P-values <0.001), as opposed to smoking status. Survival was better in patients aged less than 65 in the first (P=0.004), third (P=0.002) and fourth BODE quartiles (P=0.008). The difference did not reach significance in the second quartile (P=0.13). Median survival for patients aged less than 65 in the fourth BODE quartile was 55 months. According to a receiver operating characteristic curve analysis, the BODE score as well as FEV1 and DL,CO fared similarly in predicting survival status at 5 years in patients aged less than 65 years.
CONCLUSION: Age and DL,CO add to the BODE score to predict survival in COPD. Assessing survival using tools tested in cohorts of patients younger than 65 years is warranted for improving the listing of patients for LTx
Bode Analysis of Uncertain Multivariable Systems
Get PDFBode plots are crucial for frequency domain analysis of SISO systems. The aim of this paper is to develop a complete approach for Bode plots of multivariable uncertain systems for both the magnitude and phase. The magnitude is based on the singular values. The phase is based on the phase spread of the numerical range. An IQC-based approach is pursued to provide both the magnitude and phase. A simulation example shows that the presented approach allows the generation of multivariable Bode plots of multivariable uncertain systems
Modified BODE indexes: Agreement between multidimensional prognostic systems based on oxygen uptake
No full textJos&eacute; Luis Lopez-Campos, Pilar Cejudo, Eduardo Marquez, Francisco Ortega, Esther Quintana, Carmen Carmona, Emilia BarrotUnidad M&eacute;dico-Quir&uacute;rgica de Enfermedades Respiratorias, Hospitales Universitarios Virgen del Roc&iacute;o, Seville, SpainAim: It has been recently shown that the original BODE index has a high degree of correlation with two modified BODE indexes using maximal oxygen uptake expressed either as mL/min/kg (mBODE) or as the percentage predicted (mBODE%). In this study we investigated the agreement between the two modified BODE indexes (mBODE and mBODE%) in patients with stable chronic obstructive pulmonary disease (COPD).Methods: A total of 169 patients with stable COPD were enrolled in this cross-sectional study. Differences between the two mBODE indexes were assessed using kappa coefficients and Bland-Altman plots. One out of every three patients underwent the six-minute walking test to investigate the agreement with the original BODE index.Results: Correlations between the two mBODE indexes with each other (r = 0.96, P &lt; 0.001) and with the original BODE index (mBODE r = 0.88, P &lt; 0.001; mBODE% r = 0.93, P &lt; 0.001) were excellent. However, the two mBODE indexes were significantly different from each other (mBODE 5.27 &plusmn; 2.3 versus mBODE% 4.31 &plusmn; 2.5; P &lt; 0.001). The kappa coefficients were significantly lower (entire study group k = 0.5, P &lt; 0.001) for every GOLD stage. The mean difference between the two mBODE indexes was 0.8 &plusmn; 0.6 units. Differences with the original BODE were higher for the mBODE (1.8 &plusmn; 0.9) than for the mBODE% (0.6 &plusmn; 0.8).Conclusions: The new mBODE indexes are highly correlated but significantly different from each other. The differences between the novel indexes deserve further scrutiny.Keywords: BODE index, chronic obstructive pulmonary disease, exercise testing, multidimensional evaluation, oxygen uptak
Evaluation of BODE index and its relationship with systemic inflammation mediated by proinflammatory biomarkers in patients with COPD
No full textNaushad Ahmad Khan,1,2 Mradul Kumar Daga,1 Istaq Ahmad,2 Govind Mawari,1 Suman Kumar,3 Naresh Kumar,1 Syed Akhter Husain2 1Department of Medicine, Maulana Azad Medical College, 2Department of Biosciences, Jamia Millia Islamia, 3Department of Microbiology, Maulana Azad Medical College, New Delhi, India Introduction: BODE index, a multidimensional grading system which is based on Body mass index, airway Obstruction, Dyspnea scale, and Exercise capacity, has been increasingly used for the evaluation of chronic obstructive pulmonary disease (COPD). Many of the systemic manifestations of COPD are shown to be mediated by elevated levels of proinflammatory biomarkers.Objective: We aimed to investigate the relationship between the BODE index, its components, disease severity, and proinflammatory biomarkers like C-reactive protein (CRP), tumor necrosis factor (TNF)-α, and interleukin (IL)-6.Materials and methods: A cross-sectional study which included 290 clinically stable COPD patients and 80 smoker controls was conducted. Medical history, body mass index, pulmonary function tests, 6-minute walking test, and modified scale of Medical Research Council dyspnea scale were evaluated. BODE scores were determined. Systemic inflammation was evaluated with the measurement of CRP, TNF-α, and IL-6 in the serum samples of all studied subjects. The correlation between inflammatory biomarkers and BODE index was assessed in COPD patients.Results: We found a significant relationship between COPD stages and BODE index. Our analysis showed significant association between systemic biomarkers and components of the BODE index. Both TNF-α and CRP levels exhibited weak but significant correlation with BODE index. Serum IL-6 concentrations exhibited significant correlation with 6-minute walking test, modified scale of Medical Research Council, and BODE index (r=0.201, P=0.004; r=0.068, P=0.001; and r=0.530, P=0.001, respectively). Also, an inverse and significant correlation was observed between BODE index and FEV1 (r=0.567, P=0.001). IL-6 exhibited a highly significant and inverse correlation with FEV1 (r=−0.580, P=0.001).Conclusion: BODE index should be considered for evaluating patients with COPD. Also, IL-6 seems to be a potential biomarker that may enable determination of the severity and prediction of the course of the disease. Keywords: BODE index, chronic obstructive pulmonary disease, systemic inflammation, biomarker
Denkschrift Auf Bode
No full textDENKSCHRIFT AUF BODE
Denkschrift Auf Bode ( - )
Frontispiece ( - )
P. M. ( - )
Titelseite ( - )
Zitat: Montaigne Th. VI. S. 174. nach Bode's Übersetzung. ( - )
Johann Joachim Christoph Bode ( - )
Erklärung. ( -
Interaktiivinen Bode-diagrammi suodatinsuunnittelun tueksi
Get PDFTiivistelmä. Bode–diagrammi kuvaa järjestelmän tulo- ja lähtösignaalin välistä vahvistusta ja vaihesiirtoa taajuuden funktiona. Suodatinsuunnittelussa diagrammia voidaan käyttää niin järjestelmän kuvaamisessa kuin sen vaatimusten määrittelyssäkin. Suodattimen siirtofunktio voidaan esittää graafisesti nollanapakartalla, josta taas voidaan määrittää suodatinsysteemin taajuusvaste. Kandidaatintyössä luotiin helppokäyttöinen web-ohjelmoitu Bode-diagrammin esitysmuoto, ottaen vastaan käyttäjän antama siirtofunktio interaktiivisen nollanapakartan avulla ja tuottamalla siitä systeemin taajuusvaste Bode -diagrammina
Adrenomedullin refines mortality prediction by the BODE index in COPD - The "BODE-A" index.
No full textpeer reviewedThe BODE index is well-validated for mortality prediction in COPD. Concentrations of plasma proadrenomedullin, a surrogate for mature adrenomedullin, independently predicted 2-year mortality among inpatients with COPD exacerbation.We compared accuracy of initial proadrenomedullin level, BODE, and BODE components, alone or combined, in predicting 1-year or 2-year all-cause mortality in a multicenter, multinational observational cohort with stable, moderate to very severe COPD.Proadrenomedullin was significantly associated (P<0.001) with 1-year mortality (4.7%) and 2-year mortality (7.8%), and comparably predictive to BODE regarding both (C statistics: 0.691 vs. 0.745, 0.635 vs. 0.679). Relative to using BODE alone, adding proadrenomedullin significantly improved 1-year and 2-year mortality prognostication (C statistics: 0.750, 0.818; both P<0.001). Proadrenomedullin plus BOD was more predictive than was the original BODE including 6-minute-walk distance. In multivariable analysis, proadrenomedullin (LR X2 13.0, P<0.001), body mass index (8.5, P=0.004), and 6-minute-walk distance (7.5, P=0.006), but not modified MMRC dyspnoea score (2.2, P=0.14) or FEV1 % predicted (0.3, P=0.60), independently foretold 2-year survival.Proadrenomedullin plus BODE better predicts mortality in COPD patients than does BODE alone; proadrenomedullin may substitute for 6-minute-walk distance in BODE when 6-minute-walk testing is unavailable
De Bonis Angelis Dei Filiis Commentatio. Programma S. Archangeli Michaelis Festo A. R. S. MDCCLXIV. In Academia Ivlia Carolina P. P / [Verf.: Christoph August Bode]
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