1,462 research outputs found

    Fortissat Science Alliance podcast: Layla Mathieson

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    Layla Mathieson was an EPSRC/MRC OPTIMA CDT PhD student studying optical medical imaging alongside an integrated Masters in healthcare innovation and entrepreneurship at the University of Edinburgh. She took part in the Fortissat Science Alliance podcast recordings in September 2021.What is the Fortissat Science Alliance?The Fortissat Science Alliance was a Wellcome Trust & Children In Need "Curiosity" project. This scheme provided informal STEM learning opportunities for young people who attended the community centre Getting Better Together Shotts (GBT Shotts) between 2019 and 2023. Due to the COVID-19 pandemic, deliveries had to pivot online so the podcast was founded. These recordings were made via Zoom with warm-up STEM activities sent to every young person in advance, along with a profile page for each researcher, so that they were relaxed and able to ask excellent questions.Link to episode on Spotify.Depending on the broadcast date, podcast deliveries were co-sponsored by Glasgow Science Festival, EXPLORATHON 2021, or EXPLORATHON 2022/23.For the duration of the project, it was supported jointly by Children in Need and the Wellcome Trust. In 2021, EXPLORATHON episodes were supported by the European Commission [grant agreement ID 101036101]. In 2022-23, EXPLORATHON episodes were supported by the Engineering & Physical Sciences Research Council [grant number EP/X020894/1]. Layla was supported by the EPSRC/MRC Centre for Doctoral Training in Optical Medical Imaging (OPTIMA).Author contributions to contentLayla Mathieson was the guest featured on this episode. Rebecca Hay was the youth worker coordinating the young people who conducted the interviews as well as co-editing and broadcasting the recordings. Iain Hamilton co-edited the episodes. Kirsty Ross was the STEM consultant for the project and uploaded completed episodes to Figshare.</p

    Portrait of John Powell, Joe Mathieson, Bill Obele and Rod Philip

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    1.3 x 0.9 negative, four young men in hats posing for photograph, two are standing and two are sitting6074A H96-21 Mathieson Family Photos Folder 6074A H96-21 Joseph R. Mathieson Photographs, ca. 1889-1991.32 Kodak PX 5062 L-R back row John Powell, Joe Mathieson front row Bill Obele, Rod Philip John Powell… son of Don Powell, Bad River rancher… still living 8/93 in Hot Springs, S. D. Joe Mathieson… son of Joseph R. & Sophie Rousseau Bill Obele… he died in a small plane crash north of Ft. Pierre, along with Joe Depner who took family ranch photos I sent you. Rod Philip… Son of Scotty P. … married Joe M. 's cousin Ruth Borden (daughter Mabel M. & Jack Borden

    International Capital Flows and the Frankel-Dooley-Mathieson Puzzle

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    Frankel et al (1986) pointed out that industrialized countries have larger saving rate coefficients than do developing countries in the framework of Feldstein-Horioka puzzle. This is referred to as the Frankel-Dooley-Mathieson puzzle in this paper. This paper extends past analyses by incorporating indices of a domestic institutional and policy environment. Applying the resulting model to Sub-Saharan African countries, saving rate coefficients larger than those previously imagined were obtained. These results are consistent with the reality of capital regulations and other factors resulting in low capital flows in developing countries.capital mobility

    Mathieson Ranch, Philip SD, Haakon County

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    3 x 5 photograph, large fenced-in area with a windmill and garden next to a log cabin house, a couple of chickens are next to the gateTowns Pierre #10, SD Historical Society - Parker - Presho P34 Tab P-Q Poster board PhilipPhilip, S.D. View of old Mathieson ranch showing the garden, shop, laundry house, corrals

    Inclusion in the Early Years/ Mathieson, Kay

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    xviii,218 p.; 23 cm

    Inclusion in the Early Years/ Mathieson, Kay

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    xviii,218 p.; 23 cm

    Richard "Dick" Mathieson Ranch House, Philip SD, Haakon County

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    3 x 5 photograph, dirt road leading to a log cabin house, a corral is to the left of the roadTowns Pierre #10, SD Historical Society - Parker - Presho P34 Tab P-Q Poster board PhilipPhilip, S.D. View of Dick Mathieson ranch house on Bad River 1903 showing a portion of the Corrals. (These pictures were taken by Emma Meyer who worked for Janousek studio in Yankton - later was Mrs. George Morgan of Ft. Pierre

    REGULATORY ROLE OF OX22HIGH T-CELLS IN MERCURY-INDUCED AUTOIMMUNITY IN THE BROWN NORWAY RAT

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    The monoclonal antibody OX22 defines a functional split within CD4+ T cells in the rat, with OX22high cells mainly producing interleukin 2 (IL-2) and interferon γ and responsible for delayed-type hypersensitivity responses, and OX22low cells mainly producing IL-4 and -5 and responsible for providing B cell help. There are reciprocal interactions between OX22high and OX22low cells, and it has been suggested that the OX22low subset has a role in the prevention of autoimmunity. We have used OX22 in vivo to define the role of these subsets in mercuric chloride-induced autoimmunity in the Brown Norway rat. In this model, there is polyclonal B cell activation and animals develop widespread tissue injury. Treatment of thymectomized animals with OX22 led to a profound reduction in the number of OX22high T cells in the peripheral blood. OX22-treated animals consistently developed more severe tissue injury than controls given an irrelevant antibody of the same isotype. Control animals pretreated with broad spectrum antimicrobial drugs showed milder tissue injury, but this protective effect of antimicrobials was lost in OX22-treated animals. Transfer of naive T cells to OX22-treated animals provided protection, but if T cells were depleted in vitro of OX22high cells before transfer, this effect was lost. These data provide evidence for a protective immunoregulatory role for OX22high T cells in mercuric chloride-induced autoimmunity.link_to_subscribed_fulltex

    Separating sets of strings by finding matching patterns is almost always hard

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    We study the complexity of the problem of searching for a set of patterns that separate two given sets of strings. This problem has applications in a wide variety of areas, most notably in data mining, computational biology, and in understanding the complexity of genetic algorithms. We show that the basic problem of finding a small set of patterns that match one set of strings but do not match any string in a second set is difficult (NP-complete, W[2]-hard when parameterized by the size of the pattern set, and APX-hard). We then perform a detailed parameterized analysis of the problem, separating tractable and intractable variants. In particular we show that parameterizing by the size of pattern set and the number of strings, and the size of the alphabet and the number of strings give FPT results, amongst others. © 2017 Elsevier B.V

    Improvements to the Ainley-Mathieson Method of Turbine Performance Prediction

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    In 1951 Ainley and Mathieson published a method of predicting the design and off-design performance of an axial turbine (British ARC, R &amp; M 2974). The flow and hence the losses were calculated at a single “reference diameter” for each blade row. This method has been widely used ever since. A critical review of the method has been made, based on detailed comparisons between the measured and predicted performance of a wide range of modern turbines. As a result, improvements have been made in the formulas for secondary loss and tip clearance loss prediction. The accuracy of the improved method has been assessed. Despite its relatively simple approach, it is believed that it will remain of great value in project work and preliminary design work.</jats:p
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