259 research outputs found
Demande de congé de M. Renaut, curé de Preux-aux-Bois, lors de la séance du 8 mai 1791
No full textDemande de congé de M. Renaut, curé de Preux-aux-Bois, lors de la séance du 8 mai 1791. In: Archives Parlementaires de 1787 à 1860 - Première série (1787-1799) Tome XXV - Du 13 avril 1791 au 11 mai 1791. Paris : Librairie Administrative P. Dupont, 1886. p. 666
Demande de congé de M. Renaut, curé de Preux-aux-Bois, lors de la séance du 8 mai 1791
No full textDemande de congé de M. Renaut, curé de Preux-aux-Bois, lors de la séance du 8 mai 1791. In: Archives Parlementaires de 1787 à 1860 - Première série (1787-1799) Tome XXV - Du 13 avril 1791 au 11 mai 1791. Paris : Librairie Administrative P. Dupont, 1886. p. 666
Questiones Ioannis buridani super decem libros ethicor¯u aristotelis ad nicomachum
No full textCopia digital : Universidad de Navarra, DADUNLa fecha de publicación y el editor literario constan en el colofón (v. de última h.)Marca tip. en portSign.: a-z\p6\s, a-l\p6\s, m\p8\sError de fol., de h. 39 pasa a 41 y de 51 pasa a 53Port. a dos tintasTexto a dos colLetra gó
The Kimberley assessment of depression of older Indigenous Australians: prevalence of depressive disorders, risk factors and validation of the KICA-dep scale
No full textThis study aimed to develop a culturally acceptable and valid scale to assess depressive symptoms in older Indigenous Australians, to determine the prevalence of depressive disorders in the older Kimberley community, and to investigate the sociodemographic, lifestyle and clinical factors associated with depression in this population.
Methods
Cross-sectional survey of adults aged 45 years or over from six remote Indigenous communities in the Kimberley and 30% of those living in Derby, Western Australia. The 11 linguistic and culturally sensitive items of the Kimberley Indigenous Cognitive Assessment of Depression (KICA-dep) scale were derived from the signs and symptoms required to establish the diagnosis of a depressive episode according to the DSM-IV-TR and ICD-10 criteria, and their frequency was rated on a 4-point scale ranging from ‘never’ to ‘all the time’ (range of scores: 0 to 33). The diagnosis of depressive disorder was established after a face-to-face assessment with a consultant psychiatrist. Other measures included sociodemographic and lifestyle factors, and clinical history.
Results
The study included 250 participants aged 46 to 89 years (mean±SD = 60.9±10.7), of whom 143 (57.2%) were women. The internal reliability of the KICA-dep was 0.88 and the cut-point 7/8 (non-case/case) was associated with 78% sensitivity and 82% specificity for the diagnosis of a depressive disorder. The point-prevalence of a depressive disorder in this population was 7.7%; 4.0% for men and 10.4% for women. Heart problems were associated with increased odds of depression (odds ratio = 3.3, 95% confidence interval = 1.2,8.8).
Conclusions
The KICA-dep has robust psychometric properties and can be used with confidence as a screening tool for depression among older Indigenous Australians. Depressive disorders are common in this population, possibly because of increased stressors and health morbidities
PET Reveals Inflammation around Calcified Taenia solium Granulomas with Perilesional Edema
No full textOBJECTIVE: Neurocysticercosis, an infection with the larval form of the tapeworm, Taeniasolium, is the cause of 29% of epilepsy in endemic regions. Epilepsy in this population is mostly associated with calcified granulomas; at the time of seizure recurrence 50% of those with calcifications demonstrate transient surrounding perilesional edema. Whether edema is consequence of the seizure, or a result of host inflammation directed against parasite antigens or other processes is unknown. To investigate whether perilesional edema is due to inflammation, we imaged a marker of neuroinflammation, translocater protein (TSPO), using positron emission tomography (PET) and the selective ligand (11)C-PBR28. METHODS: In nine patients with perilesional edema, degenerating cyst or both, PET findings were compared to the corresponding magnetic resonance images. Degenerating cysts were also studied because unlike perilesional edema, degenerating cysts are known to have inflammation. In three of the nine patients, changes in (11)C-PBR28 binding were also studied over time. (11)C-PBR28 binding was compared to the contralateral un-affected region. RESULTS: (11)C-PBR28 binding increased by a mean of 13% in perilesional edema or degenerating cysts (P = 0.0005, n = 13 in nine patients). Among these 13 lesions, perilesional edema (n=10) showed a slightly smaller increase of 10% compared to the contralateral side (P = 0.005) than the three degenerating cysts. In five lesions with perilesional edema in which repeated measurements of (11)C-PBR28 binding were done, increased binding lasted for 2-9 months. CONCLUSIONS: Increased TSPO in perilesional edema indicates an inflammatory etiology. The long duration of increased TSPO binding after resolution of the original perilesional edema and the pattern of periodic episodes is consistent with intermittent exacerbation from a continued baseline presence of low level inflammation. Novel anti-inflammatory measures may be useful in the prevention or treatment of seizures in this population
Probabilistic Inference for Fast Learning in Control
No full text22.10.13 KB. Ok to add author version to spiralWe provide a novel framework for very fast model-based reinforcement learning in continuous state and action spaces. The framework requires probabilistic models that explicitly characterize their levels of confidence. Within this framework, we use flexible, non-parametric models to describe the world based on previously collected experience. We demonstrate learning on the cart-pole problem in a setting where we provide very limited prior knowledge about the task. Learning progresses rapidly, and a good policy is found after only a hand-full of iterations
Historia Augusta Latin / von Goulart, Simon / 1 Historiae Augustae
No full textChronologia Augusta, seu, temporum supputatio ab imperio C. Julii Caesaris, usque ad Domitiani excessum : addita est consulum nomenclatura, nec non rerum memorabilium toto hoc annorum curriculo, tum in Oriente, tum in Occidente gestarum, ex probatis historiis, epitome. - Lugduni : apud Franciscum le Preux, 1592 [112 p.]ex Plutarcho, Dione, Tacito, Suetonio, collectus. Accesserunt Breviaria singulis libris praefixa ; Perpetuae ad marginem notae morales ac politicae ; Gnomologia historica ; Orationum, et rerum insignium indices ; Ad lectorem, de instituto et usu historiae augustae, praefatioSignatures : *8 a-z8 A-Z8 Aa8 Bb4 ; *8 Cc-Zz8 AA-PP8 ; A-G8La 1ère partie du tome 1 des "Historiae augustae" est décrite dans GLN-3666 et la 2e dans GLN-5948. La "Chronologia augusta" est décrite dans GLN-3531La 2e partie des "Historiae augustae" a sa propre page de titre (pagination continue) : Historiae Augustae tomi primi pars altera, continens septem Caesarum, nempe Neronis, Galbae, Othonis, Vitellii, Vespasiani, Titi, Domitiani vitas, ex Dione, Tacito, Plutarcho & Suetonio collectas: cum breviariis, notis, etc. - Lugduni, apud Franciscum le Preux, M. D. XCIIILa "Chronologia augusta" a aussi sa propre page de titre, mais datée de 159
Referral bias in ALS epidemiological studies
No full textBackgroundDespite concerns about the representativeness of patients from ALS tertiary centers as compared to the ALS general population, the extent of referral bias in clinical studies remains largely unknown. Using data from EURALS consortium we aimed to assess nature, extent and impact of referral bias.MethodsFour European ALS population-based registries located in Ireland, Piedmont, Puglia, Italy, and Limousin, France, covering 50 million person-years, participated. Demographic and clinic characteristics of ALS patients diagnosed in tertiary referral centers were contrasted with the whole ALS populations enrolled in registries in the same geographical areas.ResultsPatients referred to ALS centers were younger (with difference ranging from 1.1 years to 2.4 years), less likely to present a bulbar onset, with a higher proportion of familial antecedents and a longer survival (ranging from 11% to 15%) when compared to the entire ALS population in the same geographic area.ConclusionsA trend for referral bias is present in cohorts drawn from ALS referral centers. The magnitude of the possible referral bias in a particular tertiary center can be estimated through a comparison with ALS patients drawn from registry in the same geographic area. Studies based on clinical cohorts should be cautiously interpreted. The presence of a registry in the same area may improve the complete ascertainment in the referral center
Revisiting Geneva: Robert Kingdon and the coming of the French Wars of Religion
No full textThe late Robert Kingdon’s Geneva and the Coming of the Wars of Religion in France, 1555-1563 (1956) was not merely an engaging and challenging piece of scholarship, it came to dominate the study of Genevan Protestantism and the city’s relationship with other Reformed communities, particularly those in France. Based on the rich archival records in Geneva, Kingdon’s work would inspire many subsequent scholars to investigate the questions he first raised in the 1950s. This volume is testament to the breadth of material he first covered, and demonstrates the variety of fields in which he came to have influence, including printing history, the role of the nobility in the Reformation, the functioning of the Consistory and the lives of pastors. Born out of a conference celebrating the fiftieth anniversary of his original book, this volume now stands as a memorial to a life of exemplary scholarship.Foreword / Sara K. Barker -- Robert M. Kingdon (1927-2010): a scholarly life well lived / Andrew Pettegree -- Geneva in the centre? The challenge of local church orders / Philip Conner -- The elites and the politicisation of the French Reformation: the work of Robert M. Kingdon and the origins of the Hugenot party / Hugues Daussy -- Genevan print and the coming of the Wars of Religion / Andrew Pettegree -- Settling quarrels and nurturing repentance: the Consistory in Calvin's Geneva / Jeffrey R. Watt -- Developments in the history of Geneva since the 1960s / William G. NaphyPublisher PD
- …
