795 research outputs found
PD24 - Oral food challenges to peanut in the pediatric population at the Allergy Department of the University Hospital of Montpellier, France.
Product relationships management enabler for concurrent engineering and product lifecycle management
The current competitive industrial context requires more flexible, intelligent and compact product lifecycles, especially in the product development process where several lifecycle issues have to be considered, so as to deliver lifecycle oriented products. This paper describes the application of a novel product relationships management approach, in the context of product lifecycle management (PLM), enabling concurrent product design and assembly sequence planning. Previous work has provided a foundation through a theoretical framework, enhanced by the paradigm of product relational design and management. This statement therefore highlights the concurrent and proactive aspect of assembly oriented design vision. Central to this approach is the establishment and implementation of a complex and multiple viewpoints of product development addressing various stakeholders design and assembly planning points of view. By establishing such comprehensive relationships and identifying related relationships among several lifecycle phases, it is then possible to undertake the product design and assembly phases concurrently. Specifically, the proposed work and its application enable the management of product relationship information at the interface of product-process data management techniques. Based on the theory, models and techniques such as described in previous work, the implementation of a new hub application called PEGASUS is then described. Also based on web service technology, PEGASUS can be considered as a mediator application and/or an enabler for PLM that externalises product relationships and enables the control of information flow with internal regulation procedures. The feasibility of the approach is justified and the associated benefits are reported with a mechanical assembly as a case study
Recommendations for the standardization of clinical outcomes used in allergen immunotherapy trials for allergic rhinoconjunctivitis: an EAACI Position Paper.
Skin Testing for Suspected Iodinated Contrast Media Hypersensitivity
The management of iodinated contrast medium (ICM) hypersensitivity has been a matter of debate. Skin testing to identify a subgroup of ICM allergic patients has been proposed, in addition to complete avoidance, provocation testing, or premedication.sponsorship: C. Breynaert has received research support in the format of a C1 internal grant; and has received travel support for congresses. P. Demoly has received consultancy fees from Stallergenes Greer, ALK, Chiesi, Medarini, and ThermoFisher Scientific; has received research support from AstraZeneca and MEDA/Mylan; and has received lecture fees from ALK and Stallergenes Greer. A. M. Chiriac has received research support from COBIOPHAD (Horizon2020 Project). The rest of the authors declare that they have no relevant conflicts of interest. (Stallergenes Greer, ALK, Chiesi, Medarini, ThermoFisher Scientific, AstraZeneca, MEDA/Mylan, COBIOPHAD (Horizon2020 Project))status: Publishe
The impact of GINA suggested drugs for the treatment of asthma on Health-Related Quality of Life: a GA(2)LEN review.
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