4,843 research outputs found
Magnesium sulfate reduces odulation of Adhesion Molecules Expression And Nitric Oxide Synthesis Following Administration Of Magnesium Sulfate In An Experimental Model Of Spinal Cord Injury
No full textResveratrol, a natural red wine polyphenol, reduces ischemia-reperfusion-induced spinal cord injury.
No full textBACKGROUND: Severe neurologic injury still represents one of the most devastating complications after surgical repair of thoracoabdominal aneurysms. We therefore aimed to investigate the protective effect of resveratrol, a natural polyphenol antioxidant present in grapes and wine, in an experimental model of spinal cord ischemia-reperfusion injury.
METHODS: Sixteen rabbits were assigned either to group A (n = 8; receiving resveratrol, treated group) or group B (n = 8; control group, nontreated group) and underwent a 30-minutes period of spinal cord ischemia by clamping the abdominal aorta between the left renal artery and the aortic bifurcation. Fifteen minutes before clamping, rabbits received either intravenous resveratrol (100 microg/kg; group A) or normal saline (group B). Functional assessment with Tarlov score at 8, 16, and 24 hours postoperatively, histopathologic assessment of the spinal cord, measurements of malondialdehyde levels, and myeloperoxidase activity in the spinal cord were performed.
RESULTS: Neurologic impairment (Tavlov score for group A = 4.38 +/- 1.19 and for group B = 0.38 +/- 0.74, p < 0.001), malondialdehyde levels (47.71 +/- 7.81 nmol/g versus 86.56 +/- 11.39 nmol/g, p < 0.001), and myeloperoxidase activity (2.13 +/- 0.72 nm/min versus 3.75 +/- 0.78 nm/min, p = 0.002) were significantly lower in the resveratrol-treated animals. Additionally, pathologically assessed outcomes were better in the resveratrol-treated group. The total number of motor neurons in the gray matter was significantly lower in the nontreated group than in the resveratrol-treated group (14.26 +/- 2.94 versus 29.12 +/- 3.64, p = 0.003).
CONCLUSIONS: Prophylactic use of resveratrol reduced neurologic injury and provided clinical improvement by attenuating the inflammatory milieu in the rabbit spinal cord ischemia/reperfusion model
PENGARUH CONTENT PROGRAM ACARA REQUEST KAMUS OZZERS 90.8 FM OZ RADIO JAKARTA TERHADAP LOYALITAS PENDENGAR REMAJA OZ CLUB JAKARTA
No full textPENGARUH CONTENT PROGRAM ACARA REQUEST KAMUS OZZERS 90.8 FM OZ RADIO JAKARTA TERHADAP LOYALITAS PENDENGAR REMAJA OZ CLUB JAKARTA - pengaruh, acara request kamus ozzers, loyalitas, pendengar, Remaj
PENGARUH ATRIBUT PRODUK TERHADAP PEMBENTUKAN CITRA OZ RADIO JAKARTA
No full textPENGARUH ATRIBUT PRODUK TERHADAP PEMBENTUKAN CITRA OZ RADIO JAKARTA - Atribut Produk, Citra Merek (Brand Image
Interactively using Semantic Web knowledge: Creating scalable abstractions with FacetOntology
No full textThe amount of knowledge accessible on the Semantic Web is growing, and there is a need for a scalable solution to facilitate exploring that data. Currently approaches to exploring Semantic Web data either focus on exploring resources individually, following links during exploration, and making little use of collated data, or take the approach of collating and aligning multiple sources into one store for one purpose, and hand-crafting a specific browsing interface onto it. We present an approach that provides a scalable browsing interface, which can browse knowledge from the Semantic Web at will. Our approach creates abstractions of knowledge, collated into facets, which are described using FacetOntology. FacetOntology facilitates describing facets from RDF data, suitable for use in creating datasets for faceted browsing
Minimally Invasive Saphenous Vein Harvesting Preserves Endothelial Cell Function in Human Saphenous Vein Grafts
No full textAdhesion Molecule Expression And Nitric Oxide Production In An Experimental Lung Ischemia-reperfusion Model: Beneficial Effects Of Resveratrol
No full textResveratrol Reduces Ischemia-reperfusion Induced Spinal Cord Injury: An Experimental Model In Rabbits
No full textGrowth Morphologies and Mechanisms of Non-Equilibrium Solidified MC Carbide
No full textGrowth morphologies and mechanisms of the carbide of group IVB and VB elements (MC carbide), a typical faceted crystal, were studied with an estimated cooling rate from 102 to 105 K/s. Results showed that although the growth morphologies of the MC carbide vary remarkably with solidification cooling rate, the solid/liquid interface is always atomically smooth, and the growth mechanisms are always lateral growth. The growth mechanism transition from lateral to continuous growth mode, which was predicted by the classic crystal growth theory, was not observed for the TiC type MC carbide within the estimated cooling rate range of 102?105 K/s
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