1,329 research outputs found
El Tlacuache Núm. 402 (2010). 402 Año 10 (2010) febrero. El Tlacuache
No full textLa visita franciscana-dominica de las Bóvedas: Tlaquiltenango por Laura Ledesma Gallegos. -La propagación del árbol de linaloe en invernadero por Emiliano Soriano Vicente, Ignacio García Madrid. -Hollywood guayabo por Berenice Fregoso V
L'ultimo mito. Storie della storia del mondo. Greche e barbare di Laura Orvieto
No full textEdizione critica e analisi del testo della Storia di Ercole e di Filottete pubblicata da Laura Orvieto ne «La Settimana dei Ragazzi» (III, 7, 16 febbraio 1947, p. 3), a confronto con gli altri scritti per ragazzi di argomento mitologico dell’autrice.Critical edition and analysis of the Storia di Ercole e di Filottete, published by Laura Orvieto in «La Settimana dei Ragazzi» (III, 7, 16 febbraio 1947, p. 3), compared to the other writings for children on classical mythology by the same author
Effects of Moritella viscosa antigens on pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) cell line (SHK-1)
No full textMoritella viscosa is the causative agent of winter ulcer disease in salmonids reared in North-Atlantic countries. In this study the effects of selected M. viscosa antigens on cytotoxicity and pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) macrophage-like cell line (SHK-1) were examined. SHK-1 cells were stimulated with live and heat-killed bacterial cells, extracellular products (ECP) and an extracellular vibriolysin, termed MvP1. Following incubation, cytotoxicity and expression levels of interleukin-1β (IL-1β) and interleukin-8 (IL-8) were examined at different time points. Both live M. viscosa cells and ECP were cytotoxic, but neither heat-killed cells, nor the MvP1 peptidase caused cell death. Expression levels of both IL-1β and IL-8 increased significantly after stimulation with live cells, but heat-killed cells only caused increased IL-8 expression. ECP did not affect IL-1β expression, but did stimulate IL-8 expression. The isolated MvP1 peptidase stimulated both IL-1β and IL-8 expression at the highest concentration tested. This study reveals a difference in the induction of pro-inflammatory gene expression in salmon SHK-1 cells between live and heat-killed M. viscosa cells, and also that an unknown secreted factor is the main stimulant of IL-β and IL-8 expression.ID: S1050464809000990; M3: Article; Accession Number: S1050464809000990; Author: Bryndis Bjornsdottir (a, b); Author: Mark D. Fast (b, 1); Author: Sandra A. Sperker (b); Author: Laura L. Brown (b, 2); Author: Bjarnheidur K. Gudmundsdottir (a, ∗); Affiliation: Institute for Experimental Pathology, University of Iceland, Keldur v/Vesturlandsveg, 112 Reykjavík, Iceland; Affiliation: National Research Council Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, Nova Scotia B3H 2Z1, Canada; Keyword: Moritella viscosa; Keyword: Extracellular products; Keyword: MvP1 vibriolysin; Keyword: Atlantic salmon; Keyword: SHK-1; Keyword: Gene expression; Keyword: Immune response; Keyword: Pro-inflammatory cytokine; Keyword: Interleukin-1β (IL-1β); Keyword: Interleukin-8 (IL-8); Number of Pages: 6; Language: English;Source type: Electronic(1
Laura Joan Cooper
No full textLaura Joan Cooper was born in Pittsburgh, California. and graduated from Birmingham High School in Van Nuys, California. While attending High School she also attended classes at the University of Southern California, ultimately receiving her B.A.in 1967. After college, she and her husband moved to New Haven, Connecticut, where he attended graduate school at Yale. During this period, Cooper worked as a secretary, the director of a college dormitory, and finally as a legal assistant for a New Haven public interest law firm. When her husband accepted a teaching position at Indiana University, Cooper enrolled at the University’s law school. As a law student, Cooper served as a Junior Writer (1972/73) for the Indiana Law Journal and as Executive Editor for v.49, 1973/74. She also served as an Associate Instructor for the first year law school course on Civil Procedure (1972/73), as well as for an undergraduate honors course (Fall 1973). Laura J. Cooper received her J.D. degree from Indiana University in 1974.
Upon graduating from law school, Cooper clerked for John S. Hastings at the United States Court of Appeals for the Seventh Circuit. In 1975, she joined the faculty of the University of Minnesota Law School, where she has spent her entire teaching career. She teaches in the areas of Civil Procedure, Conflicts, Labor Law, and Alternative Dispute Resolution in the Workplace. She has published articles on welfare law, conflicts, labor law, and arbitration and is the co-author of three books on workplace dispute resolution. Cooper was the first woman to receive tenure at the University of Minnesota Law School.
Laura J. Cooper was inducted into the Indiana University School of Law Academy of Law Alumni Fellows in 2002. Since 2003, Cooper has held the title of J. Stewart and Mario Thomas McClendon Professor in Law and Alternative Dispute Resolution at the University of Minnesota Law School.https://www.repository.law.indiana.edu/notablealumni/1073/thumbnail.jp
Laura Joan Cooper
No full textLaura Joan Cooper was born in Pittsburgh, California. and graduated from Birmingham High School in Van Nuys, California. While attending High School she also attended classes at the University of Southern California, ultimately receiving her B.A.in 1967. After college, she and her husband moved to New Haven, Connecticut, where he attended graduate school at Yale. During this period, Cooper worked as a secretary, the director of a college dormitory, and finally as a legal assistant for a New Haven public interest law firm. When her husband accepted a teaching position at Indiana University, Cooper enrolled at the University’s law school. As a law student, Cooper served as a Junior Writer (1972/73) for the Indiana Law Journal and as Executive Editor for v.49, 1973/74. She also served as an Associate Instructor for the first year law school course on Civil Procedure (1972/73), as well as for an undergraduate honors course (Fall 1973). Laura J. Cooper received her J.D. degree from Indiana University in 1974.
Upon graduating from law school, Cooper clerked for John S. Hastings at the United States Court of Appeals for the Seventh Circuit. In 1975, she joined the faculty of the University of Minnesota Law School, where she has spent her entire teaching career. She teaches in the areas of Civil Procedure, Conflicts, Labor Law, and Alternative Dispute Resolution in the Workplace. She has published articles on welfare law, conflicts, labor law, and arbitration and is the co-author of three books on workplace dispute resolution. Cooper was the first woman to receive tenure at the University of Minnesota Law School.
Laura J. Cooper was inducted into the Indiana University School of Law Academy of Law Alumni Fellows in 2002. Since 2003, Cooper has held the title of J. Stewart and Mario Thomas McClendon Professor in Law and Alternative Dispute Resolution at the University of Minnesota Law School.https://www.repository.law.indiana.edu/notablealumni/1073/thumbnail.jp
Métricas de autor Laura Elizabeth Castro Jiménez
No full textInforme de las métricas de autor de la Dra. Laura Elizabeth Castro Jiménez de las publicaciones indexadas en Google Académico cuyo objetivo es entregar un insumo para el fortalecimiento de las capacidades y potencialidades de los autores de la Universidad Santo Tomás en el posicionamiento y visibilidad de sus publicacionesReport of the author metrics of Laura Elizabeth Castro Jiménez of the publications indexed in Google Scholar whose objective is to provide an input for the strengthening of the capacities and potentialities of the authors of the Santo Tomás University in the positioning and visibility of their publications.http://unidadinvestigacion.usta.edu.c
Laura Orvieto and the Classical Heritage in Italy before the Second World War
No full textStudio della narrativa per l'infanzia di Laura Orvieto di argomento mitologico: fonti classiche e contesto culturale.Laura Orvieto (1876-1953) is a Jewish-Italian author of several books for children: her masterpiece is Storie della storia del mondo. Greche e barbare, which was published in Florence in 1910 for the first time, was translated into many languages, and is still reprinted and read throughout the world. The subject of this book is the Trojan War: the Classical world appears very frequently in Laura’s writings. It was argued that her writings on Classical Antiquity were inspired by English literature for children (Nathaniel Hawthorne, Charles Kingsley, Andrew Lang): this paper reconsiders Laura’s references to the Classical culture found in her writings within the cultural background of her family (with a special attention to her husband Angiolo Orvieto’s education and interests) and of Florence at the beginning of the 20th century. Moreover, a close analysis of Laura’s published and unpublished writings reveals her effort of drawing from the ancient sources. On the other side, some handwritten notes in Laura’s manuscript of Storie della storia del mondo. Greche e barbare – published for the first time here – can be recognised as written by the classical philologist and papyrologist Girolamo Vitelli: the texts of two letters – published for the first time here, too – sent to Laura by Vitelli confirm that Vitelli read this book before publication upon Laura’s request. The Appendix includes the edition of an unpublished chapter of Storie della storia del mondo. Greche e barbare
Economics and Taxation of Publishing and Its Alternatives
No full textHlavním cílem bakalářské práce je porovnat modely vydávání publikací a jejich alternativ s důrazem na zdanění v tomto odvětví. Pojem publikace a jejich alternativy zahrnuje knihy, e-knihy, audioknihy a podcasty. Se změnami v rychlosti předávání informací a preferencí zákazníků je nutné se věnovat tomuto tématu a analyzovat výhody a nevýhody jednotlivých modelů. S ohledem na změny zdanění v tomto odvětví je vhodné se věnovat i daňovým aspektům. V této práci jsou vysvětleny principy jednotlivých modelů vydávání a s nimi spojené daňové zatížení z pohledu autora či tvůrce.The main objective of the bachelor's thesis is to compare the models of publishing publications and their alternatives with an emphasis on taxation in this sector. The phrase publications and their alternatives includes books, e-books, audiobooks and podcasts. With changes in the speed of information transmission and customer preferences, it is necessary to address this topic and analyze the advantages and disadvantages of individual models. With regard to changes in taxation in this sector, it is appropriate to also address tax aspects. The thesis explains the principles of individual publishing models and the associated tax burden from the perspective of the author or creator
Evaluation of antimicrobial effectiveness of octenidine derivatives
No full textUniverzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové Katedra biologických a lékařských věd Autor: Laura Šefránková Školitel: PharmDr. Miroslav Kovařík, Ph.D. Konzultant: Mgr. Michaela Hympánová, Ph.D. Diplomová práce Název: Hodnocení antimikrobního účinku derivátů oktenidinu Studijní obor: Farmacie Úvod: Oktenidin dihydrochlorid patří mezi tzv. "gemini" surfaktanty neboli bis-kvarterní ekvivalenty kvarterních amoniových solí (KAS). KAS jsou obecně hojně využívané dezinfekční látky vykazující relativně nízkou toxicitu a vysokou účinnost. Bis-kvarterní KAS se vyznačují ještě lepšími povrchově aktivními vlastnostmi a biologickou odbouratelností. Oktenidin dihydrochlorid je považován za velmi perspektivní antimikrobiální látku pro jeho vysokou účinnost i vůči multirezistentním variantám bakterií. Nicméně jeho omezená rozpustnost ve vodných rozpouštědlech komplikuje jeho aplikaci z důvodu nutnosti použití organických rozpouštědel, která následně snižují snášenlivost při aplikaci do ran nebo na sliznice. Cíl práce: Cílem této práce bylo otestovat antimikrobiální účinnost 11 nových derivátů oktenidinu dihydrochloridu, které byly připraveny za účelem zvýšení účinnosti a zlepšení rozpustnosti ve vodných roztocích. Metody: Mikrodiluční bujónová metoda byla použita v první fázi testování ke...Charles University in Prague, Faculty of Pharmacy in Hradec Kralove Department of Biological and Medical Sciences Author: Laura Šefránková Supervisor: PharmDr. Miroslav Kovařík, Ph.D. Consultant: Mgr. Michaela Hympánová, Ph.D. Title: Evaluation of antimicrobial effectiveness of octenidine derivatives Diploma thesis Study program: Pharmacy Introduction: Octenidine dihydrochloride belongs to the group of so-called "gemini" surfactants, or bis-quaternary equivalents of quaternary ammonium salts (QAS). QAS are generally widely used disinfectants exhibiting relatively low toxicity and high efficacy. Bis- quaternary QAS are characterised by even better surface activity and biodegradability. Octenidine dihydrochloride is considered as a very promising antimicrobial agent for its high antimicrobial activity even against multi-drug resistant bacteria. However, its limited solubility in aqueous solvents complicates its application due to the need of organic solvents in product composition, which afterwards reduce wounds or mucous membranes tolerability. Aim: The aim of this work was to test the antimicrobial efficacy of 11 new derivatives of octenidine dihydrochloride, which were prepared with emphasis to increase efficiency and improve solubility in aqueous solutions. Methods: The microdilution broth method...Department of Biological and Medical SciencesKatedra biologických a lékařských vědFaculty of Pharmacy in Hradec KrálovéFarmaceutická fakulta v Hradci Králov
Impact of European funding in Kosice region
No full textThe Slovak Republic is one of the countries whose large regional differences still persist today. The Slovak Republic applies a regional policy to eliminate regional differences. This policy aims to develop lagging regions through European Union funding. This diploma thesis is devoted to Košice region which belongs to one of the less developed regions amongst Slovakia. The main goal is to clarify the issue of drawing European funds and to evaluate the impacts of drawing these funds in the Košice region in the periods 2007-2013 and 2014-2020. For the evaluation, the author will use various indicators that represent the standard of living in the region. Another goal of this diploma thesis is to point out the shortcomings in drawing from the funds and to suggest a solution for their partial elimination.Slovenská republika patrí medzi krajiny, v ktorých aj v dnešnej dobe pretrvávajú veľké regionálne rozdiely. Na odstránenie regionálnych rozdielov Slovenská republika využíva regionálnu politiku. Cieľom tejto politiky je rozvíjať zaostalejšie regióny prostredníctvom čerpania finančných prostriedkov zo štrukturálnych fondov Európskej únie. Medzi menej rozvinuté regióny na Slovensku patrí aj Košický kraj, ktorému sa bude táto práca podrobnejšie venovať. Hlavným cieľom tejto diplomovej práce je priblížiť sa k problematike čerpania finančných prostriedkov z Európskych štrukturálnych a investičných fondov a vyhodnotiť dopady čerpaniac týchto fondov na Košický kraj v programovom období 2007-2013 a 2014-2020. Na vyhodnotenie autorka využije rôzne ukazovatele, ktoré reprezentujú životnú úroveň v kraji. Ďalším cieľom práce je poukázať na nedostatky pri čerpaní finančných prostriedkov z Európskych štrukturálnych a investičných fondov a prípadne navrhnúť možné riešenie na ich čiastočné eliminovanie.Slovenská republika patří mezi země, v nichž i v dnešní době přetrvávají velké regionální rozdíly. K odstranění regionálních rozdílů Slovenská republika využívá regionální politiku. Cílem této politiky je rozvíjet zaostalejší regiony prostřednictvím čerpání finančních prostředků ze strukturálních fondů Evropské unie. Mezi méně rozvinuté regiony na Slovensku patří i Košický kraj, kterému se bude tato práce podrobněji věnovat. Hlavním cílem této práce je přiblížit se k problematice čerpání prostředků z Evropských strukturálních a investičních fondů a vyhodnotit dopady čerpaniac těchto fondů na Košický kraj v programovém období 2007-2013 a 2014-2020. K vyhodnocení autorka využije různé ukazatele, které reprezentují životní úroveň v kraji. Dalším cílem práce je poukázat na nedostatky při čerpání prostředků z Evropských strukturálních a investičních fondů a případně navrhnout možné řešení na jejich částečné eliminování
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