1,354,450 research outputs found
Mantovani Orsetti, Domenico
No full textBiografia del giurista Domenico Mantovani Orsetti, professore di diritto amministrativo nella facoltà giuridica bolognese all'indomani dell'unità italiana
Pelecium igneus Orsetti & Lopes-Andrade, sp. nov.
No full textPelecium igneus Orsetti & Lopes-Andrade, sp. nov. Figs 1−12 Type locality. “ Estação de Pesquisa, Treinamento e Educação Ambiental Mata do Paraíso ” (officially abbreviated as “ EPTEA Mata do Paraíso ”) in Viçosa, state of Minas Gerais, Southeast Brazil (20°48'08.0"S 42°51'21.7"W). Etymology. The specific epithet is from the Latin “ igneus ”, which means “on fire”, in reference to the reddish reflexes on pronotum and head. Diagnosis. A medium sized species (13 mm) distinguishable among other congeners by the combination of the following features: Fore body dorsum is bright metallic and thence contrasts sharply with the black elytra (Fig. 1). Head with frontal impressions punctiform (Figs 1, 3), with a short and shallow excavation. Pronotum with median line shallow (Fig. 1), barely discernible, deeper posteriorly; basal impressions very shallow. Apical labial and maxillary palpomeres triangular (Fig. 4). Adults of P. i gn e us and P. helenae are quite similar in the shape of the body, frontal fovea of head, median line and basal impressions of pronotum. However, in P. igneus the lateral edges of pronotum are more arcuate near base, giving it a subcordate shape when seen from above. Moreover, in P. igneus the elytra is comparatively rounder when seen from above and is shiny black, contrasting with its metallic reddish pronotum. In P. helenae, the dorsum is homogeneously violaceus. Description, male holotype (Figs 1–12). Fully pigmented adult. Measurements in mm: AL1-11: 0.81, 0.48, 0.55, 0.52, 0.56, 0.50, 0.44, 0.45, 0.43, 0.45, 0.65, EL 6.89, EW 5.18, lp2L 0.57, lp3L 0.83, lp3 W 0.51, mp3L 0.24, mp4L 0.68, mp4 W 0.46, PL 3.85, PW 3.83, SL 0.49, SW 0.67, TL 12.85. Ratio: TL/EW 2.48. Body ovate and flat; discs of head and pronotum metallic wine reddish in dorsal view, with greenish and yellowish reflections along sides (Fig. 1); elytra shiny black (Fig. 1), glabrous, with only standard setae present (supraorbital, pronotal and parascutellar setae); ventral surface shiny black (Fig. 2), Head microreticulate, with a pair of frontal punctiform fovea, each with a short and shallow excavation at the outer side (Fig. 3, arrows). Mouth parts (Fig. 4): apical labial and maxillary palpomeres triangular, with long and sparse yellowish setae, surface mostly reddish brown, with apicalmost portion yellowish; fourth maxillary palpomere subtriangular, 2.8X as long as the third palpomere, covered with sparse yellowish slender setae, surface reddish brown, with apicalmost portion yellowish. Pronotum (Fig. 1) subcordate, minutely rough (in low magnification) to transversely microstriate (in magnification above 100X); lateral margins rounded in apical 4/5, sinuate just in front of basal angles; base truncate, with sides strongly oblique towards highly obtuse and blunt basal angles; median line fine and shallow, deeper posteriorly; basal impressions inconspicuous. Scutellum triangular (Fig. 1), minutely rough (in low magnification) to microreticulate (in magnification above 100X). Elytra with inner five interneurs deep; in between interneurs shiny and unpunctate, minutely rough (in low magnification) to transversely microstriate (in magnification above 100X). Protibiae (Fig. 2) expanded at apex. Mesotibiae (Fig. 2) not expanded at apex; densely pubescent ventrally, more ventroapically. Metatibiae (Fig. 2) slender, densely pubescent in apical half of ventral side. Abdominal tergite IX (Fig. 12) oval, asymmetric, with anterior portion narrowed to a sharp apex; posterior portion with asymmetric expansions on each side; posterior edge barely curved and growing to an obtuse angle. Aedeagus (Figs 5−11) with penis (Figs 5−9) cylindrical, slender, conspicuously curved in lateral views (Figs 6, 8, 9), its apical edge straight (Figs 5, 7); parameres asymmetric (Figs 7, 10−11), left paramere (Fig. 10) longer and narrower than right paramere (Fig. 11). Type series. Holotype ♂ (CELC), labeled “ BRASIL: MG, Viçosa Mata do Paraíso, 08.xii.2014 pitfall, trilha do pesquisador leg. A. Orsetti \ Pelecium igneus Orsetti & Lopes-Andrade HOLOTYPUS [printed in red paper]”. Comments. The sexsetose labrum, combined with quadrisetose pronotum, defines Pelecium igneus as a member of the subgenus Pelecium (s. str). Pelecium igneus is the unique species in the genus in which the color of head and pronotum is different from the color of elytra. We include P. i g ne u s in P. rotundipenne species group based on the following features: head frontal fovea punctiform, pronotum basal impression moderately deep to shallow, elytral interneurs 6 and 7 absent, interneurs 5 absent or reduced (Straneo & Ball 1989). It is necessary to alter part of the definition of the P. rotundipenne group, which now includes species with black colored, coppery, violaceus and partially reddish dorsum. Pelecium igneus sp. nov. can be identified using key in Straneo & Ball (1989), with couplets 25 and 26 modified in the following way: 25(24’) Elytron with only discal interneurs 1–4 deep, and only interneur 1 extended to apical declivity, 4 remote from base and apex. Pronotum with posterolatera1 impressions indistinct, shallow.............................................................................. P. purpureum 25'. Elytron with at least interneurs 1–5 moderately deeply impressed, and extended to rather gradually sloped apical declivity. Pronotum with posterolateral impressions various................................................................................................................ 25a 25a(25’) Pronotum with sides markedly rounded; posterolateral impressions evident.............................................................. P. paulae 25a’ Pronotum with sides less rounded, subsinuate to sinuate posteriorly; posterolateral impressions indistinct.......................... 26 26(25a’) Pronotum reddish, with green reflections laterally. Elytra black, with violaceous reflections.......................... P. igneus sp. n. 26’ Dorsum unicolored dark purplish, without green reflections laterally....................................................................... P. helenaePublished as part of Orsetti, Artur & Lopes-Andrade, Cristiano, 2016, A new species of Pelecium Kirby (Coleoptera: Carabidae: Peleciini) from the Atlantic Forest biome, Brazil, pp. 123-127 in Zootaxa 4179 (1) on page 124, DOI: 10.11646/zootaxa.4179.1.9, http://zenodo.org/record/26170
Cis regius Orsetti & Lopes-Andrade, sp. nov.
No full textCis regius Orsetti & Lopes-Andrade, sp. nov. Figs 1–10 Type locality. “Prince Alfred’s Pass” (route 339), coordinates 33º58’S, 23º09’E (Diepwalle Forest, north of Knysna). Etymology. The specific epithet is from the Latin “ regius ”, which means “regal”, in reference to the head of males bearing four subtriangular plates that somewhat resembles a crown. Diagnosis. Pronotum in both genders with anterior portion bearing setae much longer than in the remaining pronotal surface (female, Fig. 4; more conspicuous in male, Fig. 1, arrow). Elytra with vestiture of seriate bristles. In males, the anterior edge of head is projected into four short subtriangular plates with rounded apices (Fig. 5, small arrows); and the anterior portion of occiput bears a small but conspicuous tubercle at middle (Fig. 5, big arrow). In male genitalia, the tegmen has a subtriangular apical portion delimited by lateral excavations (Fig. 8, arrows); the penis is narrow and elongate (Fig. 9). In females, the ovipositor bears an inner protuberance in each apical gonocoxite, at the side of each gonostylus (Fig. 10, arrows). Description, male holotype (Figs 1–3, 5, 6) Fully pigmented adult lacking the following structures: club and funicle of left antenna, left protibia and mesotibia, right metatibia, and most tarsomeres. Measurements in mm: TL 1.56, PL 0.63, PW 0.76, EL 0.94, EW 0.77, GD 0.67. Ratios: PL/PW 0.82, EL/EW 1.22, EL/PL 1.51, GD/EW 0.86, TL/EW 2.03. Body elongate, convex, evenly reddish brown; dorsal vestiture of pale yellowish bristles easily discernible in low magnifications (<50X); ventral vestiture of pale yellowish slender decumbent setae, most abundant on abdomen. Head with dorsal surface microreticulate, but unpunctated, and bearing four short subtriangular plates with rounded apices (Fig. 5, small arrows), which let the anterior portion of head somewhat resembling a crown; vertex concave; occiput with a conspicuous tubercle projected forward, placed at the middle of the anterior portion (Fig. 5, big arrow). Antennae bearing ten antennomeres, as follows (in mm, right antenna measured): 0.06, 0.06, 0.04, 0.03, 0.02, 0.02, 0.02, 0.04, 0.06, 0.07 (FL 0.13, CL 0.17, CL/FL 1.31). Eyes coarsely facetted, with about 75 ommatidia; GW 0.13 mm. Pronotum with dual punctation, the coarse punctures separated from each other by one to two puncture-widths; surface between punctures conspicuously microreticulate; small punctures devoid of setae and large punctures bearing short setae (~ 0.03 mm); anterior portion with scattered long slender setae (0.07–0.09 mm; Fig. 1, arrow), this area is slightly downgraded, which is better seen in lateral view (Fig. 2); lateral to anterior edges broadly rounded and bearing a row of slender setae; lateral edges weakly crenulate, narrowly explanate, not visible when seen from above. Scutellum subtrapezoidal, glabrous and almost unpunctate; BW 0.08. Elytra with single and confuse punctation, denser and more uniform than that of pronotum; surface in between punctures somewhat rugose, shiner than pronotum; vestiture of seriate setae (0.04–0.05 mm). Hind wings developed, apparently functional. Hypomera with very fine and sparse punctation; each puncture bearing a very slender seta; surface a bit irregular, but not microreticulate. Prosternum in front of coxae biconcave; surface conspicuously microreticulate. Prosternal process parallel-sided, as long as prosternum at midline, apex slightly curved inwards. Procoxae subconical, but not extending beyond the level of prosternum. Protibiae expanded at apex, three times as long as broad; long setae concentrated at the second half; external facet with fewer setae. Meso- and metatibiae four times as long as broad and not expanded at apex; outer facet bearing a row of setae, with the longest setae placed close to apex. Metaventrite with a few sparse short setae and small punctures; surface between punctures microreticulate; discrimen about one-fourth the length of metaventrite at midline. Abdominal ventrites microreticulate and with fine sparse punctures, most of them bearing a slender decumbent seta; length of ventrites (in mm, from base to apex at the longitudinal midline) as follows: 0.25, 0.09, 0.09, 0.09, 0.09; first ventrite bearing a slightly oval, margined setose sex patch at its center (Fig. 6), with a transverse diameter of 0.06 mm. Male abdominal terminalia in a paratype (Figs 7–9) with sternite VIII (Fig. 7) subtrapezoidal, the posterior margin slightly sinuous and bearing long slender setae at the sides. Tegmen (Fig. 8) 4.3X as long as wide, subparallel-sided; apical portion subtriangular, delimited by lateral excavations (Fig. 8, arrows) and bearing several sensilla; apex rounded. Penis (Fig. 9) a bit longer than tegmen, about 6X as long as wide and subparallel-sided; apex slightly enlarged and membranous. Females (Fig. 4). Similar to males, but devoid of secondary sexual features (i.e. abdominal sex patch, head plates and occipital tubercle) and surface of head punctate. Females also have an area of higher density of long setae at the anteriormost portion of pronotum, but less conspicuous than in males. Female abdominal terminalia (Fig. 10; spiculum ventrale not shown) with spiculum ventrale near as long as ovipositor. Ovipositor with gonocoxites transversally divided into three parts; apical gonocoxites each bearing a conspicuous stylus (=gonostylus) and an inner protuberance bearing an apical seta (Fig. 10, arrows); paraprocts short, about 0.75X the length of gonocoxites together; proctiger with its opening positioned near the dorsal rim of the second gonocoxites; each paraproctal baculum fused apically with a proctigeral baculum, forming an arc. Variation. All specimens lack part of their legs and antennae and, among all, the male in the best condition was chosen as the holotype. Measurements in mm. Males (n=7, two from Silver Road and 5 from Prince Alfred’s Pass, the last including the holotype): TL 1.29–1.69 (0.14 ± 1.46), PL 0.41–0.64 (0.09 ± 0. 53), PW 0.56–0.80 (0.09 ± 0.69), EL 0.85–1.05 (0.08 ± 0. 94), EW 0.57–0.79 (0.08 ± 0. 69), GD 0.50–0.67 (0.07 ±0.6), EL/PL 1.50–2.12 (0.30± 1.85), GD/ EW 0.86–0.92 (0.03 ± 0. 87), TL/EW 1.98–2.40 (0.14± 2.13). The males vary in size and the biggest ones are from Prince Alfred’s Pass. Biggest males have a bigger tubercle on occiput. There is a conspicuous variation in the number and density of long setae in the anterior portion of pronotum, and these setae are most conspicuous in males from Prince Alfred’s Pass. Females (n=3, all from Prince Alfred’s Pass) TL1.41–1.53 (0.06± 1.46), PL 0.49–0.55 (0.03 ± 0. 52), PW 0.60–0.68 (0.04 ± 0. 65), EL 0.89–1.04 (0.09 ± 0.94), EW 0.06–0.77 (0.06 ± 0. 71), GD 0.56–0.61 (0.02 ± 0. 59), EL/ PL1.76–2.21 (0.24± 2.04), GD/EW 0.81–0.88 (0.03 ± 0.85), TL/EW 2.13–2.16 (0.02± 2.15). Type series. Holotype: Ƌ (SANC) “ SOUTH AFRICA WCAPE Prince Alfred’s Pass N of Knysna 33º 58’S 23º09’E 5.xi.2009 S& OC Neser \ Ex bracket fungus #216 on fallen tree trunk \ Ex bracket fungus Ganoderma applanatum BF# 216 \ NATIONAL COLL. OF INSECTS, Pretoria, South Africa \ Cis regius Orsetti & Lopes-Andrade HOLOTYPUS [red paper]”. Paratypes: 13ƋƋ and 4 ♀♀ (5ƋƋ, 1 dissected, 2♀♀, 1 dissected, CELC; 8ƋƋ, 2♀♀, SANC) “ SOUTH AFRICA WCAPE Prince Alfred’s Pass N of Knysna 33º 58’S 23º09’E 5.xi.2009 S& OC Neser \ Ex bracket fungus #216 on fallen tree trunk \ Ex bracket fungus Ganoderma applanatum BF# 216 \ NATIONAL COLL. OF INSECTS, Pretoria, South Africa \ Cis regius Orsetti & Lopes-Andrade PARATYPUS [yellow paper]”; 2ƋƋ (1 dissected CELC; 1 SANC) “ SOUTH AFRICA: WCAPE Silver R. old Saasveld rod to Wilnerness 33º58’ S 22º33’E 15.viii.1990 A.J. Hendricks \ Emerged from log of Rhus chirundensis ANACARDIACEA UA 637 \ NATIONAL COLL. OF INSECTS, Pretoria, South Africa \ Cis regius Orsetti & Lopes-Andrade PARATYPUS [yellow paper]”.Published as part of Orsetti, Artur & Lopes-Andrade, Cristiano, 2016, Cis regius, a new species of Cis Latreille (Coleoptera: Ciidae) from Southern Africa, pp. 145-150 in Zootaxa 4139 (1) on pages 146-147, DOI: 10.11646/zootaxa.4139.1.12, http://zenodo.org/record/26276
A controlled study on efficacy and egg reappearance period of Ivermectin in donkeys naturally infected with small strongyles
No full textThe aim of the present study was to investigate the efficacy and the egg reappearance period (ERP) of ivermectin (IVM) in donkeys during a 13-week period. The study involved a total of 14 adult Amiata breed donkeys, 7 – 13 years of age, and naturally infected with small strongyles. A group of 10 don- keys was treated with IVM oral paste at a dose rate of 200 mcg/kg BW. Another group of 4 donkeys was kept as untreated control group. Faecal samples were collected and examined for strongyle eggs on day 0 before treatment. IVM efficacy was based on the faecal egg count reduction test (FECRT) on day 14 post-treatment. Then individual faecal samples were collected and examined by FECRT at weekly intervals. A FECRT of 100 % was found after treatment with IVM and its ERP, defined as the week when the mean FECRT decreased until to become lower than 90 % efficacy, was estimated to be 11 weeks without signs of developing anthelmintic resistance. No adverse reac- tions were observed during the study period. Our findings may be useful to veterinary practitioners and breeders as they show that IVM, at the recommended dose rate, can be still considered a highly effective and safe pharmacological tool for the treatment of small strongyles in donkeys. Therefore, it is strongly recommended that all possible strategies are undertaken to avoid the risk of emergence of anthelmintic resistance to IVM in donkeys
Cis regius, a new species of Cis Latreille (Coleoptera: Ciidae) from Southern Africa
No full textOrsetti, Artur, Lopes-Andrade, Cristiano (2016): Cis regius, a new species of Cis Latreille (Coleoptera: Ciidae) from Southern Africa. Zootaxa 4139 (1): 145-150, DOI: http://doi.org/10.11646/zootaxa.4139.1.1
ANALYTICAL EVALUATION AND EXPERIMENTAL TESTS OF JUMP IN SOME LOW-SPEED CAM-FOLLOWER SYSTEMS
No full text
Gli istituti dell’accesso ad atti e documenti delle PPAA e degli organismi a partecipazione pubblica
No full textUna della tematiche di maggior rilievo per gli operatori del comparto pubblico, trattate nel D.Lgs. n. 33/2013 (“Decreto Trasparenza”), è quella dell’accesso civico, che riguarda non solo la possibilità di - stricto sensu - accedere agli atti, ai documenti e alle informazioni che la Pubblica Amministrazione ha l’obbligo di pubblicare nella specifica sezione del sito istituzionale; ma, anche, il riconoscimento a chiunque del “diritto di accedere ai dati e ai documenti detenuti dalle pubbliche amministrazioni, ulteriori rispetto a quelli oggetto di pubblicazione ...”. Una possibilità, questa, decisamente estesa sulla carta, ma che incontra, però, precisi limiti legislativi e interpretativi che complicano i processi istruttori, volti a valutare l’accoglimento o meno delle istanze di accesso provenienti da terzi, da parte del Responsabile della Trasparenza o del soggetto specificatamente individuato quale responsabile dell’accesso civico nelle PP.AA. e negli Organismi a partecipazione pubblica (che sottostanno alla normativa sulla trasparenza anche in forza di quanto stabilito dalla Delibera ANAC 8 novembre 2017, n. 1134 “Nuove linee guida per l’attuazione della normativa in materia di prevenzione della corruzione e trasparenza da parte delle società e degli enti di diritto privato controllati e partecipati dalle pubbliche amministrazioni e degli enti pubblici economici.
FIGURES 1–6 in Cis regius, a new species of Cis Latreille (Coleoptera: Ciidae) from Southern Africa
No full textFIGURES 1–6. Cis regius Orsetti & Lopes-Andrade sp. nov., adult male holotype (1–3, 5–6) 1. Dorsal view. 2. Lateral view. 3. Ventral view 4. Female paratype, dorsal view 5. Detail of male head showing the anterior subtriangular plates (small arrows) and a tubercle at the anterior portion of occiput (big arrow) 6. Male sex patch at the first abdominal ventrite. Scale bars: 0.5 mm (1–4); 0.1 mm (5–6).Published as part of Orsetti, Artur & Lopes-Andrade, Cristiano, 2016, Cis regius, a new species of Cis Latreille (Coleoptera: Ciidae) from Southern Africa, pp. 145-150 in Zootaxa 4139 (1) on page 148, DOI: 10.11646/zootaxa.4139.1.12, http://zenodo.org/record/26276
Pathogenetic mechanisms in motor neuron diseases
No full textAmyotrophic Lateral Sclerosis, ALS, and Spinal and Bulbar Muscular Atrophy, SBMA (or Kennedy’s disease, KD) are two rare degenerative disorders of nervous system, characterized by early involvement of motor neurons. ALS is characterized by degeneration and death of upper and lower motor neurons, which leads to generalized muscle weakness and atrophy, speech and swallowing disabilities, and progressive paralysis until death is caused by respiratory failure. Its pathogenesis is still unknown. KD is an inherited X-linked motor neuronal disorder caused by an abnormal expansion of a trinucleotide CAG repeat in the first coding exon of the androgen receptor (AR) gene and resulting in an extended polyglutamine AR protein. The main clinical features of KD are proximal limb and bulbar muscle weakness and atrophy.
The present study develops two principal topics on these two motor neuron diseases and aims to understand pathogenetic mechanisms for diagnostic, prognostic and treatment purposes.
In our cohort of ALS patients, we evaluate skeletal muscle as possible biomarker site, through the analysis of TDP-43 protein in 30 muscle biopsies; we found no pathological alterations and we concluded that TDP-43 pathology is not to be considered a systemic feature. We also screened 222 ALS patients for TARDBP and FUS/TLS genes mutations involved in the pathogenesis of ALS; we found two known mutations in TARDBP and we could contributed to confirm the frequencies in ALS population. Lastly, we genotyped SNP rs1541160 of KIFAP3 gene in 228 ALS patients and we could assess a relationship between the minor CC genotype and the upper motor neuron-dominant ALS phenotype.
Concerning KD, we aimed to investigate whether the myopathy could start at muscular level and caused by the mutant polyQ-AR, which is toxic when accumulate into the nucleus. We evaluated differentiation and maturation ability of satellite cells from four KD patients, cultured with or without androgen (Dihydrotestosterone, DHT) treatment; we also assessed polyQ-AR localization in KD satellite cells and 10-day differentiated myotubes, with/without DHT treatment. The results showed a marked atrophy in KD myotubes that could be assigned to mutant polyQ-AR since it was observed significantly increase in KD myotube nuclei compared to controls. This confirmed the primitive muscular involvement in KD.La Sclerosi Laterale Amiotrofica, SLA, e l’Atrofia Muscolare Spinobulbare (o malattia di Kennedy, KD) sono due rari disturbi degenerativi del sistema nervoso, caratterizzati da un precoce coinvolgimento dei neuroni motori. La SLA è caratterizzata da degenerazione e morte di motoneuroni superiori e inferiori, che comporta debolezza muscolare generalizzata e atrofia, incapacità di parlare e deglutire, e progressiva paralisi fino alla morte, causata da arresto respiratorio. La sua patogenesi è ancora sconosciuta. La KD è un disturbo ereditario legato al cromosoma X dei neuroni motori, causato da un’anormale espansione del trinucleotide CAG nel primo esone codificante del gene del recettore degli androgeni (AR), il quale risulta in una proteina con un più esteso tratto di poliglutammine. Le principali caratteristiche cliniche sono debolezza muscolare bulbare e degli arti prossimali.
Il presente studio sviluppa due principali argomenti su queste due malattie dei motoneuroni, allo scopo di comprenderne i meccanismi patogenetici utili per fini diagnostici, prognostici e terapeutici.
Nella nostra coorte di pazienti SLA, abbiamo valutato il muscolo scheletrico come possibile sito per un biomarcatore, attraverso l’analisi della proteina TDP-43 in 30 biopsie muscolari; non sono state trovate alterazioni patologiche e questo ci ha permesso di concludere che le patologie da TDP-43 non si possono considerare sistemiche. Abbiamo anche screenato 222 pazienti SLA per mutazioni nei geni TARDBP e FUS/TLS che potessero essere coinvolte nella patogenesi della malattia; abbiamo trovato due pazienti con la stessa mutazione in TARDBP e abbiamo potuto confermarne le frequenze nella popolazione SLA. Infine, abbiamo genotipizzato lo SNP rs1541160 del gene KIFAP3 in 228 pazienti SLA e abbiamo potuto stabilire una forte relazione tra il genotipo minore CC e un particolare fenotipo SLA, upper motor neuron-dominant ALS.
Per quanto riguarda la KD, lo scopo dello studio è stato quello di capire se la miopatia poteva scaturire a livello muscolare (anziché essere conseguenza della denervazione) ed essere causata da AR mutato (polyQ-AR), il quale è noto per essere tossico quando accumula nel nucleo della cellula. Abbiamo valutato le capacità di differenziamento e di maturazione delle cellule satelliti di quattro pazienti KD, tenute in coltura con e senza trattamento androginico con Dihydrotestosterone (DHT); abbiamo anche valutato la localizzazione di polyQ-AR nelle cellule satelliti e nei miotubi dopo 10 giorni di differenziamento, con/senza trattamento con DHT. I risultati hanno mostrato una marcata atrofia nei miotubi KD in confronto con controlli sani, che può essere attribuita alla presenza di AR mutato dato che la proteina polyQ-AR era maggiormente espressa nei nuclei dei miotubi KD rispetto ai controlli. Questo conferma il coinvolgimento primario nel muscolo nella KD
- …
