93 research outputs found

    Author Correction: RNAs coordinate nuclear envelope assembly and DNA replication through ELYS recruitment to chromatin

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    In the original version of this Article, the affiliation details for Antoine Aze, Michalis Fragkos, Stéphane Bocquet, Julien Cau and Marcel Méchali incorrectly omitted ‘CNRS and the University of Montpellier’. This has now been corrected in both the PDF and HTML versions of the Article.</jats:p

    A child of the Academy? : investigating Euclid's philosophical background

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    A prevalent idea among contemporary scholars is that Euclid belonged to, or was heavily influenced by the Platonic philosophical tradition. To a certain extent, this impression is not new; the quest for Euclid's philosophical background was probably triggered and enhanced by his late commentators, Greeks and Arabs, who appear confident that he had one. For instance, al-Qifti writes: 'Euclid...called the author of geometry, a philosopher of somewhat ancient date...' and al-Nadim in the Fihrist names Euclid as '...one of the mathematical philosophers...' Proclus, five centuries earlier than al-Nadim, was more specific: '[Euclid] was a follower of Plato by choice, and familiar with this philosophy'. In this paper, I propose to explore the extant accounts on Euclid's philosophical background. (Michalis Sialaros, University of London

    Post - Independence Cypriot Dramaturgy (1960 Onwards)

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    How did playwriting evolve in Cyprus since independence (1960 and afterwards)? There&nbsp;is a systematic absence of studies on the subject. The author of this article analyzes the work&nbsp;of some of the most important playwrights of the period (Rina Katselli, Michalis Pitsillidis,&nbsp;Panos Ioannidis, Michalis Pasiardis and Yiorgos Neophytou) and describes their main&nbsp;carcteristics. Even though the writers of the 1960s continue to write in the naturalistic mode,&nbsp;others courageously follow more contemporary trends.How did playwriting evolve in Cyprus since independence (1960 and afterwards)? There&nbsp;is a systematic absence of studies on the subject. The author of this article analyzes the work&nbsp;of some of the most important playwrights of the period (Rina Katselli, Michalis Pitsillidis,&nbsp;Panos Ioannidis, Michalis Pasiardis and Yiorgos Neophytou) and describes their main&nbsp;carcteristics. Even though the writers of the 1960s continue to write in the naturalistic mode,&nbsp;others courageously follow more contemporary trends.Comment évolue l’écriture théâtrale pendant la période de l’indépendance (depuis 1960)?&nbsp;Il n’existe pas d’études systématiques sur ce sujet. Dans cet article sont analysées des œuvres&nbsp;de quelques auteurs dramatiques les plus représentatifs (Rina Katselli, Michalis Pitsillidis,&nbsp;Panos Ioannidis, Michalis Pasiardis et Yiorgos Neophytou) et sont résumées les lignes&nbsp;directrices de leur œuvre. Bien que les auteurs de la décennie 1960 continuent de créer en&nbsp;suivant la tradition du théâtre éthographique (théâtre de mœurs), on assiste à des efforts plus&nbsp;audacieux, qui tendent à une écriture théâtrale plus contemporaine

    Inverse identification of buffeting and self-excited wind loads on the hardanger bridge from acceleration data

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    The traditional wind load assessment for long-span bridges rely on assumed models for the wind field and aerodynamic coefficients from wind tunnel tests, which usually introduces some uncertainties. It is therefore desired to develop tools that can utilize full-scale vibration response data from existing bridges in order to study the wind loading in detail for in-situ conditions. This paper presents a novel case study of inverse identification of dynamic wind loads on the 1310 m long Hardanger bridge, a suspension bridge equipped with a network of accelerometers. The identification method used is an extented Kalman-type filter for joint input, state, and parameter estimation. A system model considering the still-air modes in addition to a quasi-steady submodel for the self-excited forces of the bridge is presente. The coefficients for self-excited lift and pitching moment are considered unknown and are jointly estimated with the buffeting forces.Dynamics of StructuresOffshore Engineerin

    The Reader as Author and the Ontological Divide: Rome Total War™ and the Semiotic Process

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    The aim of this paper is to focus on some crucial problems concerning the understanding of the new cultural form called "computer games". There are affinities between most computer games (at least the most popular ones) and the literary or cinematic text in that a story of some sort is in­volved in all of them. In the comparison between cinema texts and com­puter games there is even the shared modality of an audiovisual mode of representation.However, there is a great deal of difference in the way the reader / viewer in literature and cinema and the player in computer games interacts with the respective text in question: modes of identification with characters, immersion in the fictional and game world, passive or more active degrees of interaction, etc. The question is whether semiotics as a viable method­ology can assist in the explication of such textual relationships where the player (as reader of her text) assumes authorial characteristics and to what extent such activity affects the ontological status of player (as reader-cum- author) vis-a-vis the real / fictive gameworld. To limit my scope I elect to examine simulation and strategy games, also called "god-games", which offer an omniscient third-person point of view and a flat grid-like gameworld; in particular I focus on a strategy, turn based, simulation game, Rome Total War™, which offers an additional research parameter, that of History

    Optimized design for grating-coupled waveguide-enhanced Raman spectroscopy

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    We report a new design optimization process for planar photonic waveguides applied to waveguide-enhanced Raman spectroscopy (WERS) that combines the optimization of both the surface intensity performance and the grating coupling efficiency. We consider the impact of film thickness on the grating coupling efficiency of two materials with different refractive indices, namely tantalum pentoxide (Ta2O5) and silicon (Si). We propose a new figure-of-merit (FOM) that takes into account both the coupling efficiency and surface intensity dependence for Raman excitation on the film thickness. Our study shows that the optimum surface-sensitive waveguide thickness is thinner than the optimum coupling efficiency thickness for both material systems. As an example, for a tantalum pentoxide waveguide operating at 785 nm, our optimization strategy proposes a 20% increase in waveguide core thickness relative to the optimum surface-sensitive thickness to achieve the best performance in WERS applications. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI

    Art History and Karaoke: Six Hands and a Cheese Sandwich

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    We cannot precisely say what is not appropriation. Impossible to draw a categorical line. Appropriation is practiced everywhere and all the time, also by people who never have heard the word. As someone said before, no author has his complete meaning alone

    Closed cavity façade, an innovative energy saving façade

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    In its simplest form, a Closed Cavity Façade (CCF) consists of a double or triple glazing unit (DGU or TGU) on the inner layer and single glazing on the outer one, forming a sealed non-ventilated cavity with an automated shading device in between. Given its dynamic behaviour, this technology can dynamically control the flow of solar energy and light penetrating the building. Using EnergyPlus and IDA ICE, several CCF configurations were investigated and compared to the baseline (TGU). MATELab, an office-like test facility at the University of Cambridge, was used as the model, which was beforehand experimentally validated. The results show extensive benefits of CCFs compared to traditional TGU systems, in terms of thermal performance and occupants’ comfort. The CCF configurations investigated led to an improvement of energy performance in the range of 18–37% compared to the traditional TGU, depending on the CCF configuration and the climate while a previous study, using CCF configurations with DGU as inner skin, revealed an improvement of energy performance in the range of 22–41% compared to the conventional DGU. Further investigation showed that glass coatings and solar shading characteristics play an important role in cutting down overheating phenomenon while increasing occupants’ comfort. Practical application: Governments are making ever more stringent energy regulations for the building industry aiming to reduce energy consumption and carbon emissions. At the same time, building owners and architects are looking at cost-effective solutions for the long-term performance of buildings while tenants/occupants are more than ever aware of the fact that building comfort increases well-being and productivity. In all these regards, this work focuses and accentuates that substantial improvements can be achieved by designing and using suitable configurations of the innovative Closed Cavity Façade according to the climatic conditions of each location. The results presented indicate that there is much potential in improving the energy and comfort performance of a building, raising awareness to help deploy innovative glazing technologies.Structural Design & Mechanic

    Multi-port DC hub based on the Modular Multilevel Converter for Multi-terminal HVDC grids

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    It is expected that DC grids will evolve into large meshed networks, which will have multiple DC voltage levels. Two DC grids operating at different voltage levels could be interconnected using a DC-DC converter. The role of the DC-DC converter in meshed DC networks is similar to the role of a transformer in traditional AC systems. The DC-DC converter could take a range of functions in DC grids. The DC-DC converter should prevent the propagation of DC faults and should also have the ability to isolate DC faults. Because of its high cost, the DC-DC converter cannot be used as DC breaker in meshed DC grids, but it can be strategically placed in the DC grid to provide protection zone separation. In case multiple HVDC (High Voltage Direct Current) lines need to be interconnected, a multiport DC-DC converter should be used. The DC hub is a multiport DC/DC converter which consists of an inner AC circuit and AC/DC converters interfacing each HVDC line. The main goal of the DC hub is the interconnection of multiple HVDC lines operating at different voltage levels and with different DC grid configurations.In this thesis, the operation of a DC hub based on the MMC (Modular Multilevel Converter) converter was investigated. A three-port MMC-based DC hub was simulated using Matlab/Simulink. An important contribution of this thesis is a comparison of different DC hub topologies which could be used for the interconnection of multiple HVDC lines. Several designs for the inner AC circuit are suggested and the advantages and disadvantages of each recommended design are described in detail. Furthermore, a methodology is presented for the clearing of AC faults within the DC hub and the protection of the system during the fault. An AC fault within the DC hub should be cleared by opening the AC circuit breaker of the faulted port. A methodology is also presented for the safe connection or disconnection of additional ports from the DC hub. Any port should be easily connected or disconnected from the DC hub without affecting the operation of the other ports. The DC hub should also offer connection points to allow the interconnection of more ports. Finally, the operation of the DC hub is investigated when generation or consumption units are connected to its inner AC circuit. In case the DC hub is used for the interconnection of multiple offshore HVDC cables, the loads of the offshore platform or a nearby offshore wind farm could be directly connected to its inner AC circuit. With the concepts analysed in this thesis, HVDC network system designers will be able to select the most suitable DC hub topology for the interconnection of multiple HVDC lines, use a methodology for the clearing of AC faults within the DC hub, use a methodology for the safe connection or disconnection of ports and understand the design limitations of the DC hub when generation or consumption units are connected to its AC side
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