1,832 research outputs found
The Development Impact of Information Technology in Trade Facilitation
Get PDFThe main purpose of this chapter is to provide an overview and context of the country studies on Information Technology (IT) for Trade Facilitation (TF) in Small and Medium Enterprises (SMEs).Impact of Information Techonology, Trade Facilitation, SMEs
Evaluation of ITER TF Coil Joint Performance
Get PDFTo evaluate the ITER TF joint performance, the joint test sample, which consists of two short TF conductors and has full size joint, shall be tested using NIFS test facility under the condition of current of 68 kA and external field of 2 T. For high accuracy, the issue of voltage difference between cable and jacket had been anticipated in the evaluation of joint resistance. If a voltage difference exist between them, it is difficult to measure real joint resistance using voltage taps on the jacket. Therefore, the author first calculated the position where voltage of cable and jacket become equipotential and then decided the voltage tap position where the influence of voltage drop could be avoided. Thus, a high accuracy measurement of joint resistance could be achieved and the joint resistance was accurately evaluated as around 1 n Ω , which is well below the ITER requirement of 3 n Ω .journal articl
The hypergeometric test performs comparably to TF-IDF on standard text analysis tasks
No full textTerm frequency-inverse document frequency, or TF-IDF for short, and its many variants form a class of term weighting functions the members of which are widely used in text analysis applications. While TF-IDF was originally proposed as a heuristic, theoretical justifications grounded in information theory, probability, and the divergence from randomness paradigm have been advanced. In this work, we present an empirical study showing that TF-IDF corresponds very nearly with the hypergeometric test of statistical significance on selected real-data document retrieval, summarization, and classification tasks. These findings suggest that a fundamental mathematical connection between TF-IDF and the negative logarithm of the hypergeometric test P-value (i.e., a hypergeometric distribution tail probability) remains to be elucidated. We advance the empirical analyses herein as a first step toward explaining the long-standing effectiveness of TF-IDF from a statistical significance testing lens. It is our aspiration that these results will open the door to the systematic evaluation of significance testing derived term weighting functions in text analysis applications
Who said that? Comparing performance of TF-IDF and fastText to identify authorship of short sentences
No full textAuthorship identification is often applied to large documents, but less so to short, everyday sentences. The ability of identifying who said a short line could provide help to chatbots or personal assistants. This research compares performance of TF-IDF and fastText when identifying authorship of short sentences, by applying these feature extraction techniques to the television series Friends' transcripts. TF-IDF outperforms fastText in every measurement, but its performance is only marginally better than randomly guessing the original character, reaching an accuracy of 28 percent when making a distinction between 6 characters. Accuracy increases linearly at the same rate for both techniques as the minimum word count per sentence set on the test data increases. TF-IDF's confidence remains constant as this limit is set on either the test or training data, whereas fastText's confidence decreases and increases, respectively. Cross-entropy loss, however, remains constant for fastText and decreases for TF-IDF as the minimum word count set on the test data increases.CSE3000 Research ProjectComputer Science and Engineerin
Evaluation of ITER TF Coil Joint Performance
No full textTo evaluate the ITER TF joint performance, the joint test sample, which consists of two short TF conductors and has full size joint, shall be tested using NIFS test facility under the condition of current of 68 kA and external field of 2 T. For high accuracy, the issue of voltage difference between cable and jacket had been anticipated in the evaluation of joint resistance. If a voltage difference exist between them, it is difficult to measure real joint resistance using voltage taps on the jacket. Therefore, the author first calculated the position where voltage of cable and jacket become equipotential and then decided the voltage tap position where the influence of voltage drop could be avoided. Thus, a high accuracy measurement of joint resistance could be achieved and the joint resistance was accurately evaluated as around 1 n Ω , which is well below the ITER requirement of 3 n Ω
Pancreatic ß-cells activate a JunB/ATF3-dependent survival pathway during inflammation
No full textDestruction of insulin-producing pancreatic β-cells by local autoimmune inflammation is a hallmark of type 1 diabetes. Histochemical analysis of pancreases from non-obese diabetic mice indicated activation of the transcription factor JunB/AP-1 (activator protein-1) after autoimmune infiltration of the islets. In vitro studies demonstrated that the cytokines tumor necrosis factor (TNF)-α and interferon (IFN)-γ induce JunB expression as a protective mechanism against apoptosis in both human and rodent β-cells. The gene network affected was studied by microarray analysis showing that JunB regulates nearly 20% of the cytokine-modified β-cell genes, including the transcription factor ATF3. Direct transcriptional induction of ATF3 by JunB is a key event for β-cell survival after TNF-α+IFN-γ treatment. Moreover, pharmacological upregulation of JunB/ATF3 via increased cAMP protected rodent primary β-cells and human islet cells against pro-inflammatory mediators. These results were confirmed in genetically modified islets derived from Ubi-JunB transgenic mice. Our findings identify ATF3 as a novel downstream target of JunB in the survival mechanism of β-cells under inflammatory stress.Oncogene advance online publication, 15 August 2011; doi:10.1038/onc.2011.353
Construction of an adult barnacle (Balanus amphitrite) cDNA library and selection of reference genes for quantitative RT-PCR studies
Get PDFDe Gregoris TB, Borra M, Biffali E, et al. Construction of an adult barnacle (Balanus amphitrite) cDNA library and selection of reference genes for quantitative RT-PCR studies. BMC Molecular Biology. 2009;10(1):62.BACKGROUND:
Balanus amphitrite is a barnacle commonly used in biofouling research. Although many aspects of its biology have been elucidated, the lack of genetic information is impeding a molecular understanding of its life cycle. As part of a wider multidisciplinary approach to reveal the biogenic cues influencing barnacle settlement and metamorphosis, we have sequenced and annotated the first cDNA library for B. amphitrite. We also present a systematic validation of potential reference genes for normalization of quantitative real-time PCR (qRT-PCR) data obtained from different developmental stages of this animal.
RESULTS:
We generated a cDNA library containing expressed sequence tags (ESTs) from adult B. amphitrite. A total of 609 unique sequences (comprising 79 assembled clusters and 530 singlets) were derived from 905 reliable unidirectionally sequenced ESTs. Bioinformatics tools such as BLAST, HMMer and InterPro were employed to allow functional annotation of the ESTs. Based on these analyses, we selected 11 genes to study their ability to normalize qRT-PCR data. Total RNA extracted from 7 developmental stages was reverse transcribed and the expression stability of the selected genes was compared using geNorm, BestKeeper and NormFinder. These software programs produced highly comparable results, with the most stable gene being mt-cyb, while tuba, tubb and cp1 were clearly unsuitable for data normalization.
CONCLUSION:
The collection of B. amphitrite ESTs and their annotation has been made publically available representing an important resource for both basic and applied research on this species. We developed a qRT-PCR assay to determine the most reliable reference genes. Transcripts encoding cytochrome b and NADH dehydrogenase subunit 1 were expressed most stably, although other genes also performed well and could prove useful to normalize gene expression studies
Extracting location context from transcripts: a comparison of ELMo and TF-IDF
No full textUsing transcripts of the TV-series FRIENDS, this paper explores the problem of predicting the location in which a sentence was said. The research focuses on using feature extraction on the sentences, and training a logistic regression model on those features. Specifically looking at the differences in performance between using ELMo and TF-IDF for this feature extraction, achieving an accuracy rate of 58\% and 67\% respectively on a binary classification. The paper also explores the effect of several data cleaning techniques on the results. Git repository containing the source code used in the paper - https://github.com/David-Happel/scene-location-NLPCSE3000 Research ProjectComputer Science and Engineerin
Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasivge phenotype of RET/PTC-transformed thyroid cells
No full textPapillary thyroid carcinomas are characterized by rearrangements of the RET receptor tyrosine kinase generating RET/ PTC oncogenes. Here we show that osteopontin ( OPN), a secreted glycoprotein, is a major RET/ PTC- induced transcriptional target in PC Cl 3 thyroid follicular cells. OPN upregulation depended on the integrity of the RET/ PTC kinase and tyrosines Y1015 and Y1062, two major RET/ PTC autophosphorylation sites. RET/ PT C also induced a strong overexpression of CD44, a cell surface signalling receptor for OPN. Upregulation of CD44 was dependent on RET/ PTC Y1062, as well. Constitutive OPN overexpression or treatment with exogenous recombinant OPN sharply increased proliferation, Matrigel invasion and spreading in collagen gels of RET/ PTC- transformed PC Cl 3 cells. These effects were impaired by the treatment of PC Cl 3- RET/ PTC cells with OPN- and CD44- blocking antibodies. Thus, RET/ PTC signalling triggers an autocrine loop involving OPN and CD44 that sustains proliferation and invasion of transfomed PC Cl 3 thyrocytes
Author identification system
No full textAbstract: Every one of us has different approach to speak and write, and there exists a long history of linguistic and stylistic analysis into authorship attribution. In last year’s, practical application for author identification have grown in area such as computer forensic(linking intercepted message to each other and to find rebel), criminal law(identifying author of payoff notes and harassing letter), civil law and computer security (tracking author of computer source code). This paper proposes the implementation of author identification system. This proposed system is based upon the principles and concepts of text analysis. For ensuring maximum accuracy in identifying author of the document we will be using TF-IDF algorithm which consists of extraction of features from the text, scoring these features and comparing them with a set of scores stored in the corpus
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