70,536 research outputs found
Inventory of the Salt Lake Organizing Committee for the Olympic Winter Games records
No full textComplete inventory of the contents of the boxes within the Salt Lake Organizing Committee for the Olympic Winter Games records. This inventory provides a thorough listing of all the materials contained in all cartons and folder
Exploring the role of tryptamine and serotonin in tomato reproductive development
No full textTryptamine (TAM) and serotonin (SER) are two compounds derived from tryptophan that belong to a widespread class of bioactive molecules known as indolamines or indole alkaloids. In plants, TAM and SER are primarily recognized as intermediates in the biosynthesis of melatonin, a well-studied molecule involved in crucial biological processes such as responses to biotic and abiotic stress, reactive oxygen species (ROS) scavenging, embryo development, and plant morphogenesis. Although TAM and SER have been detected at high concentrations (μg/g of fresh weight) in the edible fruits and seeds of numerous plant species, their biological functions in reproductive organs remain unclear, and their metabolic pathways still need to be fully elucidated. The biosynthesis of TAM and SER in plants typically involves consecutive decarboxylation and hydroxylation reactions of tryptophan, catalyzed by the enzymes tryptophan decarboxylase (TDC) and tryptamine 5-hydroxylase (T5H), respectively. Our recent research has focused on the functional characterization of a three-member TDC gene family and a single T5H gene involved in the biosynthesis of TAM and SER in the model species Solanum lycopersicum. Our findings support a model in which SlTDC1 promotes TAM accumulation in fruits, SlTDC2 mediates TAM production in aerial vegetative organs, SlTDC3 drives TAM synthesis in roots and seeds, and SlT5H is responsible for the conversion of TAM to SER throughout the plant (Commisso et al., 2022). Currently, our research aims to unravel the biological functions of these two indolamines in various organs and tissues of the tomato plant. We have implemented a metabolic engineering approach, utilizing both traditional transgenesis and CRISPR/Cas9-mediated gene knockout, to generate different tomato genotypes characterized by altered levels of TAM and SER. Phenotypic characterization of SlTDC1-overexpressing lines and SlTDC1-knockout mutants revealed significant and consistent changes in the number and dimensions of ripe fruits compared to the wild-type genotype. Furthermore, seeds from sldtc1 lines exhibited altered seed coat pigmentation and a consistent reduction in germination capacity. Overall, these findings suggest a potential role for TAM and SER in reproductive development
Letter from [Organizing Committee of The Explorers\u27 Club] to John Muir, 1904 May 12.
Get PDFMay 12th, 1904.Dear Sir:-An Association is to be formed in New York City to be known as the Explorers\u27 Club, whose objects shall be to unite explorers in the bonds of good-fellowship, and to promote the work of exploration by every means in its power.With this end in view, a meeting and a banquet will he held on Saturday evening, May 28th, at seven o\u27clock, at the Aldine Association rooms, 111 Fifth Avenue, for the purpose of forming a permanent organization, and of electing officers.The undersigned, who are acting as a Committee on Organization, cordially invite you to be present at the banquet and meeting thereafter, and to co-operate in organizing the club. The banquet will cost $2.50 per plate, which may be paid for on the evening of the meeting. It is understood that the dues will be kept at a moderate figure, not to exceed five dollars per annum.Please send a reply to this communication at your earliest convenience to the acting Secretary, Henry Collins Walsh - 452 Fifth Avenue - New York City.Hoping that we shall have the pleasure of your company on the occasion mentioned, we have the honor to remain,Yours very truly,Gen. A. W. Greely,Donaldson Smith,Prof. Carl Lumholtz, Dr. F. A. Cook,Prof. Marshall Seville,F. S. Dellenbaugh,Caspar Whitney,Dr. Wm. H. Furness,Henry Collins Walsh.[03354]https://scholarlycommons.pacific.edu/jmcl/28843/thumbnail.jp
R.O.C. Messenger: February 1948
Get PDFFebruary 1948. Published by the Republican Organizing Committee, this issue of the R.O.C. Messenger consists of 8 pages of text. Volume 2, Number
R.O.C. Messenger, September 1945
Get PDFSeptember 1945. Published by the Republican Organizing Committee, this issue of The R.O.C. Messenger consists of 8 pages of text. Volume 1, Number
R.O.C. Messenger: June 1946
Get PDFJune 1946. Published by the Republican Organizing Committee, this issue of the R.O.C. Messenger consists of 8 pages of text. Volume 1, Number 1
R.O.C. Messenger: March 1948
Get PDFMarch 1948. Published by the Republican Organizing Committee, this issue of the R.O.C. Messenger consists of 8 pages of text. Volume 2, Number
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