111 research outputs found
A conversation with Selma Dabbagh
This is an interview with British-Palestinian writer, lawyer and activist Selma Dabbagh, who is the author of a novel, Out of It (2011), a number of short stories and a radio play produced by the BBC, as well as numerous reviews and blogs. Out of It is set in Gaza, the Gulf and London and will be published in Arabic translation in 2014. In this conversation, which began at Lancaster University in November 2013 and extended via email over the next two months, Dabbagh discusses her motivations for, and the challenges of, setting her fiction in parts of the Middle East, in particular Palestine. She comments on her “British-Palestinian” identity and the increasing visibility of Palestinian writing in English and explores the relationship between literary writing, in particular the novel, history and politics
sj-docx-2-han-10.1177_15589447231198268 – Supplemental material for Outcomes Following Surgical Interventions for Isolated Lunotriquetral Interosseous Ligament Injuries: A Systematic Review
Supplemental material, sj-docx-2-han-10.1177_15589447231198268 for Outcomes Following Surgical Interventions for Isolated Lunotriquetral Interosseous Ligament Injuries: A Systematic Review by Mohanad Omar-Hossein, Jacob C. K. Leung, Joyce Munaku, Danielle Rodzik, Armaghan Dabbagh and Mike Szekeres in HAND</p
sj-docx-1-han-10.1177_15589447231198268 – Supplemental material for Outcomes Following Surgical Interventions for Isolated Lunotriquetral Interosseous Ligament Injuries: A Systematic Review
Supplemental material, sj-docx-1-han-10.1177_15589447231198268 for Outcomes Following Surgical Interventions for Isolated Lunotriquetral Interosseous Ligament Injuries: A Systematic Review by Mohanad Omar-Hossein, Jacob C. K. Leung, Joyce Munaku, Danielle Rodzik, Armaghan Dabbagh and Mike Szekeres in HAND</p
Three Encounters on the West Bank
The Palestine Festival of Literature was established in 2008. Bringing together writers from all corners of the globe, it aims to help Palestinians break the cultural siege imposed by the Israeli military occupation, to strengthen their artistic links with the rest of the world, and to reaffirm, in the words of Edward Said, 'the power of culture over the culture of power'.
Celebrating the tenth anniversary of PalFest, This Is Not a Border is a collection of essays, poems and stories from some of the world's most distinguished artists, responding to their experiences at this unique festival. Both heartbreaking and hopeful, their gathered work is a testament to the power of literature to promote solidarity and courage in the most desperate of situations.
Contributors: Susan Abulhawa, Suad Amiry, Victoria Brittain, Jehan Bseiso, Teju Cole, Molly Crabapple, Selma Dabbagh, Mahmoud Darwish, Najwan Darwish, Geoff Dyer, Yasmin El-Rifae, Adam Foulds, Ru Freeman, Omar Robert Hamilton, Suheir Hammad, Nathalie Handal, Mohammed Hanif, Jeremy Harding, Rachel Holmes, John Horner, Remi Kanazi, Brigid Keenan, Mercedes Kemp, Omar El-Khairy, Nancy Kricorian, Sabrina Mahfouz, Jamal Mahjoub, Henning Mankell, Claire Messud, China Miéville, Pankaj Mishra, Deborah Moggach, Muiz, Maath Musleh, Michael Palin, Ed PavliçAtef Abu Saif, Kamila Shamsie, Raja Shehadeh, Gillian Slovo, Ahdaf Soueif, Linda Spalding, Will Sutcliffe, Alice Walker
With messages from China Achebe, Michael Ondaatje and J. M. Coetze
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis in a young lebanese girl
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a recently recognized autoimmune neurologic disorder that presents with severe neuropsychiatric symptoms in previously healthy children. A 4-year-old Lebanese girl presented with new-onset behavioral changes, orofacial dyskinesias, fluctuation in consciousness, inability to walk, and mutism. Antibodies directed against NMDA receptors were detected in the patient's serum and cerebrospinal fluid. Prompt treatment with a single course of intravenous immunoglobulin resulted in early complete recovery. This is the first case report of a Middle Eastern child affected with this condition. © The Author(s) 2012.Braakman HMH, 2010, NEUROLOGY, V75, pE44, DOI 10.1212-WNL.0b013e3181f11dc1; Chapman MR, 2011, AM J PSYCHIAT, V168, P245, DOI 10.1176-appi.ajp.2010.10020181; Dalmau J, 2011, LANCET NEUROL, V10, P63, DOI 10.1016-S1474-4422(10)70253-2; Dalmau J, 2008, LANCET NEUROL, V7, P1091, DOI 10.1016-S1474-4422(08)70224-2; Dalmau J, 2007, ANN NEUROL, V61, P25, DOI 10.1002-ana.21050; Domingues RB, 1998, J CLIN MICROBIOL, V36, P2229; Florance NR, 2009, ANN NEUROL, V66, P11, DOI 10.1002-ana.21756; Gable MS, 2009, EUR J CLIN MICROBIOL, V28, P1421, DOI 10.1007-s10096-009-0799-0; Irani SR, 2010, BRAIN, V133, P1655, DOI 10.1093-brain-awq113; Luca N, 2011, ARTHRITIS RHEUM-US, V63, P2516, DOI 10.1002-art.30437; Poloni C, 2010, DEV MED CHILD NEUROL, V52, pe78, DOI 10.1111-j.1469-8749.2009.03542.x; Tyler Kenneth L, 2004, Rev Neurol Dis, V1, P169; Verhelst H, 2011, EUR J PAEDIATR NEURO, V15, P163, DOI 10.1016-j.ejpn.2010.07.004; Wandinger KP, 2011, J NEUROIMMUNOL, V231, P86, DOI 10.1016-j.jneuroim.2010.09.0120
sj-docx-1-jicm-10.1177_08850666211053548 - Supplemental material for The Role of Inhaled Corticosteroids (ICS) in Critically Ill Patients With COVID-19: A Multicenter, Cohort Study
Supplemental material, sj-docx-1-jicm-10.1177_08850666211053548 for The Role of Inhaled Corticosteroids (ICS) in Critically Ill Patients With COVID-19: A Multicenter, Cohort Study by Khalid Al Sulaiman, Ohoud Aljuhani, Kholoud Al Aamer, Omar Al Shaya, Abdulrahman Al Shaya, Alawi S. Alsaeedi, Alaa Alhubaishi, Ali F. Altebainawi, Alaa Al Harthi, Shorouq Albelwi, Rahaf Almutairi, Norah Alsubaie, Alanoud Alsallum, Ghazwa B. Korayem, Amjaad Alfahed, Raed Kensara, Elaf F. Altebainawi, Raghdah S. Alenezi, Thamer Alsulaiman, Huda Al Enazi, Ramesh Vishwakarma, Tarek Al Dabbagh, Umar Bakhsh and Ghassan Al Ghamdi in Journal of Intensive Care Medicine</p
Lethal digenic mutations in the K<sup>+</sup> channels Kir4.1 (<i>KCNJ10</i>) and SLACK (<i>KCNT1</i>) associated with severe-disabling seizures and neurodevelopmental delay
A 2-yr-old boy presented profound developmental delay, failure to thrive, ataxia, hypotonia, and tonic-clonic seizures that caused the death of the patient. Targeted and whole exome sequencing revealed two heterozygous missense variants: a novel mutation in the KCNJ10 gene that encodes for the inward-rectifying K+ channel Kir4.1 and another previously characterized mutation in KCNT1 that encodes for the Na+-activated K+ channel known as Slo2.2 or SLACK. The objectives of this study were to perform the clinical and genetic characterization of the proband and his family and to examine the functional consequence of the Kir4.1 mutation. The mutant and wild-type KCNJ10 constructs were generated and heterologously expressed in Xenopus laevis oocytes, and whole cell K+ currents were measured using the two-electrode voltage-clamp technique. The KCNJ10 mutation c.652C>T resulted in a p.L218F substitution at a highly conserved residue site. Wild-type KCNJ10 expression yielded robust Kir current, whereas currents from oocytes expressing the mutation were reduced, remarkably. Western Blot analysis revealed reduced protein expression by the mutation. Kir5.1 subunits display selective heteromultimerization with Kir4.1 constituting channels with unique kinetics. The effect of the mutation on Kir4.1/5.1 channel activity was twofold: a reduction in current amplitudes and an increase in the pH-dependent inhibition. We thus report a novel loss-of-function mutation in Kir4.1 found in a patient with a coexisting mutation in SLACK channels that results in a fatal disease. NEW & NOTEWORTHY We present and characterize a novel mutation in KCNJ10. Unlike previously reported EAST/SeSAME patients, our patient was heterozygous, and contrary to previous studies, mimicking the heterozygous state by coexpression resulted in loss of channel function. We report in the same patient co-occurrence of a KCNT1 mutation resulting in a more severe phenotype. This study provides new insights into the phenotypic spectrum and to the genotype-phenotype correlations associated with EAST/SeSAME and MMFSI. </jats:p
Cardiac Involvement in Nonketotic Hyperglycinemia
Nonketotic hyperglycinemia is an autosomal recessive disorder of glycine metabolism characterized by the accumulation of glycine in the serum and cerebrospinal fluid with elevated cerebrospinal fluid to serum glycine ratio. The disease primarily affects the central nervous system, and has not been previously associated with myocardial involvement. In this article, the authors report an infant with nonketotic hyperglycinemia, who was found to have progressive left ventricular hypertrophy and dysfunction. His older sibling, who had a similar neurologic presentation, died of dilated cardiomyopathy as stated by the parents. The authors speculate that glycine may have a role in the development of cardiac dysfunction. The incidence of cardiac involvement may be under-diagnosed. They suggest the need for a cardiac evaluation in confirmed cases of nonketotic hyperglycinemia. </jats:p
Go and Heal Our Kinship System
Keynote Speaker:
Dr. Grace L. Dillon is an academic and author. She is an Anishinaabe professor in the indigenous nations studies program, in the school of gender, race, and nations, at Portland State University. Dr. Dillon is best known for coining the term indigenous futurism, which is a movement consisting of art, literature, and other forms of media which express indigenous perspectives of the past, present, and future in the context of science fiction and related sub-genres. Dr. Dillon is the editor of walking the clouds: an anthology of indigenous science fiction, which is the first anthology of indigenous science fiction short stories, published by the University of Arizona press in 2012.
Join us for our annual Solidarity Town Hall program, an anchor discussion as part of Arabic American National Museum’s theme for Fall 2021 – Spring 2022: Istiqbal al Mustaqbal (Welcoming the Future). This year, the Town Hall is themed Imagining Decolonized Futures, highlighting futurist and sci-fi narratives as we imagine a world without colonial concepts. The Town Hall will feature keynote speaker: Anishinaabe academic and author Grace Dillon; and panelists: British Palestinian fiction writer Selma Dabbagh, multidisciplinary Afrofuturist artist Bryce Detroit, Canadian and Anishinaabe filmmaker Lisa Jackson; with moderator Hina Baloch, leader of the Research & Analytics team at GM. This is a virtual event taking place via Zoom
In onda. Saggi su donne e radiodrammi in Inghilterra dagli anni Ottanta ad oggi
In onda includes four essays on radio plays written by English female authors Marina Warner, Eva Figes, Selma Dabbagh and Timberlake Wertenbaker. The book analyses both original works for the radio and adaptations of classics and modern classics. The author examines the affirmation of women's voices and family relationships and conflicts
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