1,721,026 research outputs found
Chemical Vapour Generation of Arsane in the presence of l-Cysteine. Mechanistic studies and their analytical feedback
Caratterizzazione chimica dell’espirato umano in pazienti affetti da diabete mediante gas cromatografia/spettrometria di massa
Advances in clinical application of breath analysis by gas chromatography/mass spectrometry
Development of an Analytical Procedure for the Quantification of Volatile Compounds in Human Breath
Caratterizzazione chimica dell'espirato umano in pazienti affetti da diabete mediante GC/MS
Uric acid is the major determinant of absorbance in spent dialysate allowing spectrophotometric evaluation of dialysis dose
Background: Ultraviolet (UV) absorbance of spent dialysate has been proposed as a method for monitoring hemodialysis efficiency. The contribution of the various uremic toxins to UV absorption needs clarifying.
Methods: Urea, creatinine and uric acid were measured in blood and dialysate before and during dialysis in 22 maintenance hemodialysis patients. Absorbance was measured in dialysate.
Results: HPLC analyses of dialysate revealed uric acid as predominant peak. Spent dialysate absorbance decreased, during dialysis, similarly to serum and dialysate urea, creatinine and uric acid. Dialysate urea strictly correlated with absorbance, though urea did not contribute to absorbance, which was determined mostly by uric acid. Uric acid and urea removals were very similar. The spectrophotometric Kt/V correlated with sp Kt/V urea, with slight but significant differences between the two measurements.
Conclusions: The UV absorbance is determined mostly by uric acid. Absorbance measurements seem suitable in monitoring dialysis efficiency
A purge and trap method for the analysis of volatile organic compounds in human oral fluid
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