641 research outputs found

    The Brain-Dead Organ Donor

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    Addressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature. This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, and ethical aspects of brain death. That is followed by two chapters on the pathophysiology of brain death as investigated in small and large animal models. This includes a review of the many hormonal changes, including the neuroendocrine- adrenergic ‘storm’, that takes place during and following the induction of brain death, and how they impact metabolism. The next section of the book reviews various effects of brain death, namely its impact on thyroid function, the inflammatory response that develops, and those relating to innate immunity. The chapters relating to assessment and management of potential organ donors will be of interest to a very large group of transplant surgeons and physicians as well as critical care and neurocritical care physicians and nurses. Neurologists, endocrinologists, neurosurgeons, and pathologists will also be interested, especially in the more basic science sections on various aspects of brain-death and hormonal therapy. Organ procurement organizations and transplant coordinators worldwide will also be interested in this title. Other chapters will be of interest to medical historians, medico-legal experts, and ethicists.CONTENIDO: Introduction, Dimitri Novitzky, David K. C. Cooper, Pages 1-6 -- Historical Aspects of the Diagnosis of Death, Félix Bacigalupo, Daniela A. Huerta Fernández, Pages 7-11 -- The Determination of Brain Death, Curtis M. Keller, Boris Chulpayev, Michael Hoffmann, Pages 13-19 -- Legal Aspects of Brain Death and Organ Donorship, Ricky T. Munoz, Mark D. Fox, Pages 21-35 -- Ethical Issues in Organ Donation from Brain-Dead Donors, Mark D. Fox, Ricky T. Munoz, Pages 37-53 -- Pathophysiology of Brain Death in Small Animal Models, Bernhard Floerchinger, Nicholas L. Tilney, Stefan G. Tullius, Pages 55-64 -- Pathophysiology of Brain Death and Effects of Hormonal Therapy in Large Animal Models, Dimitri Novitzky, Winston N. Wicomb, David K. C. Cooper, Pages 65-90 -- The Efficacy of Thyroid Hormone Therapy in Brain-Dead Heart Donors: A Review of Thyroid Function in Health and Disease, Lawrence E. Shapiro, Tatiana Baron, Pages 91-105 -- The Inflammatory Response to Brain Death, Anne Barklin, Christine Lodberg Hvas, Else Toennesen, Pages 107-119 -- The Influence of Brain Death and Intensive Care Management on Donor Organs: Assessment of Inflammatory Markers, Wayel Jassem, Susan V. Fuggle, Pages 121-129 -- Brain Death-Induced Inflammation: Possible Role of the Cholinergic Anti-inflammatory Pathway, Simone Hoeger, Benito A. Yard, Pages 131-138 -- Innate Immunity and Injury During Brain Death: Opportunities for Intervention, Marc A. Seelen, Henri G. D. Leuvenink, Rutger J. Ploeg, Pages 139-145 -- Selection of the Brain-Dead Potential Organ Donor, Kadiyala V. Ravindra, Keri E. Lunsford, Paul C. Kuo, Pages 147-154 -- Infectious Disease Aspects of the Brain-Dead Potential Organ Donor, Nicole M. Theodoropoulos, Michael G. Ison, Pages 155-176 -- Malignancy in the Brain-Dead Organ Donor, Michael A. Nalesnik, Ron Shapiro, Michael G. Ison, Pages 177-189 -- Early Clinical Experience of Hormonal Therapy in the Brain-Dead Potential Organ Donor, Dimitri Novitzky, Burcin Ekser, David K. C. Cooper, Pages 191-207 -- Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in the USA, Demetrios Demetriades, Lydia Lam, Pages 209-216 -- Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in Europe, Gabriel J. Echeverri, Bruno G. Gridelli, Pages 217-235 -- Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in Australia, Peter S. Macdonald, Anders E. M. Aneman, Deepak Bhonagiri, Daryl A. Jones, Gerry O’Callaghan, Helen I. Opdam et al., Pages 237-249 -- Management of the Brain-Dead Organ Donor: Perspectives of the Transplant Coordinator, Nicole T. Farina, David K. C. Cooper, Pages 251-261 -- Surgical Aspects of Thoracic and Abdominal Organ Procurement from Brain-Dead Donors, Michael J. Anstadt, Paul C. Kuo, Kadiyala V. Ravindra, Pages 263-281 -- Impact of Brain Death on Storage of the Heart, Winston N. Wicomb, David K. C. Cooper, Pages 283-288 -- Impact of Brain Death on Abdominal Organs and Allograft Preservation Strategies, Coney Bae, Anthony Watkins, Scot D. Henry, James V. Guarrera, Pages 289-298 -- Functional Repair of Brain Death-Induced Injury, Henri G. D. Leuvenink, Marc A. Seelen, Rutger J. Ploeg, Pages 299-310 -- Functional Repair of Brain Death-Injured Donor Lungs, Jonathan C. Yeung, Marcelo Cypel, Shaf Keshavjee, Pages 311-320 -- Thyroid Hormone Therapy to the Recipient of a Heart from a Brain-Dead Donor, Dimitri Novitzky, David K. C. Cooper, Pages 321-331 -- Current and Potential Future Trends in the Management of the Brain-Dead Organ Donor, Octavio E. Pajaro, James K. Kirklin, Pages 333-341 -- Maximizing Utilization of the Potential Deceased Donor: The Challenge Continues,Eliezer Katz,Pages 343-35

    Saint Dimitri of Rostov and Dostoevsky

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    Academic literature until now has ignored the possibility of seeing the roots of Dostoevsky’s idea of a God-bearing people in the Saint Dimitri of Rostov’s conception of the passion bearer. But, on the contrary, obvious parallels between the two permit the author to speak of a deliberate coincidence. On the other hand, the two are divided in their conceptions of the reasons for human sufferin

    Die Herkunft des byzantinischen Familiennamens Λάσκαρις

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    In this article, the author suggests a new etymology for the name Laskaris, born by a family that gave Byzantium one of its imperial dynasties. Older hypotheses are examined, especially the generally accepted one according to which Laskaris is a name of Persian origin meaning "warrior." The author suggests Lascaris rather comes from a Arabic word defining a physical feature: "blonde" or "red-haired.REB 62 2004 p. 269-273 Dimitri Theodorides, Die Herkunft des Byzantinischen Familiennamens Αάσκαρις. — Cet article propose une nouvelle étymologie du nom Lascaris, porté par une famille qui donna une dynastie à Byzance. L'auteur reprend les hypothèses proposées, notamment celle qui est généralement admise et qui ferait de Lascaris un nom d'origine perse, signifiant le « guerrier ». L'auteur propose plutôt d'y voir un mot arabe caractérisant un trait physique : le « blond » ou le « roux ».Theodoridis Dimitri. Die Herkunft des byzantinischen Familiennamens Λάσκαρις. In: Revue des études byzantines, tome 62, 2004. pp. 269-273

    Take me to church

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    This thesis is a narrative of masculinity and Latinx identity. More specifically, multiple generations of Puerto Ricanness.M.F.A.Includes bibliographical referencesby Dimitri Reye

    Book Launch | Dimitri Van Den Meerssche's The World Bank's Lawyers

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    On Wednesday 16 November, the ESIL Interest Groups on History of Intentional Law and International Organisations and Völkerrechtsblog, hosted a book launch for The World Bank’s Lawyers by Dr. Dimitri van den Meerssche (Queen Mary University London).In addition to hearing from the author, discussants included Negar Mansouri (Graduate Institute of International and Development Studies), Dr Gail Lythgoe (University of Manchester), Dr. Tommaso Soave (Central European University) and Dr. Ahmed Memon (Cardiff School of Law and Politics). Florenz Volkaert (Ghent University) moderated.<br/

    Book Launch | Dimitri Van Den Meerssche's The World Bank's Lawyers

    No full text
    On Wednesday 16 November, the ESIL Interest Groups on History of Intentional Law and International Organisations and Völkerrechtsblog, hosted a book launch for The World Bank’s Lawyers by Dr. Dimitri van den Meerssche (Queen Mary University London).In addition to hearing from the author, discussants included Negar Mansouri (Graduate Institute of International and Development Studies), Dr Gail Lythgoe (University of Manchester), Dr. Tommaso Soave (Central European University) and Dr. Ahmed Memon (Cardiff School of Law and Politics). Florenz Volkaert (Ghent University) moderated.<br/

    Book Launch | Dimitri Van Den Meerssche's The World Bank's Lawyers

    No full text
    On Wednesday 16 November, the ESIL Interest Groups on History of Intentional Law and International Organisations and Völkerrechtsblog, hosted a book launch for The World Bank’s Lawyers by Dr. Dimitri van den Meerssche (Queen Mary University London).In addition to hearing from the author, discussants included Negar Mansouri (Graduate Institute of International and Development Studies), Dr Gail Lythgoe (University of Manchester), Dr. Tommaso Soave (Central European University) and Dr. Ahmed Memon (Cardiff School of Law and Politics). Florenz Volkaert (Ghent University) moderated.<br/

    Unemployment insurance in Algeria : implications for a labor market in transition

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    To predict how Algeria's unemployment crisis will evolve, the author evaluates the Algerian unemployment insurance system's ability to finance itself, to affect employment decisions, and promote enterprise restructuring. The main conclusion is that industrial restructuring has serious and persistent implications for the labor market. In an environment where many equilibria are possible, there is a real danger of reaching a high unemployment equilibrium. The big-bang experience of structural adjustment in Central and Eastern Europe transition economies resulted in large-scale unemployment. Despite considerable restructuring progress, structural rigidities still exist in the labor market, and long-term unemployment has persisted. One advantage of the big-bang approach is adjustment speed, but the resulting unemployment may be too costly for Algeria's economy, especially if it persists. A more modern mixed bang approach would incorporate active employment measures to mitigate entrenched unemployment. The policies will maintain or enhance human capital through work, so idle workers don't lose their skills. Flex-time arrangements would help workers maintain an attachment to the labor force. However minor, such work would help workers avoid the traps of long-term unemployment. Two striking conclusions emerge from the Central and Eastern European experience: a) unemployment is not essential to enterprise restructuring and labor market adjustment;and b) growing long-term unemployment is self-fulfilling and results in higher and persistence unemployment. Although active employment measures are costly and have relatively low rates of return in the short run, they can be marginally effective as part of a long-term strategy.Health Economics&Finance,Labor Policies,Environmental Economics&Policies,Labor Markets,Economic Theory&Research,Environmental Economics&Policies,Labor Markets,Economic Theory&Research,Health Economics&Finance,Banks&Banking Reform

    Emerging properties of the citations network

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    Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2024, Tutor: Dimitri MarinelliThis essay presents an analysis of the American Physical Society (APS) dataset, comprising metadata and citations of APS articles. We focus on network structures behind the dataset. We build three different networks: citation network, author citation networks, and co-author network. We compute key network metrics such as degree distribution, clustering coefficients, and centrality measures. We expect the degree distribution of the different networks to follow a power-law distribution. Through simulations, we compare the citation network structure to randomly generated directed graphs built by the configuration model with the same degree distribution, obtaining substantially different structural configurations. The in-degree distribution of the citation network exhibited scale-free properties, compatible with the preferential attachment network development. This study provides a comprehensive understanding of the APS citation network and emphasizes the importance of temporal and preferential attachment mechanisms in shaping real-world network

    Uncertainty and propagation analysis on DIMITRI

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    DIMITRI is a tool that has been developed for monitoring the radiometric performance of optical instruments onboard Earth observation satellites. It includes a reflectance model through which a calibration coefficient is computed which is used for performance monitoring. In this thesis, the uncertainty that is associated with this coefficient is researched and a classification in random and systematic uncertainty components is attempted. Throughout this research it became clear that such a classification is somewhat ambiguous and can be misleading because systematic uncertainties are not always constant. In order to identify such uncertainties, the entire modelling / measurement process with respect to the input variables of the reflectance model, and the algorithm of the reflectance model itself, have been researched for potential uncertainty sources. What became clear is that input variable uncertainties are of both nature; random and systematic. In addition, a sensitivity analysis has been conducted to assess how the calibration coefficient depends on changes in the input variables. Out of these, the Chlorophyll variable causes the highest deviations due to the large uncertainties associated with this parameter. This research has been able to identify uncertainty sources but has not been able to assign any value to those sources. Any subsequent research could use the identified uncertainty sources described here and attempt to quantify their value to yield a total uncertainty that can be associated to the calibration coefficient. This will increase the usability of this performance monitoring coefficient which means that the user will obtain more information regarding the accuracy of the performance degradation of the optical instrument onboard Earth observation satellites.Aerospace Engineering | Space Fligh
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