186,298 research outputs found

    Distributed Minimum Time Servicing for a Team of Dubins Vehicles

    No full text
    In this paper we study the following problem for a team of Dubins vehicles, i.e. nonholonomic vehicles moving at constant longitudinal speed along planar paths with bounded curvature. Given the initial configurations of the vehicles, find the point in the plane that minimizes the time to be reached by all vehicles. We call it "minimum-time servicing problem". We show that this problem can be approximated by an abstract linear program, namely a generalized version of linear programming, that can be solved in a distributed way over a network. We provide a control and communication law for a wireless network of Dubins vehicles to compute and reach the "minimum-time servicing point" while maintaining the network connected

    Unveiling guanosine hydrogel properties: Mid and Far infrared spectroscopic insights

    No full text
    Guanosine possesses the intrinsic ability to self-assemble in aqueous environments, giving rise to supramolecular architectures ranging from G-quartets to G-quadruplexes. These, in turn, can undergo cross-linking or entanglement, forming a molecular hydrogel with promising biotechnological properties. Infrared spectroscopy can successfully unravel the structural and dynamic properties of these supramolecular assemblies, revealing spectral features indicative of quartets, octamers, and quadruplex formation, and is used to monitor the formation of G-hydrogels

    Sedation with midazolam for electrical cardioversion

    No full text
    Background: Electrical cardioversion (ECV) usually requires the assistance of the anesthesiology team. To avoid this dependence, previous studies have considered the use of sedation with benzodiazepines administered by cardiologists. We describe our experience with intravenous Midazolam during cardioversion. Methods:We performed 280 ECV in 202 patients sedated with intravenous Midazolam, without anesthesiology supervision. In scheduled cardioversions, we tested two protocols of Midazolam administration: a bolus of 3 mg, followed by 2 mg each minute until necessary, and a loading dose of 0.09–0.1 mg/kg. In cardioversions performed during electrophysiology studies or defibrillator implant, Midazolam was administered by small repeated doses during the entire procedure. Results: Midazolam was effective to obtain adequate sedation in 99% of cases. All patients had amnesia with regards of the cardioversion. A loading dose of Midazolam allowed a shortening of the procedural time without serious adverse events. Intubation or the assistance of an Anesthetist was never necessary. Conclusion: Sedation with Midazolam for ECV is effective and well tolerated, with some cautions discussed. A loading dose of Midazolam is well tolerated and further reduces the procedural time

    First ATR-FTIR Characterization of Black, Green and White Teas (Camellia sinensis) from European Tea Gardens: A PCA Analysis to Differentiate Leaves from the In-Cup Infusion

    No full text
    ATR-FTIR (Attenuated Total Reflectance Fourier Transform InfraRed) spectroscopy, combined with chemometric, represents a rapid and reliable approach to obtain information about the macromolecular composition of food and plant materials. With a single measurement, the chemical fingerprint of the analyzed sample is rapidly obtained. Hence, this technique was used for investigating 13 differently processed tea leaves (green, black and white) all grown and processed in European tea gardens, and their vacuum-dried tea brews, prepared using both hot and cold water, to observe how the components differ from tea leaf to the in-cup infusion. Spectra were collected in the 1800–600 cm−1 region and were submitted to Principal Component Analysis (PCA). The comparison of the spectral profiles of leaves and hot and cold infusions of tea from the same country, emphasizes how they differ in relation to the different spectral regions. Differences were also noted among the different countries. Furthermore, the changes observed (e.g., at ~1340 cm−1) due to catechin content, confirm the antioxidant properties of these teas. Overall, this experimental approach could be relevant for rapid analysis of various tea types and could pave the way for the industrial discrimination of teas and of their health properties without the need of time-consuming, lab chemical assays

    Paroxysmal atrial fibrillation ablation with the mutlipolar mapping and ablation catheter

    No full text
    Pulmonary veins (PVs) ablation is a valid treatment option for atrial fibrillation. The standard approach for PVs isolation usually requires two catheters or an electroanatomical reconstruction of the left atrium. We describe our initial experience with a single device for mapping and ablating in a patient referred to our center for the relapsing of atrial fibrillation 3 years after a previous ablation procedure. The newly available catheter MESH was safe and effective to quickly isolate two reconnected. Introduction Ablation within or around the pulmonary veins (PVs) is a valid treatment option for atrial fibrillation. Usually PVs isolation requires the combined use of a multielectrode catheter for mapping together with an ablation catheter. Alternatively a point-by-point mapping and ablation can be achieved using a three-dimensional nonfluoroscopic system.1–7 We describe the case of a patient with recurrent paroxysmal atrial fibrillation subjected to PVs ablation by using a newly available device that allows to map and ablate simultaneously with the same catheter
    corecore