1,721,412 research outputs found
Application possibility of the tDCS in the diagnostics and therapy of neuropsychiatric disorders
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Noninvasive brain stimulation protocols in the treatment of epilepsy: Current state and perspectives
No full textIn epileptic seizures, there is an enhanced probability of neuronal networks to fire synchronously at high frequency, initiated by a paroxysmal depolarisation shift. Reducing neuronal excitability is a common target of anti-epileptic therapies. Beyond or in addition to pharmacological interventions, excitability-reducing brain stimulation is pursued as an alternative therapeutic approach. Hereby, non-invasive brain stimulation tools, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), have gained increased interest as efficient tools to modulate cortical excitability and activity. In animal models, stimulation-induced cortical excitability diminution has been shown to be suited to reduce seizures. Clinical studies conducted to date, however, have shown mixed results. Reasons for this, as well as possible optimization strategies that might lead to more efficient future stimulation protocols, will be discussed
Impairment of motor cortex plasticity in Parkinson's disease, as revealed by theta-burst-transcranial magnetic stimulation and transcranial random noise stimulation
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Vascular safety of brain plasticity induction via transcranial direct currents
No full textExperience alters the strength of neuronal connections as a fundamental feature of brain physiology. This process, termed neuroplasticity, appears crucially involved in cognitive processes such as learning, memory formation, and adaptive behavior. Neuroplasticity is increasingly implicated in not only a number of neurologic diseases, but also in restitution after brain injury. Noninvasive brain stimulation can induce and modulate neuroplasticity in humans.(1) In accordance with the functional relevance of neuroplasticity, noninvasive brain stimulation not only modulates psychological processes and behavior in healthy humans, but also reduces symptoms, and improves rehabilitation, in patients with neurologic diseases, including stroke.(2-4</SUP
Transcranial direct current stimulation - update 2011
No full textNon-invasive brain stimulation with weak direct currents (transcranial direct current stimulation (tDCS)) has emerged as one of the major tools to induce neuroplastic cortical excitability alterations in humans since its (re-) introduction to the arsenal of plasticity-inducing brain stimulation tools. In this review, we gather newly emerged knowledge about the effect of tDCS on brain function in both, basic and applied research. This overview will deliver an update of the last two years of research, because especially during this time numerous important studies were published covering the above-mentioned fields
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