132 research outputs found
Dataset of Chemiluminescent Chemosensor-Based Assay
No full text<p>This dataset allows to analyze the results in the study of the chemiluminescent chemosensor-based assay by Nilima Manoj Kumar, Pierre Picchetti, Changming Hu, Laura M. Grimm, and Frank Biedermann.</p>
<p>When using the data, please cite the corresponding paper. </p>
Unimolecular Cucurbit[7]uril‐Based Indicator Displacement Assay with Dual Signal‐Readout for the Detection of Drugs
No full textPoint-of-care diagnostics relies on optical and electrochemical sensors to develop devices that are both compact and cost-effective. Therefore, the search for new design principles for chemosensors that enable multiple signal outputs is a particularly interesting concept. In this work, we present an unimolecular chemosensor based on cucurbit[7]uril that combines two signal readouts - namely fluorescent and electrochemical signals - in a single chemosensor design. This is achieved by utilizing the tunable fluorescence and the electrochemical properties of the reporter molecule, which depend on whether or not it is engulfed by the cucurbit[7]uril cavity in the absence or presence of the analyte. By setting up an assay using the dual readout chemosensor, illicit drug formulations containing pancuronium bromide or nicotine can be detected at low micromolar concentrations (0–100 μM). This assay is compatible with standard fluorescence plate readers and electrochemical devices, including commercially available screen-printed electrodes. Overall, the chemosensor presented in this study represents a significant advance in the development of cucurbit[7]uril chemosensors, characterized by multimodal detection capabilities. It uniquely combines traditional optical and electrochemical detection methods in a single molecular design
RECTIFIED DIFFERENTIAL CRYPTANALYSIS OF 16 ROUND PRESENT
No full textRECTIFIED DIFFERENTIAL CRYPTANALYSIS OF 16 ROUND PRESENT
Manoj Kumar , Pratibha Yadav and Meena Kumari
SAG, DRDO, Metcalfe House, Delhi-110054, India
ABSTRACT
In this paper, we have suggested rectifications in differential cryptanalysis of ultra-lightweight block cipher PRESENT reduced to 16 rounds. We have shown that proposed differential attack by Wang [3] on 16 round PRESENT can recover at the most 30 subkey bits, although the author has claimed to recover 32 bits of subkey for last two rounds. We have also computed data complexity and success probability for recovering 30 subkey bits accordingly by the differential attack on 16 round PRESENT.
KEYWORDS
Lightweight block cipher, differential cryptanalysis, PRESEN
Book Review: \u27Transit Talks: Living through Difficult Times\u27
No full textName of Book: Transit Talks: Living through Difficult Times
Author: Manoj Kumar Jha
Published: 2013
Published By: AlterNotes Press, New Delhi, India
Paper or Hardcover: ISBN: Paperback. ISBN: 978-8190892353
Number of Pages: xix + 316
 
Post-Reform Development in Asia: Essays for Amiya Kumar Bagchi
No full textThis festschrift volume for professor Amiya Kumar Bagchi dwells on issues often raised in the development debate whether neo-liberal reforms in developing nations have raised inequality and poverty, food insecurity, hindered empowerment of women, aggravated agrarian distress, reallocated resources for private profitability and facilitated the rise of multi-national oligopoly according inferior status to the domestic industries in the host countries most of the issues have been examined on the basis of empirical data drawn from China, India and Bangladesh essays on china concentrate on post-reform issues of inequality across regions and rural-urban locations and its failure to achieve targets of human development while experiencing rapid economic growth discussions on changes in policy environment since the early days of the people\u27s republic of china also constitute the basic themes of the essays food insecurity, growth-poverty-employment relationship, gender discrimination in the labour market and agrarian distress caused by withdrawal of state support to small farmers growing commercial crops and revision of priority sector lending policy at the cost of small farmers and entrepreneurs are the major themes of essays written in the Indian context of post-reform development in an essay on Bangladesh the poverty issues has been revisited in the context of child work agrarian issues have also been raised in an essay where the author proposes an alternative peasant social construction for the dual affirmation of land rights of the state and of the peasant family in the last two essays authors look far beyond the mainstream tradition to develop an analytical framework for understanding issues relating to the recent rise of multi-national firms and the phenomenal growth of India\u27s software technology. -- Provided by publisherhttps://scholarworks.uni.edu/facbook/1150/thumbnail.jp
D-Penicillamine for preventing retinopathy of prematurity in preterm infants
No full textBackground The rate of retinopathy of prematurity (ROP) in moderately premature infants has decreased dramatically with improved care in the neonatal intensive care unit. A low rate of this disorder was unexpectedly observed among infants treated with intravenous D-penicillamine to prevent hyperbilirubinaemia. This observation led to the investigation of its use, both enterally as well as intravenously, to prevent ROP. Objectives To determine the effect of prophylactic administration of D-penicillamine on the incidence of acute ROP or severe ROP and other morbidities in preterm infants. Search methods We used the Cochrane Neonatal Review Group search strategy. Two review authors independently searched multiple electronic databases, previous reviews including cross references, abstracts, conference/symposia proceedings, and expert informants. We updated the search on November 27, 2012. Selection criteria We included randomised or quasi-randomised controlled trials if they administered D-penicillamine and compared it with no treatment or placebo to premature infants and reported on the outcome of ROP. Data collection and analysis We used the criteria and standard methods of the Cochrane Neonatal Review Group to assess the methodological quality of the included trials. One review author examined trials for validity. A second review author checked validity and they reached consensus on the final data before entry into this review. We used the standards of the Neonatal Cochrane Review Group to analyse data. Main results Three randomised trials met the inclusion criteria. The meta-analysis showed no significant differences in the risk of any stage ROP (typical risk ratio (RR) 0.32, 95% confidence interval (CI) 0.03 to 3.70), severe ROP (typical RR 0.38, 95% CI 0.03 to 4.26) or death (typical RR 0.95, 95% CI 0.68 to 1.32) in all treated infants. When the subgroup of infants under 1500 g birth weight was examined, the results were similar. No side effects were reported, and follow-up at one year revealed no significant differences in spasticity or developmental delay. Authors' conclusions Administration of prophylactic D-penicillamine in preterm infants does not prevent acute or severe ROP, death or neurodevelopmental delay. D-penicillamine cannot be recommended for the prevention of ROP based on the available evidence
13C nuclear magnetic resonance spectroscopy (13C NMR) ()
No full textdataset for 13C nuclear magnetic resonance spectroscopy (13C NMR)
13C NMR (CDCl3, 126 MHz, ppm) δ = 155.34, 143.06, 137.17, 131.95, 129.16, 122.11, 116.02, 114.41, 57.78 (2C), 39.22, 39.08, 37.19, 32.23, 30.23, 28.32 (3C)
electrospray ionisation mass spectrometry (ESMS) (tert-butyl-[3-[dimethoxyphosphoryl(methoxy)methyl]phenoxy]-dimethylsilane)
No full textdataset for electrospray ionisation mass spectrometry (ESMS)
ESI-MS m/z [M+Na]+calcd for C16H29O5PSiNa 383.1419; found 383.1498
1H nuclear magnetic resonance spectroscopy (1H NMR) ()
No full textdataset for 1H nuclear magnetic resonance spectroscopy (1H NMR)
1H NMR (CDCl3, 500 MHz, ppm) δ = 7.23-7.20 (m, 1H), 6.89 (d, J = 10 Hz, 1H), 6.81 (s, 1H), 6.77–6.75 (m, 1H), 4.87 (s,1H), 3.30 (s, 1H), 3.24 (s, 3H), 2.65 (s, 1H), 1.97–1.79 (m, 12H).
Fourier transform infrared spectroscopy (FTIR) (tert-butyl-[3-[dimethoxyphosphoryl(methoxy)methyl]phenoxy]-dimethylsilane)
No full textdataset for Fourier transform infrared spectroscopy (FTIR)
IR (ATR, ṽ) = 2955 (m), 2930 (m), 2857 (w), 1601 (w), 1482 (w), 1473 (w), 1273 (s), 1253 (s), 1055 (s), 1028 (vs), 1003 (m), 984 (m), 865 (m), 827 (s), 815 (m), 780 (s), 764 (w) cm–1
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