285 research outputs found

    Einfluss der intraaortalen Ballonpumpe auf die Entwicklung der systemischen Inflammation und die Mortalität bei Patienten im kardiogenen Schock nach akutem Myokardinfarkt

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    Der infarktbedingte kardiogene Schock ist mit einer hohen Mortalität verbunden. Der Einsatz der intraaortalen Ballonpumpe (IABP) bewirkt eine Verbesserung der Energie-bilanz des Herzens. Ziel dieser Arbeit im Rahmen der prospektiven, monozentrischen IABP-Schock-Studie ist es, anhand serieller Messungen von IL-6, IL-7, IL-8, IL-10, TNF-α, IFN-γ, G-CSF, MCP-1 und MIP-1β die prognostische Wertigkeit dieser Zytokine bezüglich Überleben und den Einfluss der IABP auf die Entwicklung der systemischen Inflammationsreaktion zu untersuchen. Vierzig Patienten mit der Diagnose eines kar-diogenen Schocks nach akutem Myokardinfarkt wurden in eine Gruppe mit IABP (n=19) und eine Kontrollgruppe (n=21) randomisiert. Zytokine sind bezüglich der Morta-lität prognostisch relevant. Die maximalen Zytokinspiegel sind dabei den initialen über-legen. IFN-γ hat die beste prognostische Genauigkeit. Es konnte kein positiver oder negativer Einfluss der IABP auf die systemische Entzündungsreaktion nachgewiesen werden.The infarct-related cardiogenic shock is associated with a high mortality. The use of the intra-aortic balloon pump (IABP) is effective for improving the energy balance of the heart. The aim of this study as a part of the prospective, monocentric IABP-Shock-Study was to determine the prognostic value of IL-6, IL-7, IL-8, IL-10, TNF-α, IFN-γ, G-CSF, MCP-1 and MIP-1β regarding mortality and to investigate the influence of the IABP on the development of the systemic inflammation on the basis of serial measurements of these cytokines. Forty patients with a diagnosis of cardiogenic shock after acute myocardial infarction were randomized into a group with IABP-treatment (n=19) and a control group (n=21). Cytokines are prognostically relevant for mortality. The maximum cytokine levels are in this regard superior to the initial levels. IFN-γ has the best prognostic accuracy. There was no evidence of a positive or negative effect of the IABP on the systemic inflammatory response.von Nikolas Arne Wegene

    Comparison of Ground and Laser Machined Wiper Geometry on Carbide Inserts for High Performance Finishing

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    AbstractCutting tool development is still driven by trial and error and therefore requires various prototypes and modifications. The normal manufacturing process for carbide cutting inserts includes die production, pressing, sintering, grinding and coating. A laser can provide an easy and economical way to make modifications and prototypes out of pressed inserts. The paper compares a normal pressed and ground insert with the same geometry using various laser manufacturing options. The insert features a wiper geometry for high feed per revolution and a chip breaker. As performance criteria the cutting forces and the machined surface quality were measured and analysed. It was found that the cutting edge and surface quality of the insert depends on the laser strategy and thus influences the cutting force and the workpiece quality. No difference was discovered comparing ground and laser machined inserts showing the potential for prototyping

    A Grammar of Savosavo

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    Wegener C. A Grammar of Savosavo. Mouton Grammar Library. Vol 61. Berlin, New York: Mouton de Gruyter; 2012.This is the first comprehensive description of Savosavo, a non-Austronesian (Papuan) language spoken by approximately 2,500 speakers on Savo Island, Solomon Islands. Based on primary field data recorded by the author, it provides an overview of all levels of grammar. In addition, a full chapter is dedicated to nominalization of verbs by means of one particular suffix, which occur in a number of constructions ranging from lexical to syntactic nominalization. The appendix provides glossed example texts and a list of lexemes

    Regional aspects of decision-making support for rural development in Poland

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    Measures for rural development should be adapted to the specific regional conditions and national programs should allow for different regional priorities. However, decision-making for policy measures often takes place under special conditions with many concerned actors, unstructured decision problems and time pressure. These conditions, decision-makers in administrations and institutions are faced with, make the formation of policy-measures for rural development a complex matter. Thus, there is the question arising how decision-makers can be supported in setting priorities for allocating budgets for policy measures among regions. Recently, multi criteria decision-making approaches are discussed to tackle these kinds of decision problems. We show exemplarily for the Polish program of rural development, how decision-making could be supported using a multi-objective programming approach. Different preferences of actors can be considered explicitly by visualizing “trade-offs” and an interactive use of the approach. For example, a political "equity" objective is implemented as a constraint in the programming approach, restricting the budget differences between regions to a defined level. By a parameterization of the bound for budget differences, the "trade-off" between three objectives is displayed and evaluated. Using the exemplary programming approach, it is shown that the objective values of the two main objectives of the PROW decline, when the budget differences between regions are restricted for pursuing a political "equity" objective.Regional Budgeting, Interactive Decision-making support, Multi-objective Programming (MOP), Community/Rural/Urban Development,

    What should I do?: Deriving norms from actions,values and context

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    Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Interactive Intelligenc

    Modelling the Social Environment: Towards Socially Adaptive Electronic Partners

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    Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Interactive Intelligenc

    El Tlacuache Núm. 501 (2012). 501 Año 13 (2012) enero. El Tlacuache

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    Wegener, la tectónica de placas y la evolución humana por Eduardo Corona Martínez. -La teoría de la deriva continental de Alfred Lothar Wegener: 100 años por Carlos Pérez Malváez, Alfredo Bueno Hernández, Guadalupe Bribiesca Escutia, Fabiola Juárez Barrer

    Les Delassements D\u27Eros : sexuality and gender identity in Gerda Wegener\u27s erotic aquarelles

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    This thesis examines the representations of sexuality and gender identity in Gerda Wegener\u27s erotic illustrations in Les Delassements D\u27Eros: Douze Sonnets Lascifs ( The Amusements of Eros: Twelve Lustful Sonnets ). In 1925, Gerda Wegener, a Danish artist, collaborated with Louis Perceau, a French poet and connoisseur of erotica, to illustrate a book of erotic poetry known as Les Delassements D\u27Eros. Her illustrations consist of twelve watercolors, called aquarelles, with female-female sex as well as other sexual mythological and carnival imagery. For many years, both the author and the artist were unknown because the book was published anonymously due to its erotic content. The popular female model in her artworks was her husband, Einar, who in 1930 underwent the first successful sex reassignment surgery to identify as a woman. Through the inclusion of Einar as her female model in her illustrations as well as female-female sex, Gerda pushes and blurs the boundaries of gender and sexuality during the early twentieth century in Paris. Her works explore the fashioning of identity and the collapse of cultural barriers, and express a passion for women and beauty, all of which are still relevant today

    Optimal Ordered Binary Decision Diagrams for Tree-like Circuits

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    Many Boolean functions have short representations by OBDDs (ordered binary decision diagrams), if appropriate variable orderings are used. For tree-like circuits which may contain EXOR-gates it is proved that some depth first traversal leads to an optimal variable ordering. Moreover, an optimal variable ordering and the resulting OBDD can be computed in time linear in the number of variables and the size of the OBDD, respectively. Upper and lower bounds on the OBDD size of the functions representable by tree-like circuits are derived. For, e. g., 1024 inputs we show that all tree-like circuits have OBDDs of size at 5349 and we give an example of a tree-like circuit requiring an OBDD of size 5152. Index Terms Ordered binary decision diagram, efficient algorithms, Boolean function, variable ordering, tree-like circuit. Email Addresses sauerhof/[email protected] [email protected] Acknowledgements The first and second author have been support..
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