17 research outputs found
Rousseau e a radicalidade democrática: um debate com a interpretação de Kevin Inston
No full textRousseau's association to the philosophical sources of democracy is not free of discussion. The author himself preferred the qualification of “republican” instead of “democrat”, and in the Social Contract he pointed out serious difficulties for the existence of democracy as a form of government, even though his theses on popular sovereignty reverberate principles typically linked to democratic constitutions. In view of this, Kevin Inston questioned that contemporary radical democrats have neglected the contribution of the Genevan philosopher, and for this reason he sought to show how much it remains relevant to face the political challenges of our times. However, to what extent are Inston’s efforts to reconcile Rousseau's political theory with contemporary democracy sustainable? Has not the commentator underestimated or ignored crucial elements that make such convergence problematic? The purpose of this paper is to try to provide some answers to such questions.A associação de Rousseau às fontes filosóficas da democracia não constitui algo livre de discussões. O próprio autor preferia a qualificação de “republicano” em vez de “democrata”, e no Contrato Social apontou sérias dificuldades para a existência da democracia como uma forma de governo, ainda que suas teses sobre a soberania popular reverberem princípios tipicamente ligados às constituições democráticas. Diante disso, Kevin Inston questionou que os democratas radicais contemporâneos tenham negligenciado a contribuição do filósofo genebrino, e por isto buscou mostrar o quanto ela continua sendo relevante para enfrentar os desafios políticos da atualidade. Todavia, em que medida se sustentam os esforços de Inston para compatibilizar a teoria política rousseauniana com a democracia contemporânea? Não terá o comentador subestimado ou ignorado elementos cruciais que tornam tal convergência problemática? O objetivo deste artigo é tentar fornecer algumas respostas para tais perguntas
sj-pdf-2-jva-10.1177_11297298241236521 – Supplemental material for Quality assurance in surgical trials of arteriovenous grafts for haemodialysis: A systematic review, a narrative exploration and expert recommendations
No full textSupplemental material, sj-pdf-2-jva-10.1177_11297298241236521 for Quality assurance in surgical trials of arteriovenous grafts for haemodialysis: A systematic review, a narrative exploration and expert recommendations by David B Kingsmore, Ben Edgar, Emma Aitken, Francis Calder, Marco Franchin, Colin Geddes, Nick Inston, Andrew Jackson, Rob G Jones, Nikolaos Karydis, Ram Kasthuri, Gaspar Mestres, Georgios Papadakis, Rajesh Sivaprakasam, Mike Stephens, Karen Stevenson, Callum Stove, Lazslo Szabo, Peter C Thomson, Matteo Tozzi and Richard D White in The Journal of Vascular Access</p
sj-pdf-1-jva-10.1177_11297298241236521 – Supplemental material for Quality assurance in surgical trials of arteriovenous grafts for haemodialysis: A systematic review, a narrative exploration and expert recommendations
No full textSupplemental material, sj-pdf-1-jva-10.1177_11297298241236521 for Quality assurance in surgical trials of arteriovenous grafts for haemodialysis: A systematic review, a narrative exploration and expert recommendations by David B Kingsmore, Ben Edgar, Emma Aitken, Francis Calder, Marco Franchin, Colin Geddes, Nick Inston, Andrew Jackson, Rob G Jones, Nikolaos Karydis, Ram Kasthuri, Gaspar Mestres, Georgios Papadakis, Rajesh Sivaprakasam, Mike Stephens, Karen Stevenson, Callum Stove, Lazslo Szabo, Peter C Thomson, Matteo Tozzi and Richard D White in The Journal of Vascular Access</p
Quality assurance in surgical trials of arteriovenous grafts for haemodialysis: protocol for a systematic review
No full textIntroduction Decisions regarding the optimal vascular access for haemodialysis patients are becoming increasingly complex, and the provision of vascular access is open to variations in systems of care as well as surgical experience and practice. Two main surgical options are recognised: arteriovenous fistula and arteriovenous graft (AVG). All recommendations regarding AVG are based on a limited number of randomised controlled trials (RCTs). It is essential that when considering an RCT of a surgical procedure, an appropriate definition of quality assurance (QA) is made for both the new approach and the comparator, otherwise replication of results or implementation into clinical practice may differ from published results. The aim of this systematic review will be to assess the methodological quality of RCT involving AVG, and the QA measures implemented in delivering interventions in these trials.
Methods and analysis The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines will be followed. A systematic search will be performed of the MEDLINE, Embase and Cochrane databases to identify relevant literature. Studies will be selected by title and abstract review, followed by a full-text review using inclusion and exclusion criteria. Data collected will pertain to generic measures of QA, credentialing of investigators, procedural standardisation and performance monitoring. Trial methodology will be compared against a standardised template developed by a multinational, multispecialty review body with experience in vascular access. A narrative approach will be taken to synthesise and report data.
Ethics and dissemination Ethical approval is not required as it is a protocol for a systematic review. Findings will be disseminated through peer-reviewed publications and conference presentations, with the ultimate aim of providing recommendations for future RCT of AVG design.Full Tex
The brachiobasilic arteriovenous fistula: effect of patient variables.
No full textPurpose: The hemodialysis population is constantly expanding as patients on dialysis have increased longevity and the number of kidneys available for transplantation remains static (1). After radiocephalic and brachiocephalic fistulas have been exhausted the use of the autologous brachiobasilic fistula (BBAVF) should be considered prior to use of a synthetic graft. We present our single center experience of 140 brachiobasilic fistulas in a five-year period and examine any factors that influence patency and long-term function. Methods: Patients who had undergone formation of a BBAVF between January 2004 and January 2009 were identified; a review of all case notes and databases was undertaken. Details on demographics, cause of renal failure, co-morbidities (including diabetes, cardiac morbidity, hypertension, peripheral vascular disease), dialysis status at the time of fistula creation, hemoglobin, anti-coagulation regimens, and complications from surgery were recorded. Results: Patency (defined as use of AVF for dialysis) was 83% at 3 months, 77% at 6 months, and 69% at 12 months. Length of patency ranged from 0 to 1918 days (at study cut-off) with a mean patency of 532 days. Factors found to significantly affect fistula patency included age over 60 (P
Do arteriovenous fistulae cause technical/local complications after renal transplantation.
No full textEvaluation of the Effect of Pprocessing Parameters on Adhesion performance of Polyetherbased TPU over mold on to Polycarbonate Substrate
No full textThe overmolding process involves the use of two separate materials to form one cohesive component. The final product is a single piece, made out of polymers with very different mechanical properties that must be safe and permanently bonded together throughout its useful life. The first shot is generally a hard plastic and is referred to as a substrate the second material is generally a soft thermoplastic elostomer (TPE) and referred as overmold. The rigid substrate is used for structural purposes, and the softer materials are expected to take care of the user comfort. Overmolding can add immeasurable value to product design by enhancing the comforts for user, ergonomics, and ease of use. It finds applications in household appliances, hand tools, automotive interiors, hand held computers and medical devices. The most common problems with overmolding are insufficient chemical or mechanical bonding of the polymers, incomplete filling of one or more components, and flashing of overmold. This paper deals with adhesion issues and describes the study performed to evaluate the effect of processing parameters on adhesion performance of Polyether based TPU over mold on to Polycarbonate Substrate. The study established the effect of various processing parameters on the adhesion of overmold to substrate. In addition effect of various surface roughness of substrate on adhesion was also determined. Study also describes the criteria used to design specimen and the specimen tool was build. The specimens were molded using design of experiments. The specimens were tested using Inston universal testing machine by establishing the test procedure and test set up to yield consistent results. The force at which constant peel occurred, called peel force was determined for all experiments. The study concludes that melt temperature is the most dominating factor and the specimen molded with lower melt temperature results in good bond. Light roughness on the substrate surface further enhances the adhesion. Scanning electron microscopy was performed on the peeled samples showed higher peel force and lower peel forces. The SEM images were thoroughly reviewed. It was further concluded that the air entrapment at higher melt temperature reduces adhesion. The main source for air entrapment is from the gassing of plasticizers, oils and waxes used in TPE formulations. The author also proposes similar studies for various other combinations of substrate and TPE as a path forwar
Evaluation of the Effect of Pprocessing Parameters on Adhesion performance of Polyetherbased TPU over mold on to Polycarbonate Substrate
No full textThe overmolding process involves the use of two separate materials to form one cohesive component. The final product is a single piece, made out of polymers with very different mechanical properties that must be safe and permanently bonded together throughout its useful life. The first shot is generally a hard plastic and is referred to as a substrate the second material is generally a soft thermoplastic elostomer (TPE) and referred as overmold. The rigid substrate is used for structural purposes, and the softer materials are expected to take care of the user comfort. Overmolding can add immeasurable value to product design by enhancing the comforts for user, ergonomics, and ease of use. It finds applications in household appliances, hand tools, automotive interiors, hand held computers and medical devices. The most common problems with overmolding are insufficient chemical or mechanical bonding of the polymers, incomplete filling of one or more components, and flashing of overmold. This paper deals with adhesion issues and describes the study performed to evaluate the effect of processing parameters on adhesion performance of Polyether based TPU over mold on to Polycarbonate Substrate. The study established the effect of various processing parameters on the adhesion of overmold to substrate. In addition effect of various surface roughness of substrate on adhesion was also determined. Study also describes the criteria used to design specimen and the specimen tool was build. The specimens were molded using design of experiments. The specimens were tested using Inston universal testing machine by establishing the test procedure and test set up to yield consistent results. The force at which constant peel occurred, called peel force was determined for all experiments. The study concludes that melt temperature is the most dominating factor and the specimen molded with lower melt temperature results in good bond. Light roughness on the substrate surface further enhances the adhesion. Scanning electron microscopy was performed on the peeled samples showed higher peel force and lower peel forces. The SEM images were thoroughly reviewed. It was further concluded that the air entrapment at higher melt temperature reduces adhesion. The main source for air entrapment is from the gassing of plasticizers, oils and waxes used in TPE formulations. The author also proposes similar studies for various other combinations of substrate and TPE as a path forwardAdvisor(s): T A. Venkatesh. Committee Member(s): Miriam Rafailovich; Jonathan Sokolov; Vik Bhargava.Stony Brook University Libraries. SBU Graduate School in Department of Materials Science and Engineering. Lawrence Martin (Dean of Graduate School)
Clinical practice guideline on peri- and postoperative care of arteriovenous fistulas and grafts for haemodialysis in adults [Erratum]
No full textIn the original version, reference 35 had the incorrect journal title. This has now been amended. An additional affiliation has also been added for author Tamara Jemcov
