2,121 research outputs found

    Sichuan (China), lakes on the saddle below mountains

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    Lakes on the Hai-Tze-Shan saddle below Djara Peak.Image is part of research condcuted by J. Hanson-Lowe for the article: Notes on the Pleistocene Glaciation of the South Chinese-Tibetan Borderland Author(s): J. Hanson-Lowe Source: Geographical Review, Vol. 37, No. 1 (Jan., 1947), pp. 70-87 Published by: American Geographical Society Stable URL: http://www.jstor.org/stable/211362http://www.jstor.org/stable/211362Grayscal

    Sichuan (China), hanging valleys formed by glaciers

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    Hanging valley on left-hand wall of valley below, and to east of the Sara La.Image is part of research condcuted by J. Hanson-Lowe for the article: Notes on the Pleistocene Glaciation of the South Chinese-Tibetan Borderland Author(s): J. Hanson-Lowe Source: Geographical Review, Vol. 37, No. 1 (Jan., 1947), pp. 70-87 Published by: American Geographical Society Stable URL: http://www.jstor.org/stable/211362http://www.jstor.org/stable/211362Grayscal

    Impaired neural development in a zebrafish model for lowe syndrome

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    Lowe syndrome, which is characterized by defects in the central nervous system, eyes and kidneys, is caused by mutation of the phosphoinositide 5-phosphatase OCRL1. The mechanisms by which loss of OCRL1 leads to the phenotypic manifestations of Lowe syndrome are currently unclear, in part, owing to the lack of an animal model that recapitulates the disease phenotype. Here, we describe a zebrafish model for Lowe syndrome using stable and transient suppression of OCRL1 expression. Deficiency of OCRL1, which is enriched in the brain, leads to neurological defects similar to those reported in Lowe syndrome patients, namely increased susceptibility to heat-induced seizures and cystic brain lesions. In OCRL1-deficient embryos, Akt signalling is reduced and there is both increased apoptosis and reduced proliferation, most strikingly in the neural tissue. Rescue experiments indicate that catalytic activity and binding to the vesicle coat protein clathrin are essential for OCRL1 function in these processes. Our results indicate a novel role for OCRL1 in neural development, and support a model whereby dysregulation of phosphoinositide metabolism and clathrin-mediated membrane traffic leads to the neurological symptoms of Lowe syndrome. © The Author 2011. Published by Oxford University Press. All rights reserved

    Sichuan (China), view of mountains across from Litang plain

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    Looking across the Litang plain from somewhat east of that town. The "Lama's Hat" peak lies in the center of the picture and is flanked by corries.Image is part of research conducted by J. Hanson-Lowe for the article: Notes on the Pleistocene Glaciation of the South Chinese-Tibetan Borderland Author(s): J. Hanson-Lowe Source: Geographical Review, Vol. 37, No. 1 (Jan., 1947), pp. 70-87 Published by: American Geographical Society Stable URL: http://www.jstor.org/stable/211362http://www.jstor.org/stable/211362Grayscal

    I remember living at Seabrook, 1945-1953

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    In this "I remember" memoir, Ann Mariko Lowe recalls life at Seabrook, which introduced her to many new experiences, including Halloween traditions. She remembers the living conditions in the dorms at Seabrook, where there was little privacy, and poor facilities. Afterwards, her family moved to the apartments, where they were able to form close bonds with other Japanese families. This was especially helpful with expenses. Ann also played basketball at the Community Center, attended Bible study classes, and was a student at Seabrook School. The Seabrook Educational and Cultural Center has been soliciting current and past residents of Seabrook Farms for an "I remember" project. Residents are asked to create narratives regarding their experiences at Seabrook Farms. These memories help preserve the history and multi-cultural heritage of Seabrook Farms

    Developing future energy performance standards for UK housing: The St Nicholas Court project – Part 1

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    This paper (and Part 2, to appear in the next issue) set out the results of a housing field trial designed to evaluate the impact of an enhanced energy performance standard for dwellings. The project was designed to inform the next review of Part L of the Building Regulations for England and Wales, which, following the publication of the UK government's white paper on energy policy, is expected in 2005. The project explores the implications of an enhanced standard in the context of timber frame construction. Although for programming reasons it was necessary to terminate the research project at the end of the design phase, the results suggest that the standard investigated is well within the capacity of the industry but it was clear that the whole supply chain will need to take a positive approach to the development of new solutions. The secret to a smooth and cost optimised transition is for the necessary development work to begin immediately, not when regulation changes. © 2003, MCB UP Limite

    Gender and the culture of the English alehouse in late Stuart England

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    The world of the alehouse and tavern in early modern England has generally been regarded as primarily male, a view that was deeply embedded in the period itself. This essay explores the place of women within the public house, in serving, buying and consuming alcohol, and the unwritten conventions that underpinned social practice. It argues that while some female customers matched their contemporary image, as disorderly, immoral and dishonest, it was also possible for respectable women to visit a tavern or alehouse without risking their good name, provided they adhered to the conventions. Middling-sort and elite women might drink and dine in London taverns with their husbands, or in mixed parties; throughout England married couples, and mixed groups of young folk, might drink, dance, and socialise; marketwomen might assemble at the end of the day, and chapwomen often lodged overnight. And, at least in London, respectable women might enter a public house alone, by day, without meeting disapproval. Many establishments provided private as well as public rooms, and these created social spaces for female customers, couples and mixed parties, serving different needs than those met within the main public space

    Barbaracurus zambonellii Kovařík & Lowe & Šťáhlavský 2018, comb. n.

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    Barbaracurus zambonellii (Borelli, 1902) comb. n. (Figures 7, 28, 36, 58–61, 79–80, 88–89, 219–244, 248– 251, 261–262, 265, Table 1) Babycurus zambonellii Borelli, 1902: 1–4; Hirst, 1907: 209; Kraepelin, 1913: 181; Caporiacco, 1947: 232; Probst, 1973: 329; Lamoral & Reynders, 1975: 498; Kovařík, 1998: 104 (in part); Fet & Lowe, 2000: 80 (in part); Lowe, 2000: 185–191 (in part); Kovařík, 2000: 260–261 (in part); Kovařík, 2003: 137 (? in part); Chiarle et al., 2012: 21. TYPE LOCALITY AND HOLOTYPE DEPOSITORY. Eritrea, Chenafena; MZUT. MATERIAL EXAMINED. Eritrea, Chenafena (14.786N 39.018E), 1♀ (holotype), MZUT; Filfil, Salamuna river, 15°36'34.6"N 38°57'22.8"E, 817 m a.s.l., 3.-4.XI.2015, (Figs. 224–225, Locality No. 15 EH), 3♂ 3♀1♀ im.3juvs. (No. 876, Figs. 28, 36, 219–223, 226–244, 258–251, 258–259), leg. F. Kovařík, FKCP. DIAGNOSIS. Total length of adult males 32–35 mm, adult females 46–52 mm. Coloration yellowish brown to grey with darker markings, chelicerae yellow without or with traces of reticulation. Pedipalp chela manus much wider in male than female, chela length/width ratio 3.42 in males and 4.29 in female; proximal margins of pedipalp fingers of female straight (Figs. 61, 231), of male undulate so as to leave a gap with fingers closed (Figs. 59, 233); dentate margin of movable finger armed with 7 rows of granules, and a short apical row of 3–4 denticles (Fig. 7); most proximal granule row with one external accessory granule. Pectines with 17–19 teeth in both sexes. Hemispermatophore basal lobe a weak, oblique carina (Figs. 28, 36). Metasoma narrow, metasoma V length/width ratio is 2.40–2.46 in males and 2.56–2.58 in females (Figs. 76–77); metasoma I with 10 carinae, II–IV with 8 carinae. Telson setose, bearing numerous long macrosetae and short, pointed subaculear tubercle; vesicle smooth, elongate, ellipsoidal, slightly bulbous, telson length/depth ratio 2.27–2.37 in both sexes; aculeus slender, curved, shorter than vesicle. NOTE. In his original description, Borelli (1902: 3) assumed that the holotype was a male, and this was accepted by most subsequent authors. Only Lowe (2000: 190–191) questioned this assumption, observing that the holotype exhibited some characters more consistent with females of other species of Babycurus sensu lato, and noted that “Study of additional material is needed to clarify variation and sexual dimorphism in B. zambonellii ”. Recently, the first author (F.K.) was able to finally settle this question by collecting additional material representing both sexes of B. zambonellii. The new specimens clearly demonstrated that the holotype is indeed female, not male. B. zambonellii is an Eritrean endemic and the female which Sissom (1994) cited from Yemen represents a new species which we describe here as B. yemenensis sp. n. COMMENTS ON LOCALITY AND LIFE STRATEGY. The first author (F.K.) visited the locality 15EH (Figs. 224–225), a montane, forested habitat along a riverbed of an occasional river, on 3–4 November 2015. At this locality, the author recorded a maximum daytime temperature of 30.3 ºC, and minimum nighttime temperatures of 19.6 ºC. The recorded humidity was between 46% and 92%. In addition to B. zambonellii the first author also recorded Hottentotta minax (L. Koch, 1875) at this locality.Published as part of Kovařík, František, Lowe, Graeme & Šťáhlavský, František, 2018, Review of the genus Babycurus Karsch, 1886 (Arachnida, Scorpiones, Buthidae), with descriptions of Barbaracurus gen. n. and two new species from Oman and Yemen, pp. 1-41 in Euscorpius 267 on pages 33-36, DOI: 10.5281/zenodo.654415

    Neobuthus awashensis Kovarik et Lowe 2012

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    Neobuthus awashensis Kovařík et Lowe, 2012 (Figs. 1–6, 158, 161–165) Neobuthus awashensis Kovařík & Lowe, 2012: 7–16, figs. 5–6, 18–21, 34–38, 44–47, 67–74, 86, 89, 92, 95–96, 100–101; Kovařík et al., 2015: 30. TYPE LOCALITY AND TYPE REPOSITORY. Ethiopia, Awash, Metahara env., 08°54' N 39°54' E, 960-1050 m a.s.l., FKCP. TYPE MATERIAL. Ethiopia, Awash, Metahara env., 08°54' N 39°54' E, 960-1050 m a.s.l., 1♀ (paratype), 2008, leg. V. Trailin, 2♀1♀ im. (allotype and paratypes), XI.2010, leg. T. Mazuch and P. Novák, 32♂ (holotype and paratypes) 18♀ (paratypes) 11♀ ims, 5♂ ims (paratypes), 19.-22.VII.2011, leg. F. Kovařík. Most types are in the collection of the second author (FKCP), two paratypes (♂ ♀) are in the collection of the first author (GL). OTHER MATERIAL EXAMINED. Ethiopia, 11°43'22" N 40° 56'52" E, 457 m a.s.l. (Locality No. 12 EMA), 20.XI. 2012, 1♀1♀ im., leg. F. Kovařík (UV detection), FKCP; 11°43'30" N 40°58'45" E, 404 m a.s.l. (Locality No. 12EM), 20.XI.2012, 1♂, leg. F. Kovařík (UV detection), FKCP; Gewane, 10°09'38" N 40°39'45" E, 631 m a.s.l. (Locality No. 12 EO), 23.XI.2012, 1♂ 1♀, leg. F. Kovařík, (UV detection), FKCP; 09°08'10.4" N 40°09' 45.5" E, 835 m a.s.l. (Locality No. 12ER), 24.XI.2012, 12♂ 1♀ 1juv., leg. F. Kovařík (UV detection), FKCP, 26.-27.XI.2014, 8♂ 2♀ 2juvs, FKCP, 3♂ 2juvs, GL, leg. F. Kovařík; Awash, Metahara env., 08°54' N 39°54' E, 960-1050 m a.s.l. (Locality No. 12 EX), 25.XI.2012, 7♂ 6♀ 5juvs., 27.-30.XI.2014, 7♂ 1♀, topotypes, leg. F. Kovařík (UV detection), FKCP. EMENDED DIAGNOSIS. Total length 18–22 mm (males), 22.5–30 mm (females); carapace with area between anterior median carinae fuscous; tergites with fuscous pigmentation unbroken across median area; pedipalp relatively slender, males with femur L/ W 2.50 –2.70, patella L/ W 2.45 –2.70, chela L/ W 4.63 –5.08; chela movable finger with 5–6 subrows of primary denticles, 3–5 external accessory denticles flanking proximal end of each subrow; trichobothria d 2 usually absent from femur and patella; posterior margins of carapace and tergites usually bearing 2–4 macrosetae; pedipalps, legs, metasoma and telson with short, stout macrosetae in males, and long, fine setae in females; males with coxae sparsely granulated, sternites III–VI lightly shagreened to smooth, sternite VII finely granulated with 4 weak, granulated carinae; females with sternites III–VI smooth, sternite VII sparsely shagreened with 4 weak carinae, median carinae granulated; metasoma I–III with median lateral carinae present in both sexes; lateral surface of metasoma V in males densely granulated, with granules separated; soles of telotarsi with relatively sparse setation, leg III of adults with 6–9 macrosetae in retroinferior series of basitarsus, 12–19 ventral macrosetae on telotarsus; pectine teeth: 17–21 (males), 15–18 (females).Published as part of Lowe, Graeme & Kovařík, František, 2016, Scorpions of the Horn of Africa (Arachnida, Scorpiones). Part V. Two new species of Neobuthus Hirst, 1911 (Buthidae), from Ethiopia and Eritrea, pp. 1-46 in Euscorpius 224 on page

    Developing Future UK Energy Performance Standards: The St Nicholas Court project, Final Report

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    The St Nicholas Court Project was set up to explore the implications of an enhanced energy performance standard for new housing for the design, construction and performance of timber framed dwellings. The energy performance standard, EPS08, is modelled on proposals made by the DETR in June 2000 for a possible review of Part L of the Building Regulations in the second half of the present decade. The overall goal of the project was to support the next revision of Part L through an enhanced body of qualitative and quantitative evidence on options and impacts. The seeds of the project were contained in a report – Towards Sustainable Housing - commissioned by Joseph Rowntree Foundation at the start of the last review of this part of the Building Regulations. The project itself has been based on the St Nicholas Court Development which involves the design and construction of a group of 18 low energy and affordable dwellings on a brown field site in York (see site plan below). The research project was established in two stages. Initial funding was provided by the Joseph Rowntree Foundation in the spring of 1999. This ensured the involvement of the research team from the outset of the development process. Additional funding was provided from late 2000 by the Housing Corporation and by the DETR through the Partners in Innovation programme (responsibility for which now lies with the DTI). The research project was originally divided into five phases – project definition, design, construction, occupation, and communication and dissemination. Delays in site acquisition initially allowed the design phase to be extended, but ultimately forced the abandonment of the construction and occupation phases, and the scaling down of the communication and dissemination phase. Despite the delays, the development itself will now go ahead, with construction starting in mid-2003
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