147,640 research outputs found
The maternal immune system during pregnancy and its influence on fetal development
No full textThe maternal immune system plays a critical role in the establishment, maintenance, and completion of a healthy pregnancy. However, the specific mechanisms utilized to achieve these goals are not well understood. Various cells and molecules of the immune system are key players in the development and function of the placenta and the fetus. Effector cells of the immune system act to promote and yet limit placental development. The T helper 1 (Th1)/T helper 2 (Th2) immune shift during pregnancy is well established. A fine balance between proinflammatory and anti-inflammatory influences is required. We herein review the evidence regarding maternal tolerance of fetal tissues and the underlying cell-mediated immune and humoral (hormones and cytokines) mechanisms. We also note the many unanswered questions in our understanding of these mechanisms. In addition, we summarize the clinical manifestations of an altered maternal immune system during pregnancy related to susceptibility to common viral, bacterial, and parasitic infections, as well as to autoimmune diseases.Peer reviewe
King, Howell T., October 26, 2010 [Interview]
No full textHowell T. King was interviewed on October 26, 2010, by Nicholas Oristian about his experiences during and after World War II.Williams, Ted; Kimmel, BillWorld War I
Nicholas - Samuel T. Nicholas
No full textA.B.; A.M., 1893; D.D., 1916. Grad. Gettysburg Seminary, 1893. Born Apr. 23, 1869, Kintnersville. Brother of J.R.N., class of 1894. Lutheran clergyman: Pittsburgh, 1893-1905; Middletown, 1905-13; Keller Memorial, Washington, D.C., 1913- . Missionary pres., Pittsburgh Synod, 1902-05. Member, boards of Foreign Missions and Home Missions; councilman, Federation of Churches, U.S.A. Married June 7, 1894, Elizabeth Ellen Spangler, Arendtsville. Child, John Spangler, b. Mar. 10, 1895 (class of 1916). Address: 907 Maryland Ave., N.E., Washington D.C. Handwritten on back: ""Yours truly, S. T. Nicholas, Riegelsville, Pa."
The cult of St Nicholas in medieval Italy
No full textSt Nicholas was one of the most popular saints in medieval Italy. His cult attracted the attention
of popes, kings and emperors, and his shrine at Bari became an important international pilgrimage
destination. This thesis asks how the cult of St Nicholas came to be so widespread and popular in
Italy, and why the saint attracted the attention of diverse groups and individuals.
This thesis is structured around four chapters. The first demonstrates that through a
process of Latinisation the cult of St Nicholas became integrated within Italian literary traditions
and within a new spiritual era. Chapter Two reveals that this Latinisation also occurred within the
saint’s iconography. Chapters Three and Four are case studies of the cult in Puglia and Venice,
locations which claimed possession of the saint’s relics. These case studies show that the general
developments that the cult of St Nicholas underwent in Italy, identified in Chapters One and Two,
did not apply universally. Instead, the presence of the saint’s relics resulted in a different profile
of the saint in Bari and Venice. Through the process of Latinisation, the cult of St Nicholas
became updated and remained relevant for its new Italian audience; Chapters Three and Four
show alternative ways that the cult of St Nicholas gained widespread popularity.
This thesis presents for the first time an iconographical study of St Nicholas in Italian art,
which develops existing research of the saint’s Byzantine iconography. Chapter Four presents a
profile of the cult of St Nicholas in Venice in the Middle Ages, which is a significant oversight in
the literature. The thesis uses a variety of visual and textual sources, in particular fresco and
altarpiece representations, archival documents from Venice and Rome (including the Apostolic
Visitations), and under-exploited contemporary and antiquarian Venetian sources
Australian federalism: past, present and future tense
No full textGabrielle Appleby, Nicholas Aroney and Thomas Joh
External interventions and the duration of civil wars
No full textThe authors combine an empirical model of external intervention, with a theoretical model of civil war duration. Their empirical model of intervention allows them to analyze civil war duration, using"expected"rather than"actual"external intervention as an explanatory variable in the duration model. Unlike previous studies, they find that external intervention is positively associated with the duration of civil war. They distinguish partial third-party interventions that extend the length of war, from multilateral"peace"operations, which have a mandate to restore peace without taking sides - and which typically take place at war's end, or at least when both sides have agreed to a cease-fire. In a future paper, the authors will examine whether partial third-party interventions - whatever their effect on a war's duration - increase the risk of war's recurrence. If that proves true, then even if interventions reduce the length of civil war, they may do so at the cost of further destabilizing the political system, and sowing the seeds of future rebellion.Children and Youth,Peace&Peacekeeping,Post Conflict Reconstruction,Post Conflict Reconstruction,International Affairs,Post Conflict Reconstruction,Social Conflict and Violence,Peace&Peacekeeping,Post Conflict Reconstruction,International Affairs
Nicholas de Grandmaison with movie star Jack Oakie.
No full textBlack-and-white photograph of Nicholas de Grandmaison outside on a golf cart with Jack Oakie. Nicholas is on the back of the cart and is wearing a suit jacket, shirt and dark fedora. He has a pair of sunglasses and cigarette in one hand, and is leaning forward and looking at Jack. Jack is seating in the front seat of the golf cart and is dressed casually in collared t-shirt, light jacket and trousers. He is facing the camera and smiling while holding a framed portrait of a First Nations child wearing braids. Jack Oakie's name appears on the front of the golf cart and a dog sits to the side of the golf cart. There is a round shaped bush behind them. The golf cart appears to be on a road and in the background there is lawn, trees and a fence. A handwritten notation in pencil on the back of the photograph reads: "Dad with Jack Oakie, movie star". Title supplied by cataloguer
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