338,645 research outputs found
Modest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysis
No full textBackground: P53, egfr and her-2/neu are the most frequently studied molecular biological parameters in epithelial ovarian cancer, but their prognostic impact is still unequivocal. We performed a meta-analysis to more precisely estimate their prognostic significance. Methods: Published studies that investigated the association between p53, egfr and her-2/neu status and survival were identified. Meta-analysis was performed using a dersimonian-laird model. Publication bias was investigated using funnel plots and sources of heterogeneity were identified using meta-regression analysis. Results: A total of 62 studies were included for p53, 15 for egfr and 20 for her-2/neu. P53, egfr and her-2/neu status had a modest effect on overall survival (Pooled hr 1.47, 95% Ci 1.33-1.61 For p53; Hr 1.65, 95% Ci 1.25-2.19 For egfr and hr 1.67, 95% Ci 1.34-2.08 For her-2/neu). Meta-regression analysis for p53 showed that figo stage distribution influenced study outcome. For egfr and her-2/neu, considerable publication bias was present. Conclusions: Although p53, egfr and her-2/neu status modestly influences survival, these markers are, by themselves, unlikely to be useful as prognostic markers in clinical practice. Our study highlights the need for well-defined, prospective clinical trials and more complete reporting of results of prognostic factor studies. British journal of cancer ( 2009) 101, 149-159. Doi: 10.1038/Sj.Bjc.6605112 Www.Bjcancer.Com published online 9 june 2009 (C) 2009 Cancer research uk
Edward Neu, Dalton Wells Camp, general views
No full textImage shows a general view of the area of land near the Dalton Wells CCC Camp, near Moab.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
Edward Neu, Dalton Wells Camp, barracks
No full textImage shows a general view of the side of several barracks at the Dalton Wells CCC Camp, near Moab.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
Edward Neu, Dalton Wells Camp, enrollee reading
No full textImage shows an enrollee at the Dalton Wells CCC Camp, reading a paper while sitting on a chair inside his barrack.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
Edward Neu, Dalton Wells Camp, landscape
No full textImage shows a general view of an area of land near the Dalton Wells CCC Camp, near Moab.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
Edward Neu, Dalton Wells Camp, natural arches
No full textImage shows a natural arch formation near the Dalton Wells CCC Camp, near Moab.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
Edward Neu, Dalton Wells Camp, canyon
No full textImage shows a scenic view of a Colorado River canyon near the Dalton Wells CCC Camp, near Moab.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
Edward Neu, Dalton Wells Camp, two arches
No full textImage shows two natural arches near the Dalton Wells CCC Camp, near Moab.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
Edward Neu, Dalton Wells Camp, mountains
No full textImage shows a general view of a mountain area near the Dalton Wells CCC Camp, near Moab.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
Edward Neu, Dalton Wells Camp, cattle grazing
No full textImage shows a general view of an area of land near the Dalton Wells CCC Camp, near Moab.Edward Neu, the donor of this photo, was enrolled in the CCC from 1936 to 1937 at the Dalton Wells Camp. The Dalton Wells CCC Camp worked in conjunction with the U. S. Division of Grazing (DG or G)
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