118,031 research outputs found
Discorsi di architettura del senatore Giovan Batista Nelli : con la vita del medesimo ... : e du ragionamenti sopra le cupole /
No full textPortrait of the author by A.F. Ceccherelli after Giuseppe Zocchi.Signatures: A-B⁸ C-L⁴.Errata: p. [1] at end.Cicognara,Mode of access: Internet
The use of block-counts, mark-resight and distance sampling to estimate population size of a mountain-dwelling ungulate
No full textPopulation size estimates represent indispensable tools for many research programs and for conservation or management issues. Mountain ungulates in open areas are often surveyed through ground counts that normally underestimate population size. While the use of sample counts is desirable, few studies have compared different probabilistic approaches to estimate population size in this taxon. We compared the size estimates of a male population of Alpine chamois using mark-resight and line transect sampling methods, while block counts were used to obtain the minimum number of males alive in the study area. Surveys were conducted within the Gran Paradiso National Park (Italy), in August–September 2013, using block counts along purposely selected trails and vantage points, mark-resight over 5 consecutive resightings from vantage points and trails, and line transect sampling along 12 transects repeated 8 times. Block counts yielded a minimum number of males alive in the population of n = 72 individuals. This value was greater than the upper bound of the 95 % confidence interval achieved using line transect sampling {n = 54, CV = 14 % [95 % CI (40, 71)]} while mark-resight yielded a more realistic result of n = 93 individuals {CV = 18 % [95 % CI (63, 137)]}. Our results suggest that line transect sampling performed poorly in the Alpine environment, leading to underestimates of population size, likely due to violations of some assumptions imposed by the rugged nature of the terrain. The mark-resight yielded lower precision, possibly due to the limited number of marked individuals and resighting occasions, but it provided robustness and accurate estimates as marks were evenly distributed among animals
Le quattro relationi seguite in Ratisbona nelli tempi sotti notati.
No full textSignatures: A-B⁴C²; AC̲⁴D²; A⁴; A⁴B².l. Elettione del Rè de Romani à 22. decembre l636. in persona di S.M. Ferdinando III. Re d'Vngaria e Boemia -- 2. Incoronatione dell'istessa Maesta li 30. decembre 1636 -- 3. Balleto fatta nella Casa del Conseglio di detta città li 4. gennaro 1637 -- 4. Incoronatione della Regina de Romani à 7. detto.Mode of access: Internet
Sicilian Rock partridge (Alectoris graeca whitakeri): is the current protected area network enough?
No full textIs it true that pre-conization high-risk HPV DNA load is a significant factor of persistence of HPV infection after conization?
No full textMetal biomonitoring with mosses: procedures for correcting fro soil contamination
No full textHighly variable total concentrations of 15 elements have been found in five species of epigeic mosses growing in remote areas of Italy and in northern Victoria Land (continental Antarctica). It is very likely that soil particles entrapped in the mosses cause these high element concentration differences, thereby leading to inexact interpretations of baseline concentrations and of element distribution in different parts of mosses. A simple procedure for estimating more plausible background values that consists of subtracting the substratum contribution from raw concentrations of elements in mosses is reported. The normalization of total concentrations to the regional soil composition is also emphasized, in order to point out other possible metal sources. © 1995
Possible role of human herpesvirus 6 as a trigger of autoimmune disease
No full textHuman herpesvirus 6 (HHV-6) infection is common and has a worldwide distribution. Recently, HHV-6A and HHV-6B have been reclassified into two distinct species based on different biological features (genetic, antigenic, and cell tropism) and disease associations. A role for HHV-6A/B has been proposed in several autoimmune disorders (AD), including multiple sclerosis (MS), autoimmune connective tissue diseases, and Hashimoto's thyroiditis. The focus of this review is to discuss the above-mentioned AD associated with HHV-6 and the mechanisms proposed for HHV-6A/B-induced autoimmunity. HHV-6A/B could trigger autoimmunity by exposing high amounts of normally sequestered cell antigens, through lysis of infected cells. Another potential trigger is represented by molecular mimicry, with the synthesis of viral proteins that resemble cellular molecules, as a mechanism of immune escape. The virus could also induce aberrant expression of histocompatibility molecules thereby promoting the presentation of autoantigens. CD46-HHV-6A/B interaction is a new attractive mechanism proposed: HHV-6A/B (especially HHV-6A) could participate in neuroinflammation in the context of MS by promoting inflammatory processes through CD46 binding. Although HHV-6A/B has the ability to trigger all the above-mentioned mechanisms, more studies are required to fully elucidate the possible role of HHV-6A/B as a trigger of AD. © 2013 Francesco Broccolo et al
Effect of habitat improvement actions (HIAs) and reforestations on pheasants Phasianus colchicus in northern Italy
No full textProgressive multifocal leukoencephalopathy: what's new?
No full textProgressive multifocal leukoencephalopathy (PML), a severe demyelinating disease that is caused by human JC
polyomavirus, was first described as a complication of immune suppression 50 years ago and emerged as a major
complication of HIV infection in the 1980s. The prognosis has remained dismal since then, with discouraging results
from clinical trials of various therapeutic approaches, including immunomodulation and/or inhibition of viral replication.
PML is caused by reactivation of latent JC virus, and serotonergic 5-HT2a receptors have been identified as being critical
for viral infection of glial cells. In recent years, immunosuppressive therapeutic antibodies have been associated with an
increased incidence rate of PML. Here, the authors review findings on the pathogenesis of PML and the encouraging
case reports of novel treatments
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