320 research outputs found
Florius Infortunatus, scribe and author
No full textFinlayson Charles-P. Florius Infortunatus, scribe and author. In: Scriptorium, Tome 19 n°1, 1965. pp. 108-109
Plural wife: the life story of Mabel Finlayson Allred
No full textEdited by Martha Bradley-Evans.Includes bibliographical references.Introduction -- Martha Bradley-Evans; Preface -- Mabel Finlayson Allred; My Life Story -- Mabel Finlayson Allred; Postlude: Dedication to their parents -- The Allred children; "My Darling Mabel": Letters and poetry -- From Rulon C. Allred to Mabel Allred
The role of implicit wanting in relation to explicit liking and wanting for food : Implications for appetite control
No full textEating is an action open to awareness by the individual; however, it cannot be claimed that processes that control the expression of eating habits are necessarily explicit. This distinction between implicit and explicit processes may enhance understanding of the expression of food reward (particularly the concepts of liking and wanting [Berridge, K. C., & Robinson, T. E. (2003). Parsing reward. Trends in Neurosciences, 26, 507–513] and its importance for human appetite control [Finlayson, G. S., King, N. A., & Blundell, J. E. (2007b). Liking vs. wanting food: Importance for human appetite control and weight regulation. Neuroscience and Biobehavioural Reviews, in press]. The present study investigated the effect of meal-induced satiation on implicit and explicit processes of liking (L) and wanting (W) by developing a computer-based procedure to measure L and W in hungry and satiated states. Explicit measures were derived from analogue ratings whilst an implicit W measure was derived from reaction time in a forced-choice procedure, which also identified food preferences. Seventy subjects (21.8±0.9 years, BMI: 22.2±0.5 kg/m2) completed the procedure before and immediately following consumption of a savoury test meal. Satiation caused explicit ratings of L and W to decrease in all food categories (p<0.01); but with a more marked decrease for savoury foods compared with sweet foods (p<0.01). Implicit W was increased for sweet categories (p<0.01), but not for savoury. Implicit and explicit measures of L and W independently correlated with preference for sweet foods. This study provides support that implicit and explicit processes of food reward can be simultaneously measured and dissociated using a test meal. Adjustments in hunger were linked to changes in explicit L and W in a manner consistent with sensory specific satiety, while a relationship between hunger and implicit W was absent. We suggest that implicit W is not systematically downregulated by the physiological consequences of food consumption in the same way as hunger and therefore may be largely independent of homoeostatic processes influencing intake.\ud
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Liking vs. wanting food : importance for human appetite control and weight regulation
No full textCurrent train of thought in appetite research is favouring an interest in non-homeostatic or hedonic (reward) mechanisms in relation to overconsumption and energy balance. This tendency is supported by advances in neurobiology that precede the emergence of a new conceptual approach to reward where affect and motivation (liking and wanting) can be seen as the major force in guiding human eating behaviour. In this review, current progress in applying processes of liking and wanting to the study of human appetite are examined by discussing the following issues: How can these concepts be operationalised for use in human research to reflect the neural mechanisms by which they may be influenced? Do liking and wanting operate independently to produce functionally significant changes in behaviour? Can liking and wanting be truly experimentally separated or will an expression of one inevitably contain elements of the other? The review contains a re-examination of selected human appetite research before exploring more recent methodological approaches to the study of liking and wanting in appetite control. In addition, some theoretical developments are described in four diverse models that may enhance current understanding of the role of these processes in guiding ingestive behaviour. Finally, the implications of a dual process modulation of food reward for weight gain and obesity are discussed. The review concludes that processes of liking and wanting are likely to have independent roles in characterising susceptibility to weight gain. Further research into the dissociation of liking and wanting through implicit and explicit levels of processing would help to disclose the relative importance of these components of reward for appetite control and weight regulation
Fluorescence lifetime imaging with distance and ranging for biomedical endoscopic applications
No full textEndoscopic cameras play a vital role in medical diagnostics as they provide a minimally invasive way to image inside the body. Conventional cameras, however, are reliant on the use of white light which does not offer any additional diagnostic information over cues from colour and intensity.
Fluorescence lifetime imaging (FLIm) is a technique that can enhance endoscopy by providing differentiation between tissue types without the need
for biomarkers. This could be particularly valuable, for example, in the identification of cancerous tissue margins pre-intervention.
Time resolved arrays which incorporate single photon avalanche diodes (SPADs) are a prime candidate for FLIm as they offer very fast and precise
measurements of individual photon arrival times. In addition, they are able to obtain high speed images, even in low light conditions such as typically
observed in FLIm of endogenous fluorophores in the human body.
Another time resolved technique enabled by SPADs is time of flight (ToF) imaging which allows the distance to a target to be determined. ToF based
distance mapping could provide crucial depth perception which FLIm images inherently lack. In the case of endoscopic imaging, this allows for greater
camera and instrument control which in turn mitigates the risk of tissue damage during surgical procedures.
This research presents a combined fluorescence lifetime imaging with distance and ranging (FLImDAR) technique, realised through the use of SPAD
arrays. The FLImDAR modality has strong applications in clinical endoscopic imaging and thus is the focus of this research. Similar previous studies have
investigated depth measurements using deep tissue fluorescence which requires the addition of fluorescent dyes. This work, however, targets surface
auto-fluorescence.
Firstly, a computational model is used to examine and refine various algorithms which can be implemented to perform FLImDAR. This model is
used to decide the final FLImDAR technique, as well as investigate the impact of signal noise. Next, FLImDAR is demonstrated experimentally using
fluorescent polymer targets. Three SPAD sensors (MegaFrame, Quanticam and Endocam) are tested for compatibility with the FLImDAR modality, each
showcasing different strengths and limitations. To further prove FLImDAR’s ability to perform in low photon level auto-fluorescent applications, ovine and cancerous human pulmonary targets are imaged. The final part of this study regards performing FLImDAR with a miniaturised imaging system. The SPAD sensor, Endocam, is characterised prior to integration into a handheld camera. Using the handheld camera, FLIm videos of ovine tissue are captured as well as long exposure FLImDAR images.
With further advances in detectors, sensor architecture and photon budgets, this research indicates the significant performance improvements that will enable practical clinical application of the FLImDAR technique
Red-shifted environmental fluorophores and their use for the detection of Gram-negative bacteria_raw spectral data
No full textSpectral data (absorption, fluorescence, lifetime) of merocyanine derivatives described in the research article entitled "Red-shifted environmental fluorophores and their use for the detection of Gram-negative bacteria" published in Chemosensors (2021); The dataset contains absorption, fluorescence, and lifetime raw data on compounds numbered 1, 2, 12 and 13 in the article.Megia-Fernandez, Alicia; Klausen, Maxime; Mills, Beth; Brown, Gillian E.; McEwan, Heather; Finlayson, Neil; Dhaliwal, Kevin; Bradley, Mark. (2021). Red-shifted environmental fluorophores and their use for the detection of Gram-negative bacteria_raw spectral data, [dataset]. University of Edinburgh. https://doi.org/10.7488/ds/3041
First Sicamous Boy Scout troop
No full textHarold Palmer was Boy Scout leader at this time. Names not in order : Barry Seed, Lionel Seed, Gordon Allk, Neil Finlayson, George Maier.PH note: Originally ingested 20180209. Global Edit applied 20191010 with correct accessIdentifier: SICA_01_33
Eagle Valley School students
No full textBack: Eva Adams, Neil Finlayson, Billy Ahola, Aina Nordin, Betty (m. McBeath) Cameron (teacher). Middle: Annilli Reinikka, Gunnard Reinikka. Front: Valerie Stepp, Frances Peck, Betty Rauma.PH note: Originally ingested 20171207. Global edit applied 20191010, with correct accessIdentifier: SICA_01_12
Diet-induced obesity : when does consumption become overconsumption?
No full textOverconsumption is commonly implicated in the aetiology of obesity; however there is a lack of consensus on a definition and the most appropriate methodology for assessing it. The aim of this communication is to highlight the need for theoretical consensus on the assessment of overconsumption, which may lead to improved methodological standards in obesity research. In laboratory studies, overconsumption is most frequently inferred from the comparison of food intake within or between individuals against a single control. Measurement often relies on a single eating episode with limited consideration of preceding or subsequent intake. An alternative approach is to consider food intake in the context of energy requirements, within an energy balance framework. One such marker of chronic overconsumption is body weight. There is a need for agreement on the definition and measurement of overconsumption, so that its role in weight gain and obesity can be more precisely delineated
RETRACTED: Experimental and Theoretical Investigation of Aerosol Optical Properties
No full textThis article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).This article has been retracted at the request of the Authors.It was prepared by Yan Li and Rui Xue, submitted by Yan Li, and published without the knowledge of the listed co-authors M.J. Ezell and B.J. Finlayson-Pitts. The experimental results are not interpretable as put forth in the published paper.The author Yan Li would like to apologize for the inconvenience caused to the co-authors and the readers
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