650 research outputs found
A short investigation of the effect of an energy harvesting backpack on the human gait
No full textExploiting human motion for the purpose of energy harvesting has been a popular idea for some time. Many of the approaches proposed can be uncomfortable or they impose a significant burden on the person's gait. In the current paper a hardware in-the-loop simulator of an energy harvesting backpack is employed in order to investigate the effect of a suspended-load backpack on the human gait. The idea is based on the energy produced by a suspended-load which moves vertically on a backpack while a person walks. The energy created from such a linear system can be maximised when it resonates with the walking frequency of the person. However, such a configuration can also cause great forces to be applied on the back of the user. The system which is presented here consists of a mass attached on a rucksack, which is controlled by a motor in order to simulate the suspended-load backpack. The advantage of this setup is the ability to test different settings, regarding the spring stiffness or the damping coefficient, of the backpack harvester, and study their effect on the energy harvesting potential, as well as on the human gait. The present contribution describes the preliminary results and analysis of the testing of the system with the help of nine male volunteers who carried it on a treadmill
The mitochondrial T1095C mutation increases gentamicin-mediated apoptosis
No full textAbstract not availableHakan Muyderman, Neil R. Sims, Masashi Tanaka, Noriyuki Fuku, Ravinarayan Raghupathi, Dominic Thyagaraja
Methadone maintenance outcome as a function of detoxification phobia
No full texttag=1 data=Methadone maintenance outcome as a function of detoxification phobia.
tag=2 data=Milby, Jesse B.%Hohmann, Ann A.%Gentile, Mary%Huggins, Norman%Sims, Mary Kaye%McLellan, Thomas%Woody, George%Haas, Neil
tag=3 data=American Journal of Psychiatry, Vol 151 no. 7, p. 1031-1037.
tag=6 data=^d ^mJuly ^y1994
tag=8 data=DRUGS
tag=9 data=METHADONE
tag=15 data=JO
Synthesis of furanosesquiterpenoid natural products
No full textThe effect of addition of a catalytic quantity of a crown ether in the reaction of a phosphonate anion with a carbonyl compound (Wadsworth-Emmons reaction) has been studied and found to greatly facilitate this reaction. This modification of the Wadsworth-Emmons reaction, using a catalytic amount of 15-crown-5, has been employed in the synthesis of the naturally occurring furanosesquiterpene Pallescensin-E. The structure of this compound has been confirmed by comparison of its spectral data with that of the synthesised isomer, 4,l0-dihydro-7,8-dimethyl 10H-benzof4,5Jcycloheptafl,2-bJ furan.Homosesquirosefuran, an analogue of the naturally occurring furanosesquiterpene Sesquirosefuran, has been synthesised via the dianion of methylacetoacetate.An approach to the synthesis of Pinguisone (a component of the essential oil of the liverwort Aneura pinguis)has been attempted employing two Diels-Alder reactions to generate the four cis-methyl groups found in the natural product.In a study of the reaction of n-(2-methylallyl)nickel bromide complex with a range of epoxides, this complex was found not only to react with reactive epoxides (e.g. styrene epoxide) but also with less reactive propylene epoxide.Substrates for possible intramolecular n-allylnickel cyclisation to generate an a-methylene-6-valerolactone ring system have been prepared
Autonomous characters in virtual environments: The technologies involved in artificial life and their affects on perceived intelligence and playability of computer games
Get PDFComputer games are viewed by academics as un֊grounded hack and patch experiments. "The industry lacks the formalism and requirement for a "perfect" solution often necessary in the academic world " [Woob]. Academic Artifical Intelligence (AI) is often viewed as un-implementable and narrow minded by the majority of ทon-AI programmer. "Historically, AI tended to be focused, containing detailed problems and domain-specific techniques. This focus makes for easier study - or engineering - of particular solutions. " [СһаОЗ .By implementing several well known AI techniques into the same gaming environment and judging users reactions this project aims to make links between the academic nature of AI, as well as investigate the nature of practical implementation in a gaming environment. An online Java implemented version of the 1970'ร classic Space Invaders has been developed and tested, with the Aliens being controlled by 6 different approaches to modelling AI functions. In total information from 334 individuals games was recorded. Different types of games AI can create highly varied gaming experience as highlighted by the range of values and high standard deviation values seen in the results. The link between complex behaviour, complex control systems and perceived intelligence was not supported. A positive correlation identified between how fun the users found the game and how intelligent they perceived the Aliens to be, would seem to be logical. As games get visually more and more impressive, the need for intelligent characters cannot be denied because it is one of the few way in which games can set themselves apart from the competition. Conclusions identified that computer games must remain focussed on their end- goal, that of producing a fun game. Whilst complex and clever AI can help to achieve it, the AI itself can never overshadow the end result
Losses of NG2 and NeuN immunoreactivity but not astrocytic markers during early reperfusion following severe focal cerebral ischemia
No full textDiane R. Lee, Stephen C. Helps, Ian L. Gibbins, Michael Nilsson, Neil R. Sim
Analysis of Process Damping in Milling
No full textAbstractRegenerative chatter has been identified as one of the major limitations on achieving higher material removal rates in milling. There are numerous studies in the literature in which various time and frequency domain models have been developed and successfully employed to predict stability boundaries for different milling operations. However, many of these studies have neglected the dynamics of tool – workpiece interaction that describes process damping. As this interaction becomes prominent at low speeds, it enables substantially higher chatter-free depths that would be of great importance especially for difficult-to-cut alloys. In this study, an alternative process damping model has been presented for flat-end milling on the basis of an equivalent viscous damping approach. Parameters included in the process damping model are cutting speed, vibration amplitude, wear land width and clearance angle. Computed stability diagrams show an agreement with cutting tests which were carried out on Ti6Al4V. The model demonstrates strong dependence to vibration amplitude. Also, it is shown that the spindle's low-frequency vibration mode governs the dynamics of process damping at low speeds
Recommended from our members
Insulin Sensitivity and Blood Pressure
No full textHypertension, glucose intolerance, obesity, and hyperlipidemia are extremely prevalent problems in Western society, and each confers increased risk for coronary heart disease (CHD; Donahue, Skyler, Schneiderman, & Prineas, 1990). This cluster of disorders is so commonly associated as to suggest common pathogenetic mechanisms. Hyperinsulinemia and insulin resistance have been proposed to be the underlying link between these disorders (Christlieb, Krolewski, Warram, & Soeldner, 1985; Donahue et al., 1990; Ferrari & Weidmann, 1990; Krieger & Landsberg, 1988; Reaven & Hoffman, 1987; Sims, 1982; Swislocki, 1990), which collectively have been dubbed the GOH (glucose intolerance–obesity–hypertension) syndrome by Modan et al. (1985), "Syndrome X" by Reaven (1988), the "deadly quartet" by Kaplan (1989), the "chronic disease risk factor syndrome" by Zimmet (1989), and the "insulin resistance syndrome" by DeFronzo and Ferrannini (1990)
- …
