1,721,195 research outputs found
Coronary atherosclerosis and quantitative myocardial perfusion: A relationship beyond stenosis
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Emerging F-18-Labelled PET Myocardial Perfusion Tracers
No full textPurpose of Review: PET myocardial perfusion imaging (MPI) is an established modality for the evaluation of ischemic heart disease and quantitation of myocardial blood flow (MBF). New F-18-labelled radiopharmaceuticals have been recently developed to overcome some of the limitations of currently used tracers such as the need of an on-site cyclotron. The characteristics of the new tracers and the clinical results obtained so far will be reviewed. Recent Findings: Most of the interest in the field of 18F-labelled radiotracers for PET MPI has been concentrated on MC-1 inhibitors, the prototype of which is 18F-flurpiridaz. It was shown in experimental and clinical reports that these radiotracers allow good quality rest/stress MPI studies and a reliable quantitation of MBF. Summary: Recent evidence suggests that PET MPI with 18F-flurpiridaz may provide a superior diagnostic accuracy for obstructive CAD even if a large comparative clinical trial with SPECT is still ongoing
Myocardial perfusion and coronary microcirculation: From pathophysiology to clinical application
No full textMyocardial perfusion and coronary microcirculation: from pathophysiology to clinical application.
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BLS FOR HEALTHCARE PROVIDERS-INSTRUCTOR MANUAL (Manuale Istruttore per Soccorritori BLS)
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