79,691 research outputs found
Tikuna bilineata Needham & Murphy, comb. n.
No full textTikuna bilineata (Needham & Murphy) comb. n. Choroterpes bilineata Needham & Murphy 1924: 48; Traver 1947: 156. The genus Tikuna was established by Savage et al. (2005) and Choroterpes atramentum Traver, 1947, was designated as the type species. Following this publication, two species from South and Central America remain incorrectly placed in Choroterpes. The first, Choroterpes bilineata Needham & Murphy, 1924, originally described from female imagos and male subimagos from La Chorrera, Putumayo Dist., Peru (now a part of Colombia), also belongs to the genus Tikuna, requiring the new combination Tikuna bilineata. The holotype and paratypes (Cornell University) were studied by one of us (H.M. Savage); additional specimens deposited at the U. S. National Museum of Natural History, Florida A&M University, and the Zoologische Sammlung des Bayerischen Staates were recorded from Brazil, Ecuador, Surinam, and Venezuela. New records for T. bilineata follow: BRAZIL: 1 female imago, Pará State, Rio Cururu, about 100 km above Mission Cururu, at light, 25 –I– 1962, E.J. Fittkau. ECUADOR: Pastaza Prov., coll. J. Cohen: 37 female imagos, Tzapino, 32 km NE Tigueno, 1 ° 11 ' S, 77 ° 14 ' W, 400 m, 25 –V– 1976; 2 female imagos, Limoncocha (70 miles SE), 30 –V– 1976; 3 female imagos, Cononaco, 30 –V– 1976. SURINAM: 1 female imago, Wijne Dist., Moengo, Boven, 1 / 28 –V– 1927, P.P. Babiy. VENEZUELA: Zulia State: 1 male subimago, Dist. Mara, Río Socuy, Campamento Corpozulia, 50 km W of Carrasquero, 6 / 7 –X– 1979, H.M. Savage & R.A. Romero; 1 female imago, Perija El Tucuco, Mission El Tucuco, Río El Tucuco, 1 / 2 km from church, 1 / 5 –X– 1979, H.M. Savage.Published as part of Peters, J. G., Flowers, R. W., Hubbard, M. D., Domínguez, E. & Savage, H. M., 2005, New records and combinations for Neotropical Leptophlebiidae (Ephemeroptera), pp. 51-60 in Zootaxa 1054 on page 52, DOI: 10.5281/zenodo.17006
Model based defect characterization in composites
No full textWork is reported on model-based defect characterization in CFRP composites. The work utilizes computational models of the interaction of NDE probing energy fields (ultrasound and thermography), to determine 1) the measured signal dependence on material and defect properties (forward problem), and 2) an assessment of performance-critical defect properties from analysis of measured NDE signals (inverse problem). Work is reported on model implementation for inspection of CFRP laminates containing multi-ply impact-induced delamination, with application in this paper focusing on ultrasound. A companion paper in these proceedings summarizes corresponding activity in thermography. Inversion of ultrasound data is demonstrated showing the quantitative extraction of damage properties.This proceeding may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing.
This proceeding appeared in Roberts, R., and S. Holland. "Model based defect characterization in composites." In AIP Conference Proceedings, vol. 1806, no. 1, p. 090015. AIP Publishing LLC, 2017, and may be found at
DOI: 10.1063/1.4974659.
Copyright 2017 Author(s).
Posted with permission
Verifying security protocols by knowledge analysis
No full textThis paper describes a new interactive method to analyse knowledge of participants involved in security protocols and further to verify the correctness of the protocols. The method can detect attacks and flaws involving interleaving sessions besides normal attacks. The implementation of the method in a generic theorem proving environment, namely Isabelle, makes the verification of protocols mechanical and efficient; it can verify a medium-sized security protocol in less than ten seconds. As an example, the paper finds the flaw in the Needham-Schroeder public key authentication protocol and proves the secure properties and guarantees of the protocol with Lowe's fix to show the effectiveness of this method
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Liftings for noncomplete probability spaces
No full textThe current state of knowledge concerning liftings for noncomplete probability spaces is discussed. This is a somewhat expanded version of the author's talk given at the 1991 Summer Conference on General Topology and Applications in Honor of Mary Ellen Rudin and Her Work.PT: S; CR: BURKE MR, IN PRESS P AM MATH S BURKE MR, 1991, ISRAEL J MATH, V73, P33 BURKE MR, 1992, ISRAEL J MATH, V79, P289 CARLSON T, THEOREM LIFTING CHRISTENSEN JPR, 1974, TOPOLOGY BOREL STRUC FREMLIN DH, 1989, HDB BOOLEAN ALGEBRAS, P877 INOESCUTULCEA A, 1966, 5TH P BERK S MATH ST, V2 IONESCUTULCEA A, 1967, CONTRIBUTIONS PROB 1, P63 IONESCUTULCEA A, 1969, TOPICS THEORY LIFTIN JECH TJ, 1978, SET THEORY JOHNSON RA, 1980, P AM MATH SOC, V80, P234 JUST W, IN PRESS T AM MATH S KUPKA J, 1983, INDIANA U MATH J, V32, P717 LOSERT V, 1983, LNM, V1080, P95 MAHARAM D, 1958, P AM MATH SOC, V9, P987 SHELAH S, 1983, ISRAEL J MATH, V45, P90 TALAGRAND M, 1982, P AM MATH SOC, V84, P379 VONNEUMANN J, 1931, CRELLES J MATH, V165, P109; NR: 18; TC: 0; J9: ANN N Y ACAD SCI; PG: 4; GA: BZ86BSource type: Electronic(1
Directly imaging the localisation and photosensitization properties of the pan-mTOR inhibitor, AZD2014, in living cancer cells
No full textThe range of cellular functions the mechanistic target of rapamycin (mTOR) protein performs makes it an attractive drug target for cancer therapy. However, the cellular localisation and mode of action of second generation inhibitors of mTOR is poorly understood despite the level of attention there is in targeting the mTOR protein. We have therefore studied the properties of the pan-mTOR inhibitor AZD2014, an ideal candidate to study because it is naturally fluorescent, characterising its photochemical properties in solution phase (DMSO, PBS and BSA) and within living cells, where it localises within both the nucleus and the cytoplasm but with different excited state lifetimes of 4.8 (+/− 0.5) and 3.9 (+/− 0.4) ns respectively. We measure the uptake of the inhibitor AZD2014 (7 μM) in monolayer HEK293 cells occurring with a half-life of 1 min but observe complex behaviour for 3D spheroids with the core of the spheroid showing a slower uptake and a slow biphasic behaviour at longer times. From a cellular perspective using fluorescence lifetime imaging microscopy AZD2014 was found to interact directly with GFP-tagged mTORC1 proteins including the downstream target, S6K1. We observe light sensitive behaviour of the cells containing AZD2014 which leads to cell death, in both monolayer and spheroids cells, demonstrating the potential of AZD2014 to act as a possible photodynamic drug under both single photon and multiphoton excitation and discuss its use as a photosensitizer. We also briefly characterise another pan-mTOR inhibitor, INK128
Bevan, A., Northover, P., Bray, P., Bonacchi, C., Colledge, S., Crellin, R., Gwilt, A., Hamilton, H., Hart, P., Kaleta, R., Keinan-Schoonbaert, A., Knight, M., Laws, K., Lodwick, M., Martinón-Torres, M., Needham, S., O'Connor, B., Perrucchetti, L., Pett, D., Wexler, J., Wilkin, N. (2024) A Catalogue of British Bronze Age Axeheads [data-set]. York: Archaeology Data Service [distributor] https://doi.org/10.5284/1122315
No full textThis archive provides a dataset of database data from a dataset list of roughly 8000 Bronze Age British axeheads, alongside associated elemental analyses, isotopic measurements and radiocarbon dates. It integrates several major existing data collection efforts and published catalogues, whilst also providing a basic typology.Bevan, A., Northover, P., Bray, P., Bonacchi, C., Colledge, S., Crellin, R., Gwilt, A., Hamilton, H., Hart, P., Kaleta, R., Keinan-Schoonbaert, A., Knight, M., Laws, K., Lodwick, M., Martinón-Torres, M., Needham, S., O'Connor, B., Perrucchetti, L., Pett, D., Wexler, J., Wilkin, N. (2024) A Catalogue of British Bronze Age Axeheads [data-set]. York: Archaeology Data Service [distributor] https://doi.org/10.5284/112231
Recommended from our members
Uncovering the truth behind Vygotsky's cognitive apprenticeship: engaging reflective practitioners in the 'master-apprentice' relationship
No full textIn recent years theories of situated cognition sharing the idea that learning and doing are inseparable as part of a process of enculturation, largely based upon the work of Vygotsky in developing a model of ‘cognitive apprenticeship’, have received much attention in education (Vygotsky, 1978) as an insightful model underpinning forms of learning and teaching. The master-apprentice relationship using techniques of apprenticeship such as modelling, scaffolding and reflection has since been used as a base for considerable research helping researchers and practitioners to understand teacher-student action across a range of different teaching situations (Collins et al., 1989; Hennessy, 1993; Jarvela, 1995; Rojewski et al., 1994). The focus of much of this research has explored the efficacy of the model when set against the question of how to improve forms of learning and teaching in particular settings
R Code and Output Supporting: Do Capture and Survey Methods Influence Whether Marked Animals are Representative of Unmarked Animals?
No full textThe archive consists of 9 files:
1. WA_elk.R = R code used to analyze elk resighting data.
2. WA_elk.html = html output resulting from running the R code in WA_elk.R.
3. Mtg_AK_WA.R = R code used to analyze mountain goat resighting data.
4. Mtg_AK_WA.html = html output resulting from running the R code in Mtg_AK_WA.R.
5. Moose_MN.R = R code used to analyze moose resighting data.
6. Moose_MN.html = html output resulting from running the R code in Moose_MN.R.
7. sightdat.csv = resighting data collected from moose in Minnesota between 2004 and 2007.
8. MTG_Sight_Alaska.csv = resighting data collected from mountain goats in Alaska.
9. NE_MN_Map.pdf = map of collection region for moose resighting data.These files contain R code (along with associated output from running the code) supporting all results reported in "Do Capture and Survey Methods Influence Whether Marked Animals are Representative of Unmarked Animals?" in Wildlife Society Bulletin. The lead author wrote this code to analyze multi-year re-sighting data collected from moose (Alces alces) in Minnesota, elk (Cervus elaphus) in Washington, and mountain goats (Oreamnos americanus) in Washington and Alaska, to evaluate whether detection probabilities increased or decreased as a function of time since animals were captured.Fieberg, John R; White, Kevin S. (2015). R Code and Output Supporting: Do Capture and Survey Methods Influence Whether Marked Animals are Representative of Unmarked Animals?. Retrieved from the University Digital Conservancy, http://dx.doi.org/10.13020/D6Z597
Open access self-archiving: An author study
No full textThis, our second author international, cross-disciplinary study on open access had 1296 respondents. Its focus was on self-archiving. Almost half (49%) of the respondent population have self-archived at least one article during the last three years. Use of institutional repositories for this purpose has doubled and usage has increased by almost 60% for subject-based repositories. Self-archiving activity is greatest amongst those who publish the largest number of papers. There is still a substantial proportion of authors unaware of the possibility of providing open access to their work by self-archiving. Of the authors who have not yet self-archived any articles, 71% remain unaware of the option. With 49% of the author population having self-archived in some way, this means that 36% of the total author population (71% of the remaining 51%), has not yet been appraised of this way of providing open access. Authors have frequently expressed reluctance to self-archive because of the perceived time required and possible technical difficulties in carrying out this activity, yet findings here show that only 20% of authors found some degree of difficulty with the first act of depositing an article in a repository, and that this dropped to 9% for subsequent deposits. Another author worry is about infringing agreed copyright agreements with publishers, yet only 10% of authors currently know of the SHERPA/RoMEO list of publisher permissions policies with respect to self-archiving, where clear guidance as to what a publisher permits is provided. Where it is not known if permission is required, however, authors are not seeking it and are self-archiving without it. Communicating their results to peers remains the primary reason for scholars publishing their work; in other words,
researchers publish to have an impact on their field. The vast majority of authors (81%) would willingly comply with a mandate from their employer or research funder to deposit copies of their articles in an institutional or subject-based repository. A further 13% would comply reluctantly; 5% would not comply with such a mandate
- …
