16 research outputs found
Association between metabolic health status and chronic kidney disease in the population of the northern region of Senegal: a cross-sectional study
No full textAbstract Introduction Chronic kidney disease (CKD) is a major public health problem worldwide. Data have shown the deleterious effects of metabolic abnormalities such as diabetes, hypertension and dyslipidemia on the occurrence of CKD. Obesity also contributes to this deterioration of kidney function. The objective of this study was to examine the proportion CKD and its associated risk factors within the different categories of metabolic health status. Patients and methods We conducted a cross-sectional study in the general population of three northern regions in Senegal using a two-level cluster sampling method. The sample was constituted with a precision of 5%, a power of 80% and a 10% attrition margin. Individuals aged 18–80 years were included in the study after giving their consent. Pregnant women, hospitalized persons within the past three months, patients with general or urinary symptoms within the past seven days and individuals undergoing kidney replacement therapy were excluded. Clinical and biological data were collected at participants’ homes by investigators using a modified version of the world health organization (WHO)’s STEPwise questionnaire. Results A total of 2439 participants were included in the study with a mean age of 45.4 ± 16.0 years and a sex ratio M: F of 2:5. Overall proportion of Metabolically Healthy No Obesity (MH-NO), Metabolically Unhealthy No Obesity (MU-NO), Metabolically Healthy Obesity (MH-O) and Metabolically Unhealthy Obesity (MU-O) were 79.9%, 9.1%, 10.5% and 8.4% respectively. Four hundred and thirty-five participants (17.8%) had CKD. Prevalence rates of CKD were higher among metabolically unhealthy phenotype participants regardless their body mass index (BMI), 27.0% in MU-NO and 27.8% in MU-O. In metabolically healthy participants those with obesity had a higher proportion of CKD (20.2%) compared to those without obesity (15.2%). In univariate analysis, MH-O and MU-O were significantly associated with CKD. In multivariate adjusted analysis, the odds of having CKD were higher in MU-O (OR: 2.15; 95% CI: 1.53, 2.98) and MU-NO (OR: 2.07; 95% CI: 1.49, 2.84) in the crude model. However, the association was not significative after adjustment for potential confounders. Conclusion Unhealthy metabolic phenotype and obesity were common in this cohort and were associated with a significant high prevalence of CKD compared to healthy participants. That prevalence appears to be even higher in individuals with both metabolically unhealthy phenotype and obesity
Dietary salt intake and kidney function in rural Senegalese populations: a cross-sectional study
No full textAbstract Introduction High salt intake is a major risk factor for hypertension and its complications such as chronic kidney disease (CKD) and cardiovascular diseases. The present study aimed to determine level of sodium consumption and its relation with kidney function in the rural populations of Ferlo (centre of Senegal). Subjects and methods We performed a cross-sectional study including 400 volunteers aged > 18 years. Clinical, biological and dietary data were collected during household visits. Daily sodium intake was measured in the 24 h-urine outpout and CKD was defined as eGFR 60 years, overweight and CKD. However, gender and hypertension were not significantly associated with salt intake. Industrial broths (91.5%) and bread (85%) represented the main sources of dietary salt. Conclusion This study revealed high levels of daily salt intake contrasting with low potassium intakes in the majority of participants. Participants with CKD, overweight and age > 60 years presented higher salt consumption. Stategies to reduce salt consumption are urgently needed to reduce burden of CKD in rural Senegalese populations
Prevalence of Chronic Kidney Disease among Diagnosed and Undiagnosed Hypertensive Individuals in the General Population of the Northern Region of Senegal
No full textIntroduction: Chronic kidney disease (CKD) is closely linked to high blood pressure (HBP), which is its leading cause in developing countries. Hypertension affects 1.2 billion people worldwide. However, a significant portion of individuals with HBP are undiagnosed, and their kidney function is even less known. The objective of this study was to determine the prevalence and associated factors of CKD among three sub-groups of blood pressure status (normotensive, diagnosed hypertension, and undiagnosed hypertension) individuals. Patients and Methods: We conducted a cross-sectional study in the general population of three northern regions in Senegal using a two-level cluster sampling method. The sample was constituted with a precision of 5% and a power of 80%, with an additional 10% attrition margin. Individuals aged 18–80 years were included in the study after consent. Pregnant women, hospitalized persons within the past 3 months, patients with general or urinary symptoms within the past 7 days and individuals undergoing renal replacement therapy were excluded. Investigators collected clinical and biological data at participants’ homes using a modified version of the WHO’s STEPwise questionnaire. Samples were collected for biochemical analysis (serum creatinine, lipid profile, and blood sugar). Estimated glomerular filtration rate was calculated using the CKD-EPI 2021 formula. Results: A total of 2,441 participants were included in the study with a mean age of 45.4 ± 16.0 years and a sex ratio M/F of 0.4. The overall prevalence of HBP and CKD were, respectively, 52.0% and 17.8%. Three out of every five hypertensive patients were undiagnosed. CKD was more frequent among known hypertensive patients (30.5%) compared to individuals with undiagnosed hypertension (19.1%) and normotensive individuals (10.9%). Multivariate analysis showed that CKD was associated with older age and female sex. Conclusion: Undiagnosed hypertension is common among populations in northern Senegal. A high prevalence of CKD was found among both diagnosed and undiagnosed individuals with hypertension. Extending strategies for early detection and management in the general population could help prevent or reduce morbidity and mortality associated with CKD
Evaluation of Access to Care for Patients with Chronic Kidney Disease Not on Dialysis in Saint-Louis Region (SENEGAL)
No full textInternational audienc
Prevalence and Psychosocial Impact of Coronavirus Disease 2019 in Chronic Hemodialysis Patients in Dakar, Saint-Louis, and Ziguinchor: A Prospective Multicentric Study between February 2020 and June 2020
No full textChronic hemodialysis (HD) patients are particularly vulnerable to coronavirus disease 2019 (COVID-19). We assessed the prevalence and psychosocial impact of COVID-19 in these patients in Senegal. This multicenter prospective, descriptive, and analytical study included 345 patients who had been on chronic HD for at least 1 month (average age = 49.67 ± 14.58 years; sex ratio: 1.14). Eighty-one patients (23.48%) believed that COVID-19 negatively impacted their dialysis treatment. In total, 257 patients (74.49%) perceived themselves to be at risk, and 128 patients (37.1%) were worried about attending the dialysis center. Only 109 patients (31.59%) were tested by polymerase chain reaction; 13 (11.92%) were positive. In total, 322 patients (93.6%) were informed through television or radio, 338 (97.97%) were aware of the barrier measures, and 83 (24.06%) had difficulty applying the barrier measures, mainly on transport. Masks were the best-known measure, as reported by 331 patients (95.94%). In a bivariate analysis, knowledge of the barrier measures was associated with education level (P <0.001). Perceptions of the risk of COVID-19 were associated with knowledge of the barrier measures (P = 0.05), whereas transport difficulties were associated with socio-professional activity (P = 0.048) and education level (P = 0.007). Difficulties with exploration were associated with socio-professional activity (P <0.001) and educational level (P = 0.003). We found that COVID-19 was a problem among chronic HD patients in Senegal, most of whom had a good knowledge of the barrier measures. The pandemic created anxiety and difficulties in transport, drug supply, and access to specialized care among these patients
Some of the works of Serigne Mouhammadou Masokhna Lo
No full textDate created: 1980s.The entire manuscript is available for download below as a single PDF file. Each page is also available as a separate, larger, JPG file. If higher-resolution JP2 files are needed (WARNING: files average 11-14MB in size), please contact [email protected].
Fieldwork Team: Dr. Fallou Ngom (PI), Cheikh Tidiane Fall (Co-applicant), Ablaye Diakite (Researcher), Birane Gassama (Researcher)
Technical Team: Roger Brisson (Head of Metadata Services, BU Libraries), Vika Zafrin (Institutional Repository Librarian, BU Libraries), Jack Ammerman (Associate University Librarian for Digital Initiatives and Open Access, BU Libraries), and Dr. Peter Quella.
This collection of Wolofal (Wolof Ajami) materials is copied as part of the EAP 334 Project (Digital Preservation of Wolof Ajami manuscripts of Senegal) led by Dr. Fallou Ngom in collaboration with WARA/WARC and Boston University Library. The project is funded by the British Library/Arcadia Endangered Archives.
Access Condition and Copyright: The materials are subject to copyright. Access is for research and educational purposes only. Materials are not to be reproduced without written permission.
Citation: Materials in this web edition may be cited as: Ngom, Fallou. 2011. African Ajami Library: EAP 334. Digital Preservation of Wolof Ajami Manuscripts of Senegal. Boston: Boston University Library: http://dcommon.bu.edu
For Inquires: Please, contact Professor Fallou Ngom ([email protected])These manuscripts are the originals handwritten by Serigne Mouhammadou Masokhna Lo. Based on the interview with the author, they were written in the 1980s. Red, green, and black ink are used in the manuscripts. The red and green ink are used to highlight key words and phrases. There are frequent insertions of Arabic phrases, which include quranic quotations and opening and closing formulae. The manuscripts contain several poems written by Serigne Mouhammadou Masokhna Lo, including a biographical eulogy of Serigne Mor Mbaye Cisse, a renowned Murid scholar and educator who lived and taught in Diourbel; and criticisms of social problems such as lack of discipline and good behavior, disorderly conduct, adultery, the negative consequences of alcoholism among men, women, young and old, and among leaders and their followers. The materials also include historical accounts of the five year long construction of the mosque of Diourbel (Jumaay Ndiaareem) using chronograms; the discussion between Serigne Modou Moustapha (who led the effort) and the French engineer responsible for the construction on the equipment needed; the construction of the railway between Diourbel and Touba; the personal qualities of Serigne Bassirou Mbacke; a tribute to Cheikh Ahmadou Bamba and to Serigne Mbacke Madina; the motivation of 28 kaamil (copies of the Qur'an) written by Serigne Fallou Mbacke for his father and spiritual guide Cheikh Ahmadou Bamba; and a tribute to Serigne Bousso, among others. The materials also contain a poem on coffee and its benefits.
Digitized on 17 July 2011.
According to the author, the documents were written in the 1980s.
Some images are difficult to read due to the poor condition of both the originals, which have ink stains, and the writing (especially those entirely written with black inks). The ink has faded away in some pages.This collection of Wolofal (Wolof Ajami) materials is copied as part of the EAP 334 Project (Digital Preservation of Wolof Ajami manuscripts of Senegal) led by Dr. Fallou Ngom in collaboration with WARA/WARC and Boston University Library. The project is funded by the British Library/Arcadia Endangered Archives
L’hyperthyroïdie de l’enfant au centre hospitalier universitaire de Dakar (Sénégal)
No full textIntroduction: L'hyperthyroïdie de l'enfant semble rare et constitue un problème de par son retentissement psychosomatique. L’objectif était defaire le point sur ses aspects épidémiologiques et diagnostiques chez l’enfant à Dakar.Méthodes: Il s'agissait d'une étude multicentrique, descriptive sur 15 ans. Etaient analysés les aspects épidémiologiques, cliniques et étiologiques. Résultats: 239 patients sélectionnés avec une prévalence de 2.4%, un sex ratio (H/F) de 0.36, un âge moyen de 10.8 ans. À l'inclusion, il s'agissait d'un ainé de famille (26.3%), d'une croissance avancée (36.9%), retardée (12.5%), d'une corpulence insuffisante (40.1%). L'étiologie était la maladie de Basedow dans 90.3% avec un facteur psychoaffectif dans 22.1%. Sur le plan clinique, prédominaient la tachycardie (92.4%), le goitre (91.1%), l'exophtalmie (81.8%), l'amaigrissement (69.8%) avec cependant une énurésie (30.2%) et des manifestations psychiques (3.1%). Les manifestations cardiovasculaires et cutanées étaient positivement associées avec l'âge (p < 0.05). Le goitre était associé au sexe féminin (p = 0.005), aux signes cardiovasculaires (p = 0.02), neuropsychiques (p = 0.03), cutanées (p = 0.03) et à la diarrhée (p = 0.03). La T4 libre était corrélée à l'âge (p = 0.007), la diarrhée (p = 0.021), l'anxiété (p = 0.024), la fréquence cardiaque (p = 0.00) et la maladie de Basedow (p = 0.04). Plus le goitre était volumineux, plus était augmentée la T4 libre (p = 0.007). Conclusion: L'hyperthyroïdie de l'enfant se différencie de celle de l'adulte par les facteurs d'induction, les perturbations sur la croissance et l'énurésie. L’âge et le sexe semble favoriser le tableau clinique de thyrotoxicose et les signes associés.Mots clés: Hyperthyroïdie, enfant, Sénéga
Evaluation des complications cardiovasculaires au centre d’hémodialyse de l’hôpital régional de Ziguinchor au sud du Sénégal.
No full textIntroduction : Les complications cardiovasculaires sont très létales chez les patients hémodialysés chroniques. Elles constituent la première cause de mortalité dans cette population qui est 3 à 20 fois plus élevée par rapport á la population générale de même âge.L’objectif de ce travail était de déterminer la fréquence des complications cardiovasculaires chez les patients hémodialysés chroniques.Patients et méthodes : Il s’agissait d’une étude prospective descriptive et analytique de 2 mois au centre d’hémodialyse de l’hôpital régional de Ziguinchor.Le recueil des données était effectué grâce á un questionnaire renseignant sur les paramètres épidémiologiques, cliniques, paracliniques. Tous les patients avaient bénéficié d’un électrocardiogramme et d’une échographie cardiaque trans-thoracique faites en post dialyse.Résultats : L’âge moyen des patients était de 41,14 ans et 57,14% des patients étaient hypertendus. La dyspnée d’effort était la principale manifestation clinique soit 47,61% et 28,57% des patients avaient une hypertrophie ventriculaire gauche électrique. A l’échocoeur, l’hypertrophie ventriculaire gauche concentrique était le plus notée dans 47,61%.Conclusion : les patients hémodialysés chroniques sont exposés á des complications cardiovasculaires fréquentes et létales. La prise en charge correcte nécessite une surveillance avec des examens paracliniques périodique pour prévenir les complications
Usefulness of foot-to-foot bioimpedance analysis for assessing volume status in chronic hemodialysis patients at the Aristide Le Dantec University Hospital (Senegal)
No full textIntroduction: Determination of dry weight is one of the daily goals to achieve in hemodialysis. The aim of this study was to validate the use of bioelectrical impedance analysis (BIA) in estimation of dry weight in a population of Senegalese chronic hemodialysis patients.
Patients and methods: A 9-week cross-sectional study was carried out at the hemodialysis unit of Aristide Le Dantec University Hospital. Adult patients with no previous hospital history were included. The total body water (TBW) was measured with a single frequency bioelectric impedance foot-to-foot analyzer, before and after six successive hemodialysis sessions. These results were compared with those from clinical measurements with the Watson equation using a Student’s t-test and Bland-Altman analysis.
Results: 264 measurements were made in 22 patients (46.6 years, 54.5% men, 92.3 months on dialysis, 62.7 kg mean dry weight). A significant reduction in weight (ΔWeight = 2.0 ± 1.1 kg; p < 0.0001) and in TBW measured by the BIA (ΔTBWBIA = 3.3 ± 1.0 liters; p < 0.0001)) or calculated by Watson’s equation (ΔTBWWatson = 0.5 ± 0.2 liter; p = 0.0001) was observed. There was a strong linear correlation and agreement between the 2 TBW measurements in pre-dialysis. In post-dialysis the concordance diagram indicated a bias = –2.2 and wide agreement limits.
Conclusion: The BIA allows reproducible and reliable measurements and a fair estimate of the TBW in pre-dialysis
