1,721,689 research outputs found
Molecular mechanism of cannabinoids in cancer progression [*Pagano C. *Navarra G. co-first authors]
No full textCannabinoids are a family of heterogeneous compounds that mostly interact with receptors eliciting several physiological effects both in the central and peripheral nervous systems and in peripheral organs. They exert anticancer action by modulating signaling pathways involved in cancer progression; furthermore, the effects induced by their use depend on both the type of tumor and their action on the components of the endocannabinoid system. This review will explore the mechanism of action of the cannabinoids in signaling pathways involved in cancer prolifera-tion, neovascularisation, migration, invasion, metastasis, and tumor angiogenesis
Contingency: a path between Avicenna’s al-Ilāhiyyāt and Duns Scotus’s Quaestiones Super Libros Metaphysicorum
No full textThis paper aims to contribute to the history of the concept of contingency as it
has been developed by John Duns Scotus in his Quaestiones Super Libros Metaphysicorum
in light of his reception of Avicenna’s metaphysics (al-Ila
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hı
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yya
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t) from the Kita
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b al-Šifa
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’.
As is known, an intermediary role was played by Henry of Ghent’s ontology. The focus is
here the peculiarity of Scotus’s new way of thinking about the modalities of being in rela-
tion to metaphysics, in light of the speculations of Avicenna and Henry of Ghent. Lastly, I
consider the juxtaposition of Avicenna’s conception of essences and Duns Scotus’s model
of potencies with Frege’s doctrine of the ‘Third Realm’ of truths
Astrology as the «Queen of Sciences» in Michael Scot’s Liber introductorius
No full textThroughout the history of Western thought, astrology has been viewed as either
a dangerous or false science, or as a true and superior science or art, that can pro-
vide practitioners with access to divine truth. However, a middle ground appears un-
attainable. The article presents two opposing perspectives on astrology: Theodor W.
Adorno’s contemporary view, which considers astrology as an instrument of power
in consumer society, and Michael Scot’s scientific foundation of astrology developed
during the Middle Ages in light of Arabic-Latin translations. The aim of the article
is to show how Scotus’ epistemology establishes «the science of the stars» as the
supreme science and places the human being and the study of the soul at the centre
of the cosmos in the 4th distinction of the Liber introductorius, known as De anima
La cosmologia degli arabi: Alessandro di Afrodisia e il trattato Sul governo delle sfere celesti,
No full textFrom Toledo to the Court of Frederick II. The ‘Science of the Stars’ and the Human Soul in the 4th distinctio (De anima) of Michael Scot’s Liber introductorius
No full textThis contribution aims to introduce Michael’s doctrine of the soul, developed in
the 4th distinctio of the Liber quatuor distinctionum, and to show how the soul is the fulcrum
of Michael’s scientific reflection on astrology. Furthermore, some close similarities between
Michael’s Liber introductorius and one of the best-known encyclopaedic works of the An-
dalusian world, the Epistles of the Ikhwān al-Ṣafāʾ, shed light on the richness of the Toledan
milieu of the time and Michael Scot’s formative period in Toledo
Book Review: Alessandra Beccarisi – Alessandro Palazzo (eds.), Per studium et doctrinam. Fonti e testi di filosofia medievale dal XII al XIV secolo. Studi in onore di Loris Sturlese, Flumen Sapientiae 6, Aracne, Roma 2018
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La mente di Dante. Visioni, percezioni, rappresentazioni”, 30 settembre - 3 ottobre 2021, Lecce (Italia): Università del Salento
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