1,721,027 research outputs found

    Ileal Conduit as the Standard for Urinary Diversion After Radical Cystectomy for Bladder Cancer

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    For >30 yr, the ileal conduit (IC) has been considered the " standard" urinary diversion for bladder cancer patients submitted to radical cystectomy. It is universally recognised as being the most clinically adequate, cost-effective, and reliable solution in the long term. During the last two decades, this surgical procedure has been challenged by the dissemination and the excellent clinical outcome of bladder substitutions, which gave the surgeon options in supporting the patient's final choice. Despite this, from a survey of recent literature, IC remains a widely used urinary diversion in most urologic centres. In particular, it is most frequent in female patients and in patients >70 yr with high preoperative comorbidities and unfavourable clinical tumour stage.Enhanced recovery protocols with standardised perioperative plans of care or " fast-track" approaches as well as advances in postoperative patient surveillance have consistently decreased the overall morbidity related to the IC procedure. Although technically simpler to perform when compared with continent reservoirs, IC has not been associated with lower complications. This can be explained partly by the more unfavourable clinical characteristics of patients who undergo the procedure and partly by technical surgical errors. Postoperative complications strictly related to IC contribute to reduce the postoperative quality of life. These complications include uretero-ileal anastomotic strictures and stomal, peristomal, and abdominal wall-related complications. Most prospective studies, however, found no difference in overall quality of life when comparing different types of transposed intestinal segment surgery. The ileal conduit can still be considered an appropriate surgical solution after radical cystectomy in most patients because of the relative simplicity of the surgical technique, the acceptable complication rate, and the satisfactory postoperative quality of life. © 2010 European Association of Urology

    Laparoscopic adrenalectomy and adrenal-preserving surgery

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    Purpose of review: The aim of this paper is to define the current role of laparoscopy in the management of surgical adrenal diseases evaluating the surgical aspects, the indications and contraindications of laparoscopic adrenalectomy, focusing also on the most innovative tendencies in the laparoscopic adrenal-preserving surgery. Recant findings: Recent publications have described some interesting new indications that need to be confirmed by long-term follow up. The present review mainly focuses on defining the state of the art of current adrenal laparoscopic surgery. Summary: Laparoscopic adrenalectomy is becoming the 'platinum standard' for the treatment of the adrenal surgical diseases and it should be considered the treatment of choice for benign adrenal diseases. In cases of malignancy and conservative surgery, adrenalectomy appears to be very promising, although a longer follow up and further studies are still needed to accurately assess the role played by these procedures. Finally, who should do laparoscopic adrenalectomy? Every patient who requires the ablation of the adrenal should receive laparoscopic opportunity. And the surgeons? Only those with advanced laparoscopic skills and a good knowledge of adrenal anatomy and pathophysiology will obtain the same excellent results currently reported in the literature. © 2005 Lipptncott Williams & Wilkins

    Primary and Pure Neuroendocrine Tumor of the Prostate

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    Primary neuroendocrine tumors of the prostate are very rare and their biologic behaviour is not yet well known. Clinical and histopathologic features of two cases, one with lymph-node involvement and one organ-confined are described. Young age, clinical presentation and good outcome after radical retropubic prostatectomy were comparable in both patients. © 2003 Elsevier B.V. All rights reserved

    Urology in the time of corona

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    The world is currently in the grip of the COVID-19 pandemic. Rapid changes in medical priorities are being enforced across all health-care systems. Urologists have had to reduce or halt their clinical activity and assist on COVID-19 wards. The repercussions on urological patient outcomes for delayed treatments and diagnosis remain to be defined

    Update of the minimally invasive therapies for benign prostatic hyperplasia

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    Purpose of review: The elevated impact benign prostatic hyperplasia has on patient quality of life has determined continuous research into the development of minimally invasive therapies aimed at restoring or preserving a good quality of life. The purpose of this review is to highlight recent developments in the field of minimally invasive treatment of benign prostatic hyperplasia, and to determine their possible impact on everyday clinical practice. Recent findings: Recent publications have described some interesting new therapies and provided data concerning long-term follow up and cost-effectiveness that have been lacking up until now. The review mainly focuses on transurethral microwave thermotherapy, interstitial laser coagulation, transurethral laser ablation, laser prostatectomies (resection and enucleation), transurethral ethanol injection therapy, transurethral electrovaporization, and high-power (80-W) potassium titanyl phosphate laser vaporization. Summary: Recent developments, new approaches and long-term reports of previously described minimally invasive therapies for the treatment of benign prostatic hyperplasia are presented. Cost-effectiveness studies were also carried out to complete the comparison with standard everyday procedures. Currently, transurethral microwave thermotherapy seems to offer the soundest basis for management of the condition, providing the longest term follow up and the largest numbers of studies completed to date. Among surgical alternatives, holmium laser enucleation has gained ground as an encouraging new approach, being similar to standard transurethral resection of the prostate, but reducing perioperative morbidity with the same long-term results. More randomized comparisons correctly conducted need to be undertaken before an accurate general picture is available for the urologist. © 2005 Lippincott Williams & Wilkins
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